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Diffusion-weighted imaging improves prediction in cognitive outcome and clinical phases in patients with carbon monoxide intoxication

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  1. Article

    Open Access

    Genetic effect of interleukin-1 beta (C-511T) polymorphism on the structural covariance network and white matter integrity in Alzheimer’s disease

    Inflammatory processes play a pivotal role in the degenerative process of Alzheimer’s disease. In humans, a biallelic (C/T) polymorphism in the promoter region (position-511) (rs16944) of the interleukin-1 bet...

    Chi-Wei Huang, Shih-Wei Hsu, Shih-Jen Tsai, Nai-Ching Chen… in Journal of Neuroinflammation (2017)

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  2. Article

    Open Access

    Associations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer’s disease

    Alzheimer’s disease (AD) is a complex neurodegenerative disease, and genetic differences may mediate neuronal degeneration. In humans, a single-nucleotide polymorphism in the B-cell chronic lymphocytic leukemi...

    Chiung-Chih Chang, Ya-Ting Chang, Chi-Wei Huang… in Alzheimer's Research & Therapy (2018)

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  3. Article

    Open Access

    Catechol-O-Methyltransferase Val158Met Polymorphism on Striatum Structural Covariance Networks in Alzheimer’s Disease

    The catechol-O-methyltransferase enzyme metabolizes dopamine in the prefrontal axis, and its genetic polymorphism (rs4680; Val158Met) is a known determinant of dopamine signaling. In this study, we investigate...

    Chiung-Chih Chang, Shih-Jen Tsai, Nai-Ching Chen, Chi-Wei Huang… in Molecular Neurobiology (2018)

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  4. Article

    Open Access

    ABCA7 polymorphisms correlate with memory impairment and default mode network in patients with APOEε4-associated Alzheimer’s disease

    Since both APOE and ABCA7 protein expression may independently reduce neuritic plaque burden and reorganize fibrillar amyloid burden-mediated disruption of functional connectivity in the default mode network, we ...

    Ya-Ting Chang, Shih-Wei Hsu, Shu-Hua Huang, Chi-Wei Huang… in Alzheimer's Research & Therapy (2019)

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