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  1. No Access

    Article

    Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling

    Among neurobiological mechanisms underlying antidepressant properties of ketamine, structural remodeling of prefrontal and hippocampal neurons has been proposed as critical. The suggested mechanism involves do...

    L Cavalleri, E Merlo Pich, M J Millan, C Chiamulera, T Kunath… in Molecular Psychiatry (2018)

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    Article

    Neuroimaging as endpoints in clinical trials: Are we there yet? Perspective from the first Provence workshop

    M Valenzuela, D Bartrés-Faz, F Beg, A Fornito, E Merlo-Pich… in Molecular Psychiatry (2011)

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    Article

    Time-dependent induction of anxiogenic-like effects after central infusion of urocortin or corticotropin-releasing factor in the rat

    Rationale: Corticotropin-releasing factor (CRF) and urocortin (Ucn) belong to the CRF-related family, share a high degree of structural homology and bind to CRF receptors. However, compared with CRF, Ucn was show...

    M. Spina, E. Merlo-Pich, Y. Akwa, C. Balducci, A. Basso, E. Zorrilla… in Psychopharmacology (2002)

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    Article

    Highly controlled gene expression using combinations of a tissue-specific promoter, recombinant adenovirus and a tetracycline-regulatable transcription factor

    Controllable gene expression is a desirable feature both in gene therapy protocols and for the study of gene function in animals and plants. We have exploited the modular character of the tetracycline (tc)-reg...

    P Ghersa, R Pescini Gobert, P Sattonnet-Roche, CA Richards, E Merlo Pich… in Gene Therapy (1998)

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    Article

    Changes in glucocorticoid receptor immunoreactivity after adrenalectomy and corticosterone treatment in the rat testis

    The distribution of glucocorticoid receptor (GR) in the rat testis was investigated by means of immunocytochemistry (IR) and computer-assisted image analysis. A monoclonal antibody against rat liver GR showed ...

    G. Biagini, E. Merlo Pich, A. Frasoldati… in Journal of Endocrinological Investigation (1995)

  6. No Access

    Article

    Disinhibitory effects of buspirone and low doses of sulpiride and haloperidol in two experimental anxiety models in rats: Possible role of dopamine

    Low doses of buspirone, haloperidol and sulpiride were compared with diazepam in two experimental models of anxiety in rats. In a conflict test, 0.6 and 1.2 mg/kg buspirone, 0.05 and 0.10 mg/kg haloperidol and...

    E. Merlo Pich, R. Samanin in Psychopharmacology (1986)