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p38 Mitogen-activated protein kinases is required for counteraction of 2-methoxyestradiol to estradiol-stimulated cell proliferation and induction of apoptosis in ovarian carcinoma cells via phosphorylation Bcl-2

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  1. Article

    Open Access

    Alterations of GPI transamidase subunits in head and neck squamous carcinoma

    GPI anchor attachment is catalyzed by the GPI transamidase (GPIT) complex. GAA1, PIG-T and PIG-U are the three of five GPIT subunits. Previous studies demonstrated amplification and overexpression of GPIT subunit...

    Wei-Wen Jiang, Marianna Zahurak, Zeng-Tong Zhou, Hannah Lui Park in Molecular Cancer (2007)

  2. Article

    Open Access

    Maintenance of Sorafenib following combined therapy of three-dimensional conformal radiation therapy/intensity-modulated radiation therapy and transcatheter arterial chemoembolization in patients with locally advanced hepatocellular carcinoma: a phase I/II study

    Three-dimensional conformal radiation therapy (3DCRT)/intensity-modulated radiation therapy (IMRT) combined with or without transcatheter arterial chemoembolization (TACE) for locally advanced hepatocellular c...

    Jian-Dong Zhao, ** Liu, Zhi-Gang Ren, Ke Gu, Zhen-Hua Zhou in Radiation Oncology (2010)

  3. Article

    Open Access

    Impact of residual and intrafractional errors on strategy of correction for image-guided accelerated partial breast irradiation

    The cone beam CT (CBCT) guided radiation can reduce the systematic and random setup errors as compared to the skin-mark setup. However, the residual and intrafractional (RAIF) errors are still unknown. The pur...

    Gang Cai, Wei-Gang Hu, Jia-Yi Chen, **ao-Li Yu, Zi-Qiang Pan in Radiation Oncology (2010)

  4. Article

    Open Access

    Neck dissection and post-operative chemotherapy with dimethyl triazeno imidazole carboxamide and cisplatin protocol are useful for oral mucosal melanoma

    Oral mucosal melanoma (OMM) is a clinically rare disease with poor prognosis. Various treatment methods have been investigated with the aim of improving the prognosis. This study aimed to analyze the data of a...

    ** Yang, Guo-xin Ren, Chen-** Zhang, Guo-yu Zhou, Yong-jie Hu, Wen-jun Yang in BMC Cancer (2010)

  5. Article

    Open Access

    Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert's syndrome

    Acute leukemia with coexisting Gilbert's syndrome treated by allogeneic hematopoietic stem cell transplantation (allo-HSCT) is rarely reported. Here we described a case whose transaminase levels were almost no...

    Guo-Pan Yu, Qian-Li Jiang, Zhi-** Fan, Jie Zhao in Journal of Hematology & Oncology (2011)

  6. Article

    Open Access

    Use of combined maximum and minimum intensity projections to determine internal target volume in 4-dimensional CT scans for hepatic malignancies

    To evaluate the accuracy of the combined maximum and minimum intensity projection-based internal target volume (ITV) delineation in 4-dimensional (4D) CT scans for liver malignancies.

    ** Liu, Jia-Zhou Wang, Jian-Dong Zhao, Zhi-Yong Xu, Guo-Liang Jiang in Radiation Oncology (2012)

  7. Article

    Open Access

    PRAF3 induces apoptosis and inhibits migration and invasion in human esophageal squamous cell carcinoma

    Prenylated Rab acceptor 1 domain family member 3 (PRAF3) is involved in the regulation of many cellular processes including apoptosis, migration and invasion. This study was conducted to investigate the effect...

    Guo-Zhen Shi, Yang Yuan, Guo-Jun Jiang, Zhi-Jun Ge, Jian Zhou, De-Jun Gong in BMC Cancer (2012)

  8. Article

    Open Access

    Long-term outcome of irradiation with or without chemotherapy for esophageal squamous cell carcinoma: a final report on a prospective trial

    To investigate the long-term outcome of esophageal squamous cell carcinoma (SCC) treated by irradiation with or without concurrent chemotherapy.

    Mina Liu, Xuehui Shi, **aomao Guo, Weiqiang Yao, Yong Liu in Radiation Oncology (2012)

  9. Article

    Open Access

    Fractionated stereotactic radiotherapy for 136 patients with locally residual nasopharyngeal carcinoma

    To evaluate the efficacy and toxicity of fractionated stereotactic radiotherapy (FSRT) in patients with residual nasopharyngeal carcinoma (NPC).

    Feng Liu, Guo-zhen Xu, Li Gao, Ying-jie Xu, Ye Zhang in Radiation Oncology (2013)

  10. Article

    Open Access

    The clinical value of the quantitative detection of four cancer-testis antigen genes in multiple myeloma

    Cancer-testis (CT) antigen genes might promote the progression of multiple myeloma (MM). CT antigens may act as diagnostic and prognostic markers in MM, but their expression levels and clinical implications in...

