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  1. Article

    Publisher Correction: The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells

    Sumit Sen Santara, Dian-Jang Lee, Ângela Crespo, Jun Jacob Hu, Caitlin Walker in Nature (2023)

  2. No Access

    Article

    The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells

    Natural killer (NK) cells kill infected, transformed and stressed cells when an activating NK cell receptor is triggered1. Most NK cells and some innate lymphoid cells express the activating receptor NKp46, encod...

    Sumit Sen Santara, Dian-Jang Lee, Ângela Crespo, Jun Jacob Hu, Caitlin Walker in Nature (2023)

  3. Article

    FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation

    SARS-CoV-2 can cause acute respiratory distress and death in some patients1. Although severe COVID-19 is linked to substantial inflammation, how SARS-CoV-2 triggers inflammation is not clear2. Monocytes and macro...

    Caroline Junqueira, Ângela Crespo, Shahin Ranjbar, Luna B. de Lacerda in Nature (2022)

  4. Article

    Inflammasome activation in infected macrophages drives COVID-19 pathology

    Severe COVID-19 is characterized by persistent lung inflammation, inflammatory cytokine production, viral RNA and a sustained interferon (IFN) response, all of which are recapitulated and required for patholog...

    Esen Sefik, Rihao Qu, Caroline Junqueira, Eleanna Kaffe, Haris Mirza, Jun Zhao in Nature (2022)

  5. Article

    Open Access

    Author Correction: Caspase-8 mediates inflammation and disease in rodent malaria

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Larissa M. N. Pereira, Patrícia A. Assis, Natalia M. de Araújo in Nature Communications (2020)

  6. Article

    Open Access

    Caspase-8 mediates inflammation and disease in rodent malaria

    Earlier studies indicate that either the canonical or non-canonical pathways of inflammasome activation have a limited role on malaria pathogenesis. Here, we report that caspase-8 is a central mediator of syst...

    Larissa M. N. Pereira, Patrícia A. Assis, Natalia M. de Araújo in Nature Communications (2020)

  7. No Access

    Article

    Gasdermin E suppresses tumour growth by activating anti-tumour immunity

    Cleavage of the gasdermin proteins to produce pore-forming amino-terminal fragments causes inflammatory cell death (pyroptosis)1. Gasdermin E (GSDME, also known as DFNA5)—mutated in familial ageing-related hearin...

    Zhibin Zhang, Ying Zhang, Shiyu **a, Qing Kong, Shunying Li, **ng Liu in Nature (2020)