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359 Result(s)
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Article
Three CAG Trinucleotide Repeats on Chromosome 6 (D6S1014, D6S1015, and D6S1058) Are Not Expanded in 30 Families with Schizophrenia
Since 1991, more than five neuro-genetic disorders have been recognized to be caused by trinucleotide repeat expansions, and the list of such diseases should grow. The diseases are characterized clinically by ...
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Article
Investigation of inducing effect of specific cytotoxicity of CTLS by antigen peptides from T lymphocytic leukemia cells
Objective: To investigate the characteristics of specific antitumor immunity induced by antigen peptides mixture from T lymphocytic leukemia cells. Method: Antigen peptides mixtures were prepared from differen...
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Article
Experimental study on effect of Compound Biejia Ruangan prescription on high-resolution computerized tomographic images in bleomycin induced pulmonary fibrosis rats
Objective: To study the therapeutic effect of Compound Biejia Ruangan prescription (CBRP) on rat model with pulmonary fibrosis induced by bleomycin.Methods: Fifty-four male Sprague-Dawley rats we...
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Open AccessA mass vaccination campaign targeting adults and children to prevent typhoid fever in Hechi; Expanding the use of Vi polysaccharide vaccine in Southeast China: A cluster-randomized trial
One of the goals of this study was to learn the coverage, safety and logistics of a mass vaccination campaign against typhoid fever in children and adults using locally produced typhoid Vi polysaccharide (PS) ...
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Long-term outcome of combined penetrating keratoplasty and vitreoretinal surgery using temporary keratoprosthesis
To evaluate the long-term outcome of combined penetrating keratoplasty (PKP) and vitreoretinal surgery using temporary keratoprosthesis (TKP).
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Article
Inhibition of Evoked Glutamate Release by Neurosteroid Allopregnanolone Via Inhibition of L-Type Calcium Channels in Rat Medial Prefrontal Cortex
Allopregnanolone is one of the most important neurosteroids in the brain. We studied the effect and mechanism of allopregnanolone on spontaneous and evoked glutamate release in the medial prefrontal cortex usi...
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Open AccessHuman prion disease with a G114V mutation and epidemiological studies in a Chinese family: a case series
Transmissible spongiform encephalopathies are a group of neurodegenerative diseases of humans and animals. Genetic Creutzfeldt-Jakob diseases, in which mutations in the PRNP gene predispose to disease by causing ...
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Open AccessSurveillance for Creutzfeldt-Jakob disease in China from 2006 to 2007
Human transmissible spongiform encephalopathies (HTSE), or Creutzfeldt-Jakob disease (CJD), is a group of rare and fatal diseases in central nervous system. Since outbreak of bovine spongiform encephalopathy (...
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Article
Open Access18. Arterial Stiffness in Geriatric Medicine
Aging exerts a number of deleterious changes in the cardiovascular system, and, in particular, on the large arteries. Previous studies have suggested that augmentation index (Aix) and aortic pulse wave velocit...
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Article
Open AccessObesity related methylation changes in DNA of peripheral blood leukocytes
Despite evidence linking obesity to impaired immune function, little is known about the specific mechanisms. Because of emerging evidence that immune responses are epigenetically regulated, we hypothesized tha...
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Article
Detection of global DNA methylation and paternally imprinted H19 gene methylation in preeclamptic placentas
Preeclampsia (PE) is a severe hypertensive disorder associated with pregnancy; despite substantial research effort in the past several years, the etiology of PE is still unclear. The role of epigenetic factors...
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Article
Factors associated with prevalence, awareness, treatment and control of hypertension in urban adults from 33 communities in China: the CHPSNE Study
Using a randomized multistage cluster sampling, we studied the factors associated with the prevalence, awareness, treatment and control of hypertension (defined as systolic and diastolic blood pressure (BP) me...
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Article
Effect of Yiqi Bufei Recipe (益气补肺方) on patients with pulmonary incompetence after pneumonectomy
To study the effect of Yiqi Bufei Recipe (益气补肺方, YBR) on surgical tolerability, pulmonary compensatory function and post-operation rehabilitation in patients with pulmonary incompetence (PI) after pneumonectomy.
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Open AccessPrevalence of low back pain and associated occupational factors among Chinese coal miners
Very few studies have evaluated the association between occupational factors and low back pain (LBP) among miners. The epidemiological data on LBP in Chinese miners are limited. The aim of this study was to me...
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Open AccessEpidemiology of general obesity, abdominal obesity and related risk factors in urban adults from 33 communities of northeast china: the CHPSNE study
Obesity increases the risk of many diseases. However, there has been little literature about the epidemiology of obesity classified by body mass index (BMI) or waist (abdominal obesity) among urban Chinese adu...
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Article
Associations between TCF4 Gene Polymorphism and Cognitive Functions in Schizophrenia Patients and Healthy Controls
The SNP rs2958182 was reported to be significantly associated with schizophrenia (SCZ) in Han Chinese. This study examined this SNP’s associations with cognitive functions in 580 SCZ patients and 498 controls....
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Open AccessEffects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study
Metabolomics helps to identify links between environmental exposures and intermediate biomarkers of disturbed pathways. We previously reported variations in phosphatidylcholines in male smokers compared with n...
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Article
Intrauterine growth restriction transiently delays alveolar formation and disrupts retinoic acid receptor expression in the lung of female rat pups
We showed that intrauterine growth restriction (IUGR) increases distal airspace wall thickness at birth (postnatal age 0; P0) in rat pups (saccular stage of lung development). However, that report did not asse...
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Article
Open AccessRoles of virulence genes (PsaA and CpsA) on the invasion of Streptococcus pneumoniae into blood system
Streptococcus pneumoniae (SP) is the major cause of childhood mortality worldwide, we need to understand virulence genes of SP so can better target the treatment.
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Prevalence, awareness, treatment and control of hypertension in elderly Chinese
We studied the prevalence, awareness, treatment and control of hypertension in an elderly Chinese population. The study subjects (age ⩾60 years) were recruited from a suburban town of Shanghai from 2006 to 200...