    Yao Zhang, Li Bao, ** Lu, Kai-Yan Liu, **-Lan Li, Ya-Zhen Qin in Molecular Cancer (2014)

  11. Article

    Open Access

    Exogenous norepinephrine attenuates the efficacy of sunitinib in a mouse cancer model

    Sunitinib alone exhibits satisfactory efficacy in several mouse homografts and xenografts but unsatisfactory efficacy in many kinds of solid tumors in clinic. Different from animals, receiving a diagnosis of c...

    Guo-Hua Deng, Jie Liu, Jie Zhang, Ying Wang in Journal of Experimental & Clinical Cancer … (2014)

  12. Article

    Open Access

    Silencing of ETS1 reverses adriamycin resistance in MCF-7/ADR cells via downregulation of MDR1

    Clinical resistance to chemotherapeutic agents is one of the major hindrances in the treatment of human cancers. Erythroblastosis virus E26 oncogene homolog 1 (ETS1) is involved in the drug resistance of vario...

    **rong Wei, Yong Zhou, Guo-Qin Jiang, Dong **ao in Cancer Cell International (2014)

  13. Article

    Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

    Nat. Genet. 42, 759–763 (2010); published online 22 August 2010; corrected after print 27 August 2014 In contrast to the version of this article initially published, the authors now find no evidence to support...

    Li-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, **n Song, Yan ** in Nature Genetics (2014)

  14. Article

    Open Access

    Evaluation of the value of ENI in radiotherapy for cervical and upper thoracic esophageal cancer: a retrospective analysis

    A retrospective study to compare the failure patterns and effects of elective nodal irradiation (ENI) or involved field irradiation (IFI) for cervical and upper thoracic esophageal squamous cell carcinoma (SCC...

    Mina Liu, Kuaile Zhao, Yun Chen, Guo-Liang Jiang in Radiation Oncology (2014)

  15. Article

    Open Access

    Downregulation of miR-610 promotes proliferation and tumorigenicity and activates Wnt/β-catenin signaling in human hepatocellular carcinoma

    Wnt/β-catenin signaling pathway plays important roles in human cancer progression. Better understanding the mechanism underlying regulation of Wnt/β-catenin signaling pathway might provide novel therapeutic ta...

    **an-Cheng Zeng, Fo-Qiu Liu, Rong Yan, Hui-Min Yi, Tong Zhang in Molecular Cancer (2014)

  16. Article

    Open Access

    Intensity modulated radiotherapy for locally advanced and metastatic pancreatic cancer: a mono-institutional retrospective analysis

    To evaluate the role of intensity modulated radiotherapy (IMRT) for locally advanced pancreatic cancer (LAPC) and metastatic pancreatic cancer (MPC), and the prognostic factors in the setting of multidisciplin...

    Zheng Wang, Zhi-Gang Ren, Ning-Yi Ma, Jian-Dong Zhao, Zhen Zhang in Radiation Oncology (2015)

  17. Article

    Open Access

    Elevated C1orf63 expression is correlated with CDK10 and predicts better outcome for advanced breast cancers: a retrospective study

    Chromosome 1 open reading frame 63 (C1orf63) is located on the distal short arm of chromosome 1, whose allelic loss has been observed in several human cancers. C1orf63 has been reported to be up-regulated in I...

    Chao-Qun Hong, Fan Zhang, Yan-Jie You, Wei-Li Qiu, Armando E. Giuliano in BMC Cancer (2015)

  18. Article

    Open Access

    Metformin can block precancerous progression to invasive tumors of bladder through inhibiting STAT3-mediated signaling pathways

    Metformin is the first line of oral antidiabetic drug in the biguanide class for treatment of type 2 diabetes. Increasing evidence has suggested that it is a potential anti-tumor drug. However, the mechanisms ...

    Qi Pan, Guo-Liang Yang, Jiang-Hua Yang in Journal of Experimental & Clinical Cancer … (2015)

  19. Article

    Retraction Note to: Correlation of IL-1F genetic polymorphisms with the risk of colorectal cancer among Chinese populations

    Ming Ma, Guo-Jiang **, Ke Yun, Run-Qing Mu, Min Zhao, **ao-Ou Yu in Tumor Biology (2015)

  20. Article

    MiR-125b promotes cell migration and invasion by targeting PPP1CA-Rb signal pathways in gastric cancer, resulting in a poor prognosis

    MiR-125b functions as an oncogene in many cancers; however, its clinical significance and molecular mechanism in gastric cancers have never been sufficiently investigated. Here, we elucidated the functions and...

    Jian-Guo Wu, **-Jie Wang, **n Jiang, Jian-** Lan, Xu-Jun He in Gastric Cancer (2015)

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