30 Result(s)

Article

Transplantation of marrow stromal cells to rescue retinal cells in SI-induced retinal degeneration in rats

Yuan Guan, Lu Cui, Yuanyuan Gong, Caihong **a, Naihe **g, Yalan Wu… in Cell Research (2008)

Article

Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601

The virulence-attenuated Leptospira interrogans serovar Lai strain IPAV was derived by prolonged laboratory passage from a highly virulent ancestral strain isolated in China. We studied the genetic variations of ...

Yi Zhong, **ao Chang, **ng-Jun Cao, Yan Zhang, Huajun Zheng, Yongzhang Zhu… in Cell Research (2011)

Article

A functional variant in the cystathionine β-synthase gene promoter significantly reduces congenital heart disease susceptibility in a Han Chinese population

Homocysteine is an independent risk factor for various cardiovascular diseases. There are two ways to remove homocysteine from embryonic cardiac cells: remethylation to form methionine or transsulfuration to f...

Jian-Yuan Zhao, Xue-Yan Yang, Kai-Hu Shi, Shu-Na Sun, Jia Hou, Zhi-Zhou Ye… in Cell Research (2013)

Article

IRF4 is a novel mediator for neuronal survival in ischaemic stroke

Neuroprotection following ischaemic stroke is driven by the interplay between regulatory transcription factors and endogenous protective factors. IRF4, a member of the interferon regulatory factor (IRF) family...

S Guo, Z-Z Li, D-S Jiang, Y Y Lu, Y Liu, L Gao, S-M Zhang… in Cell Death & Differentiation (2014)

Article

A molecular roadmap for induced multi-lineage trans-differentiation of fibroblasts by chemical combinations

Recent advances have demonstrated the power of small molecules in promoting cellular reprogramming. Yet, the full potential of such chemicals in cell fate manipulation and the underlying mechanisms require fur...

** Han, Hao Yu, Daosheng Huang, Yang Xu, Assieh Saadatpour, **a Li… in Cell Research (2017)

Article

Erratum: A molecular roadmap for induced multi-lineage trans-differentiation of fibroblasts by chemical combinations

Correction to: Cell Research (2017) 27:386–401. doi:10.1038/cr.2017.17; published online on 27 January 2017 The authors apologized for the mistake of mis-labeling the affiliation for Dr Stuart H Orkin, his aff...

** Han, Hao Yu, Daosheng Huang, Yang Xu, Assieh Saadatpour, **a Li… in Cell Research (2017)

Article

Erratum: A molecular roadmap for induced multi-lineage trans-differentiation of fibroblasts by chemical combinations

Correction to: Cell Research (2017) 27:386–401. doi:10.1038/cr.2017.17; published online on 27 January 2017 During web production, there is an error in the web site for the labeling of Dr Bin Zhou, his affilia...

** Han, Hao Yu, Daosheng Huang, Yang Xu, Assieh Saadatpour, **a Li… in Cell Research (2017)

Article

H19/let-7/LIN28 reciprocal negative regulatory circuit promotes breast cancer stem cell maintenance

Long noncoding RNA-H19 (H19), an imprinted oncofetal gene, has a central role in carcinogenesis. Hitherto, the mechanism by which H19 regulates cancer stem cells, remains elusive. Here we show that breast cancer ...

Fei Peng, Ting-Ting Li, Kai-Li Wang, Guo-Qing **ao, Ju-Hong Wang… in Cell Death & Disease (2018)

Article

Elimination of stem-like cancer cell side-population by auranofin through modulation of ROS and glycolysis

Cancer side-population (SP) represents a sub-population of stem-like cancer cells that have an important role in drug resistance due to their high expression of the ATP-binding cassette transporter ABCG2 invol...

Guo-**n Hou, Pan-Pan Liu, Shengyi Zhang, Mengqi Yang, Jianwei Liao… in Cell Death & Disease (2018)

Article

SLIT2/ROBO1 axis contributes to the Warburg effect in osteosarcoma through activation of SRC/ERK/c-MYC/PFKFB2 pathway

Cellular metabolic reprogramming is the main characteristic of cancer cells and identification of targets using this metabolic pattern is extremely important to treat cancers, such as osteosarcoma (OS). In thi...

