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Article
Open AccessThe projected health and economic impact of increased colorectal cancer screening participation among Canadians by income quintile
Disparities in colorectal cancer (CRC) screening uptake by socioeconomic status have been observed in Canada. We used the OncoSim-Colorectal model to evaluate the health and economic outcomes associated with i...
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Article
Time spent in the sun and the risk of develo** non-Hodgkin lymphoma: a Canadian cohort study
The objective was to explore the relationship of sun behavior patterns with the risk of develo** non-Hodgkin lymphoma (NHL).
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Article
Correction to: Lifestyle factors and lung cancer risk among never smokers in the Canadian Partnership for Tomorrow’s Health (CanPath)
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Article
Lifestyle factors and lung cancer risk among never smokers in the Canadian Partnership for Tomorrow’s Health (CanPath)
Although smoking is the primary risk factor for lung cancer, 15–25% of lung cancers occur in never smokers. Emerging evidence suggests lifestyle factors are associated with lung cancer risk, but few studies am...
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Article
Dietary patterns with combined and site-specific cancer incidence in Alberta’s Tomorrow Project cohort
Poor diet quality has been associated with an increased risk of cancer. Here, we examine the association between dietary patterns derived with two methods, and combined and site-specific cancer incidence in Ca...
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Article
Estimating the future cancer management costs attributable to modifiable risk factors in Canada
An estimated 33–37% of incident cancers in Canada are attributable to modifiable risk factors. Interventions targeting these risk factors would minimize the substantial health and economic burdens Canadians fa...
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Article
Estimates of future cancer mortality attributable to modifiable risk factors in Canada
Modifiable lifestyle, environmental, and infectious risk factors associated with cancer impact both cancer incidence and mortality at the population level. Most studies estimating this burden focus on cancer i...
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Examining the etiology of early-onset breast cancer in the Canadian Partnership for Tomorrow’s Health (CanPath)
Breast cancer incidence among younger women (under age 50) has increased over the past 25 years, yet little is known about the etiology among this age group. The objective of this study was to investigate rela...
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Article
The current burden of non-melanoma skin cancer attributable to ultraviolet radiation and related risk behaviours in Canada
Ultraviolet radiation (UVR) is an established cause of non-melanoma skin cancer (NMSC)—basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The aim of this study was to estimate the current burden of ...
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Article
High-sensitivity C-reactive protein, hemoglobin A1c and breast cancer risk: a nested case–control study from Alberta’s Tomorrow Project cohort
Our aim is to examine the associations between high-sensitivity C-reactive protein (hsCRP) and hemoglobin A1c (HbA1c), common biomarkers of inflammation and insulin resistance, respectively, with breast cancer...
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Article
The incidence of breast cancer in Canada 1971–2015: trends in screening-eligible and young-onset age groups
Breast cancer incidence has fluctuated considerably in Canada, with recent reductions in rates among screening-eligible women. However, incidence of early-onset and pre-menopausal breast cancer is understudied...
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Article
Case–control study of endogenous sex steroid hormones and risk of endometrial cancer
Epidemiologic evidence regarding the role of endogenous sex hormones in endometrial cancer etiology remains inconsistent. The objective of this study was to investigate if circulating levels of endogenous estr...
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Article
The individual and combined effects of alcohol consumption and cigarette smoking on site-specific cancer risk in a prospective cohort of 26,607 adults: results from Alberta’s Tomorrow Project
Alcohol consumption and cigarette smoking increase the risk of develo** several cancers. We examined the individual and synergistic effects of these modifiable lifestyle factors on overall and site-specific ...
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Article
The association between sleep duration and cancer-specific mortality: a systematic review and meta-analysis
In this systematic review and meta-analysis, we aimed to estimate cancer-specific mortality and all-cause mortality among cancer survivors associated with both short (typically 5 or 6 h/night) and long (typica...
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Article
Indoor tanning and the risk of develo** non-cutaneous cancers: a systematic review and meta-analysis
Despite a strong association between indoor tanning and the risk of cutaneous cancers, the relationship between indoor tanning and non-cutaneous cancers is unknown. Our objective was to estimate the associatio...
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Article
Open AccessMeasures of excess body weight and anthropometry among adult Albertans: cross-sectional results from Alberta’s tomorrow project cohort
Excess body weight during adulthood has been consistently associated with all-cause mortality, cardiovascular disease, and cancer at multiple sites among other chronic diseases. We describe the prevalence of e...
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Article
Open AccessBreast cancer survival among young women: a review of the role of modifiable lifestyle factors
Almost 7 % of breast cancers are diagnosed among women age 40 years and younger in Western populations. Clinical outcomes among young women are worse. Early age-of-onset increases the risk of contralateral br...
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Article
Physical activity and risk of pancreatic cancer in a central European multicenter case–control study
Findings from epidemiological studies examining physical activity in relation to pancreatic cancer risk have suggested decreased risks for physical activity; however, the results are inconsistent.
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Article
Aspirin and NSAID use and lung cancer risk: a pooled analysis in the International Lung Cancer Consortium (ILCCO)
To investigate the hypothesis that non-steroidal anti-inflammatory drugs (NSAIDs) lower lung cancer risk.