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Article
Risk factors for histologically confirmed benign breast tumors
A case-control study of 156 cases of various types of benign breast disease (BBD) and 156 population controls was conducted to investigate the role of various behavioral, reproductive, and hormonal factors in ...
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Article
Flavonol and Flavone Intake and the Risk of Intermittent Claudication in Male Smokers
The objective of this study was to investigate the association between flavonol and flavone intake and the risk of intermittent claudication in male smokers. The study population consisted of participants of t...
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Article
Short-term weight change and fluctuation as risk factors for type 2 diabetes in Finnish male smokers
Risk of weight change and fluctuation for type 2 diabetes was studied in a prospective study among 20,952 Finnish male smokers aged 50–69 years. Baseline data on lifestyle and medical history were collected, a...
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Article
Circulating 25-hydroxyvitamin D up to 3 decades prior to diagnosis in relation to overall and organ-specific cancer survival
While vitamin D has been associated with improved overall cancer survival in some investigations, few have prospectively evaluated organ-specific survival. We examined the accepted biomarker of vitamin D statu...
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Article
Relationship between chocolate consumption and overall and cause-specific mortality, systematic review and updated meta-analysis
Chocolate is a rich dietary source of various bioactive flavonoid compounds. Despite being one of the most popular foods worldwide, the association between chocolate consumption and long-term mortality remains...
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Article
Authors’ Reply: Relationship between chocolate consumption and overall and cause-specific mortality, systematic review and updated meta-analysis
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Article
Lipidomics and pancreatic cancer risk in two prospective studies
Pancreatic ductal carcinoma (PDAC) is highly fatal with limited understanding of mechanisms underlying its carcinogenesis. We comprehensively investigated whether lipidomic measures were associated with PDAC i...
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Article
Open AccessPartial substitution of red meat or processed meat with plant-based foods and the risk of colorectal cancer
Shifting from animal-based to plant-based diets could reduce colorectal cancer (CRC) incidence. Currently, the impacts of these dietary shifts on CRC risk are ill-defined. Therefore, we examined partial substi...
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Article
Open AccessA prospective study of smoking-related white blood cell DNA methylation markers and risk of bladder cancer
Bladder cancer, a common neoplasm, is primarily caused by tobacco smoking. Epigenetic alterations including DNA methylation have the potential to be used as prospective markers of increased risk, particularly ...