7 Result(s)
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Article
Chuan Yi Tang
Computer Appl. in Life Sciences
Microarrays
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Article
Open AccessClover: a clustering-oriented de novo assembler for Illumina sequences
Next-generation sequencing technologies revolutionized genomics by producing high-throughput reads at low cost, and this progress has prompted the recent development of de novo assemblers. Multiple assembly me...
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Article
Open AccessReconstruction of phyletic trees by global alignment of multiple metabolic networks
In the last decade, a considerable amount of research has been devoted to investigating the phylogenetic properties of organisms from a systems-level perspective. Most studies have focused on the classificatio...
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Article
Open AccessA novel method to identify cooperative functional modules: study of module coordination in the Saccharomyces cerevisiae cell cycle
Identifying key components in biological processes and their associations is critical for deciphering cellular functions. Recently, numerous gene expression and molecular interaction experiments have been repo...
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Article
Open AccessA genetic algorithm-based boolean delay model of intracellular signal transduction in inflammation
Signal transduction is the major mechanism through which cells transmit external stimuli to evoke intracellular biochemical responses. Understanding relationship between external stimuli and corresponding cell...
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Open AccessComputational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-κB signaling-induced gene expression responses in inflammation
Signal transduction is the major mechanism through which cells transmit external stimuli to evoke intracellular biochemical responses. Diverse cellular stimuli create a wide variety of transcription factor act...
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Article
Open AccessA parallel and incremental algorithm for efficient unique signature discovery on DNA databases
DNA signatures are distinct short nucleotide sequences that provide valuable information that is used for various purposes, such as the design of Polymerase Chain Reaction primers and microarray experiments. B...
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Open AccessA reinforced merging methodology for map** unique peptide motifs in members of protein families
Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (3-D) structures. However, enzymes with hig...
