4 Result(s)
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Article
Cynthia Shannon Weickert
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessIdentifying gene expression profiles associated with neurogenesis and inflammation in the human subependymal zone from development through aging
The generation of new neurons within the mammalian forebrain continues throughout life within two main neurogenic niches, the subgranular zone (SGZ) of the hippocampal dentate gyrus, and the subependymal zone ...
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Open AccessEffect of Immune Activation during Early Gestation or Late Gestation on Inhibitory Markers in Adult Male Rats
People with schizophrenia exhibit deficits in inhibitory neurons and cognition. The timing of maternal immune activation (MIA) may present distinct schizophrenia-like phenotypes in progeny. We investigated whe...
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Open AccessElevated ubiquitinated proteins in brain and blood of individuals with schizophrenia
Dysregulation of the ubiquitin proteasome system (UPS) has been linked to schizophrenia but it is not clear if this dysregulation is detectable in both brain and blood. We examined free mono-ubiquitin, ubiquit...
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Article
Open AccessDysregulation of glucocorticoid receptor co-factors FKBP5, BAG1 and PTGES3 in prefrontal cortex in psychotic illness
Molecular abnormalities within the glucocorticoid receptor (GR) stress signaling pathway may confer, or reflect, susceptibility to stress in schizophrenia and bipolar disorder, but the extent of such abnormali...