Shu-Jie Zhao, Yi-Fei Shen, Qing Li, Yun-Jie He, Yun-Kun Zhang… in Cell Death & Disease (2018)

Article

Regulation of the master regulator FOXM1 in cancer

FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the processes of cell pr...

Guo-Bin Liao, **n-Zhe Li, Shuo Zeng, Cheng Liu… in Cell Communication and Signaling (2018)

Article

Diverse regulatory manners of human telomerase reverse transcriptase

Human telomerase reverse transcriptase (hTERT) is the core subunit of human telomerase and plays important roles in human cancers. Aberrant expression of hTERT is closely associated with tumorigenesis, cancer ...

Meng-Meng Jie, **ng Chang, Shuo Zeng, Cheng Liu… in Cell Communication and Signaling (2019)

Article

The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer

Pancreatic cancer (PC) is a malignant tumor with a poor prognosis and high mortality. However, the biological role of miR-548t-5p in PC has not been reported. In this study, we found that miR-548t-5p expressio...

Wan-Li Ge, Qun Chen, Ling-Dong Meng, Xu-Min Huang, Guo-dong Shi… in Cell Death & Disease (2020)

Article

N⁶-methyladenine is incorporated into mammalian genome by DNA polymerase

**aoling Liu, Weiyi Lai, Yao Li, Shaokun Chen, Baodong Liu, Ning Zhang… in Cell Research (2021)

Article

New genotypes of Helicobacter Pylori VacA d-region identified from global strains

Pathogenesis of Helicobacter Pylori (HP) vacuolating toxin A (vacA) depends on polymorphic diversity within the signal (s), middle (m), intermediate (i), deletion (d) and c-regions. These regions show distinct al...

Djaleel Muhammad Soyfoo, Yussriya Hanaa Doomah, Dong Xu… in BMC Molecular and Cell Biology (2021)

Article

Author Correction: N⁶-methyladenine is incorporated into mammalian genome by DNA polymerase

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

**aoling Liu, Weiyi Lai, Yao Li, Shaokun Chen, Baodong Liu, Ning Zhang… in Cell Research (2021)

Article

TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca²⁺/CaMKII/Nrf2 signaling pathway

Osteoarthritis (OA) is the major course of joint deterioration, in which M1 macrophage-driven synovitis exacerbates the pathological process. However, precise therapies for M1 macrophage to decrease synovitis ...

Zhongyang Lv, **ngquan Xu, Ziying Sun, Yannick **aofan Yang, Hu Guo… in Cell Death & Disease (2021)

Article

Notch3 inhibits cell proliferation and tumorigenesis and predicts better prognosis in breast cancer through transactivating PTEN

Notch receptors (Notch1–4) play critical roles in tumorigenesis and metastasis of malignant tumors, including breast cancer. Although abnormal Notch activation is related to various tumors, the importance of s...

Yong-Qu Zhang, Yuan-Ke Liang, Yang Wu, Min Chen, Wei-Ling Chen… in Cell Death & Disease (2021)

Article

A negative feedback loop involving NF-κB/TIR8 regulates IL-1β-induced epithelial- myofibroblast transdifferentiation in human tubular cells

Renal tubular epithelial-myofibroblast transdifferentiation (EMT) plays a central role in the development of renal interstitial fibrosis (RIF). The profibrotic cytokine interleukin (IL)-1 and the IL-1 receptor...

Keguo Jiang, Yuying Zhang, Fan He… in Journal of Cell Communication and Signaling (2021)

Article

Discovery of new genetic loci for male sexual orientation in Han population

Epidemiological studies have demonstrated that the genetic factors partly influence the development of same-sex sexual behavior, but most genetic studies have focused on people of primarily European ancestry, ...

Shao-Hua Hu, Hai-mei Li, Hao Yu, Yan Liu, Chen-**ng Liu, **an-bo Zuo… in Cell Discovery (2021)