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Open AccessThrombocytopenia in the experimental leptospirosis of guinea pig is not related to disseminated intravascular coagulation
Thrombocytopenia is commonly observed in severe leptospirosis. However, previous studies on coagulation alterations during leptospirosis resulted in inconsistent conclusions. Some findings showed that the prom...
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Article
Open AccessPrevalence of syphilis infection in different tiers of female sex workers in China: implications for surveillance and interventions
Syphilis has made a dramatic resurgence in China during the past two decades and become the third most prevalent notifiable infectious disease in China. Female sex workers (FSWs) have become one of key populat...
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Erratum to: Multidisciplinary intensive care in extensive necrotizing fasciitis
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Open AccessRapid assessment of knowledge, attitudes, practices, and risk perception related to the prevention and control of Ebola virus disease in three communities of Sierra Leone
The recent outbreak of the Ebola virus disease (EVD) in Sierra Leone has been characterized by the World Health Organization as one of the most challenging EVD outbreaks to date. The first confirmed case in Si...
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Open AccessA practical community-based response strategy to interrupt Ebola transmission in sierra Leone, 2014–2015
The Ebola virus disease spread rapidly in West Africa in 2014, leading to the loss of thousands of lives. Community engagement was one of the key strategies to interrupt Ebola transmission, and practical commu...
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Open AccessMulti-locus variable-number tandem repeat analysis of Chinese Brucella strains isolated from 1953 to 2013
Brucellosis was a common human and livestock disease caused by Brucella strains, the category B priority pathogens by the US Center for Disease Control (CDC). Identified as a priority disease in human and livesto...
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Article
Open AccessIL-6 and INF-γ levels in patients with brucellosis in severe epidemic region, **njiang, China
The incidence of brucellosis, which is caused by the Brucella species of bacteria, is rapidly rising worldwide; however, few studies have investigated the immune response to this pathogen and clinical biochemical...
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Article
Open AccessClinical characteristics of different subtypes and risk factors for the severity of illness in patients with COVID-19 in Zhejiang, China
The outbreak of coronavirus disease 2019 (COVID-19) is now becoming an enormous threat to public health. The clinical spectrum of COVID-19 is extensive, of which critical cases are with rapid disease progressi...
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Open AccessAnalysis and predication of tuberculosis registration rates in Henan Province, China: an exponential smoothing model study
The World Health Organization End TB Strategy meant that compared with 2015 baseline, the reduction in pulmonary tuberculosis (PTB) incidence should be 20 and 50% in 2020 and 2025, respectively. The case numbe...
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Open AccessHigh prevalence of Clonorchis sinensis infection in Guangxi, Southern China
Soil-transmitted helminths (STHs), such as hookworm, roundworm and whipworm, and food-borne trematodiases, including Clonorchis sinensis, remain a public health problem worldwide, especially in tropical and subtr...
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Open AccessMolecular characteristics of Brucella melitensis isolates from humans in Qinghai Province, China
The prevalence of human brucellosis in Qinghai Province of China has been increasing rapidly, with confirmed cases distributed across 31 counties. However, the epidemiology of brucellosis transmission has not ...
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Open AccessFluorescence polarization assay improves the rapid detection of human brucellosis in China
Brucellosis is an infectious-allergic zoonotic disease caused by bacteria of the genus Brucella. Early diagnosis is the key to preventing, treating, and controlling brucellosis. Fluorescence polarization immunoas...
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Open AccessDynamic changes in liver function parameters in patients with coronavirus disease 2019: a multicentre, retrospective study
Liver injuries have been reported in patients with coronavirus disease 2019 (COVID-19). This study aimed to investigate the clinical role played by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
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Open AccessImpact of immune checkpoint molecules on FoxP3+ Treg cells and related cytokines in patients with acute and chronic brucellosis
The immunoregulatory functions of regulatory T cells (Tregs) in the development and progression of some chronic infectious diseases are mediated by immune checkpoint molecules and immunosuppressive cytokines. ...
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Open AccessInhibition of STAT3 alleviates LPS-induced apoptosis and inflammation in renal tubular epithelial cells by transcriptionally down-regulating TASL
Systemic lupus erythematosus (SLE) is a common autoimmune disease that impacts various organs. Lupus nephritis (LN) significantly contributes to death in children with SLE. Toll-like receptor (TLR) adaptor int...