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Article
Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts
Historically, our understanding of mechanisms underlying human leukemogenesis are inferred from genetically engineered mouse models. Relatively, few models that use primary human cells recapitulate the full le...
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Article
High-dose therapy supported with immunomagnetic purged autologous bone marrow in high-grade B cell non-Hodgkin’s lymphoma
From August 1987 to March 1995, 25 patients with high-grade B cell non-Hodgkin’s lymphoma (NHL) were treated with high-dose therapy (HDT) followed by bone marrow purged with immunomagnetic beads. At the time o...
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Article
Demonstration of clonality in neutrophils using FISH in a case of chronic neutrophilic leukemia
A patient previously diagnosed with chronic neutrophilic leukemia (CNL) was studied using fluorescent in situ hybridization (FISH) to determine clonality of neutrophils. By cytogenetic studies the patient’s blood...