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Open AccessMicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4
MicroRNA-21 (miR-21) is a key regulator of oncogenic processes. It is significantly elevated in the majority of human tumors and functionally linked to cellular proliferation, survival and migration. In this s...
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BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription
BCL3 is a proto-oncogene affected by chromosomal translocations in some patients with chronic lymphocytic leukemia. It is an IκB family protein that is involved in transcriptional regulation of a number of NF-κB ...
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Particulate matter and manganese exposures in Indianapolis, Indiana
The distribution of PM2.5 and manganese (Mn) personal exposures was determined over a 4-month period in Indianapolis, IN, at a time when the gasoline additive, methylcyclopentadienyl manganese tricarbonyl (MMT), ...
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Dem Ehrenmitglied der Deutschen Gesellschaft für Mund-, Kiefer- und Gesichtschirurgie Prof. Dr. med. Dr. med. dent. Walter Hoffmann-Axthelm zum 90. Geburtstag
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196. Hydroxylapatitkeramik als Knochenersatzmaterial —experimentelle und klinische Ergebnisse
During the last 2 years hydroxyapatite ceramic has been implanted into 18 patients. The frontal region of atrophic mandibulas was augmented with interpositional application of porous hydroxyapatite ceramic in ...
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202. Die einzeitige Wiederherstellung der Nase mit paramedianen Stirnlappen bei Defekten
Since 1970 I have used paramedian forehead flaps with a narrow pedicle (supratrochlear artery and vein) for nasal reconstruction in large defects in 75 patients, after the vessels had been marked by Doppler so...
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Haemodynamic changes in patients with severe head injury
Haemodynamic studies were carried out in 12 patients who had sustained severe head injury. Radial artery pressure (AP), pulmonary artery pressure (PAP), central venous pressure (CVP), and pulmonary wedge press...
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The influence of intravenous anaesthetic agents on primarily increased intracranial pressure
In the choice of anaesthetics and techniques the danger of a possible progressive increase of intracranial pressure (ICP) should be considered. Therefore the influence of intravenous anaesthetic agents on mean...
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Immunologische Aspekte syngenesioplastischer Knochentransplantation bei der Behandlung kindlicher Knochentumoren
Bone transplantations are made often in the treatment of benign bone tumours or tumour like affections. Especially at the appropriate infantile illness the use of an autologous transplant may prove impossible.
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Lungenveränderungen Schädel-Hirn-Verletzter und Beatmung mit hohen Sauerstoffkonzentrationen
An 131 Schädel-Hirn-Traumatisierten wurde festgestellt, wie die Schwere des Schädel-Hirn-Traumas den Krankheitsverlauf beeinflußt, wann und in welchem Umfang röntgenologisch und blutgasanalytisch bestimmbare L...
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Über die Ätiologie der Lippen-Kieferspaltformen und Gaumenspalten beim Menschen und im Tierexperiment
Only formhydroxamic acid and its certain derivatives induce in rats cleft-lip and palate (CLP) after treatment during early embryonic developmental phase. Other hydroxamic acids and formamide-derivatives cause...
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Dokumentation von Patienten mit Lippen-, Kiefer- und Gaumenspalten
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Zur Besiedlung der kindlichen Mundhöhle mit anaeroben Mikroorganismen
Es besteht offenbar kein Zusammenhang zwischen dem Ereignis der Dentition und dem Auftreten von Anaerobiern in der kindlichen Mundhöhle, wie durch Untersuchungen an 120 Säuglingen gezeigt werden konnte.