4 Result(s)
within
Article
Fengtian Sun
English
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Article
Open AccessHypoxic preconditioned MSCs-derived small extracellular vesicles for photoreceptor protection in retinal degeneration
Photoreceptor apoptosis is an important pathogenesis of retinal degeneration and a primary cause of vision loss with limited treatment methods. Mesenchymal stem/stromal cells-derived small extracellular vesicl...
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Engineered Extracellular Vesicles as a Targeted Delivery Platform for Precision Therapy
Extracellular vesicles (EVs)-based cell-free strategy has shown therapeutic potential in tissue regeneration. Due to their important roles in intercellular communications and their natural ability to shield ca...
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Article
Open AccessMesenchymal stem cells-derived small extracellular vesicles alleviate diabetic retinopathy by delivering NEDD4
As a leading cause of vision decline and severe blindness in adults, diabetic retinopathy (DR) is characterized by the aggravation of retinal oxidative stress and apoptosis in the early stage. Emerging studies...
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Article
Open AccessExosomes derived from hucMSC attenuate renal fibrosis through CK1δ/β-TRCP-mediated YAP degradation
Exosomes from human umbilical cord mesenchymal stem cells (hucMSC-Ex) have been suggested as novel nanomaterials for regenerative medicine. Here we explored the roles of hucMSC-Ex through regulating Yes-associ...
