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Article
Open AccessAssociation of FOXJ1 polymorphisms with systemic lupus erythematosus and rheumatoid arthritis in Korean population
The forkhead-box J1 (FOXJ1) transcription factor could suppress a spontaneous activation of T cells and B cells through an induction of IκBβ that results in repression of NF-κB activity. In Foxj1 deficiency mi...
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Article
Identification of polymorphisms in human interleukin-27 and their association with asthma in a Korean population
Interleukin 27 (IL-27) acts as a versatile cytokine in the early regulation of Th1 initiation and in the negative regulation of the Th2 factor GATA-3. IL-27, which was discovered as a novel heterodimeric cytok...
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Article
Open AccessAnalysis of the variations in IL-28RA gene and their association with allergic rhinitis
IL-28RA is one of the important candidate genes for complex trait of genetic diseases, but there is no published information of the genetic variation in this gene. We scanned the seven exons and their boundary...
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Article
Identification of single nucleotide polymorphisms in FOXJ1 and their association with allergic rhinitis
Forkhead-box J1 (FOXJ1) is a presumed transcription factor that can suppress T cell activity, at least partially, through the repression of NFκB activity. Thus, dysregulation of FOXJ1 is thought to be associated ...