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  1. No Access

    Article

    Detection of engraftment and mixed chimerism following bone marrow transplantation using PCR amplification of a highly variable region-variable number of tandem repeats (VNTR) in the von Willebrand factor gene

    Detection of host cells in peripheral blood and/or bone marrow (mixed chimerism) of patients who have undergone bone marrow transplantation (BMT) is possible using either immunological methods or cytogenetic o...

    A. Gaiger, C. Mannhalter, W. Hinterberger, O. Haas, C. Marosi… in Annals of Hematology (1991)

  2. Article

    Abstract

    Ch. Mache, Ch. Urban, H. Sauer, G. Brandesky, H. Meßner… in Annals of Hematology (1992)

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  3. No Access

    Article

    Kinetics of minimal residual disease during induction/consolidation therapy in standard-risk adult B-lineage acute lymphoblastic leukemia

    We have compared the kinetics of minimal residual disease (MRD) by simultaneous polymerase chain reaction (PCR) monitoring with oligonucleotides for the immunoglobulin heavy chain (IgH) complementarity-determi...

    C. Scholten, M. Födinger, M. Mitterbauer, K. Laczika… in Annals of Hematology (1995)

  4. No Access

    Article

    Long-term leukemia-free survival after allogeneic marrow transplantation in patients with acute myelogenous leukemia

    Between February 1982 and April 1995, 62 patients (37 male, 25 female) with acute myelogenous leukemia (AML) with a median age of 32 years (19–51 years) received allogeneic marrow grafts from an HLA-identical ...

    H. T. Greinix, F. Keil, S. A. Brugger, E. Reiter, W. Linkesch… in Annals of Hematology (1996)

  5. No Access

    Article

    FLAG (fludarabine, cytosine arabinoside, G-CSF) for refractory and relapsed acute myeloid leukemia

     Twenty-two patients with refractory or relapsed AML were treated with FLAG [25 mg/m2 fludarabine daily (days 1–5), 2 g/m2 daily Ara-C (days 1–5) and 400 μg/m2 daily G-CSF (day -1 till the absolute neutrophil cou...

    I.-M. Huhmann, H. H. Watzke, K. Geissler, H. Gisslinger, U. Jäger… in Annals of Hematology (1996)

  6. No Access

    Article

    Prognostic significance of WT1 gene expression at diagnosis in adult de novo acute myeloid leukemia

    We examined the presence of WT1-specific mRNA in bone marrow samples of 125 patients with de novo acute myeloid leukemia at diagnosis by two-step RT-PCR. The sensitivity of the assay was 1:100 (first step) and 1:...

    D Schmid, G Heinze, B Linnerth, K Tisljar, R Kusec, K Geissler, C Sillaber… in Leukemia (1997)

  7. No Access

    Article

    Leukemia-free survival and mortality in patients with refractory or relapsed acute leukemia given marrow transplants from sibling and unrelated donors

    Between April 1982 and February 1997 39 patients (24 male, 15 female) with refractory acute leukemia and a median age of 31 years (19–51 years) received allogeneic marrow grafts from an HLA-identical sibling (n =...

    HT Greinix, E Reiter, F Keil, G Fischer, K Lechner… in Bone Marrow Transplantation (1998)

  8. No Access

    Article

    Hypofibrinogenemia in non-M3 acute myeloid leukemia. Incidence, clinical and laboratory characteristics and prognosis

    Among 379 patients with AML with FAB type M1, 2 and M4–7 diagnosed between 1978 and 1997 in our institution, 19 (5%) had hypofibrinogenemia (HF), ie a fibrinogen level <180 mg/dl. compared to patients with nor...

    A Weltermann, I Pabinger, K Geissler, U Jäger, H Gisslinger, P Knöbl… in Leukemia (1998)

  9. No Access

    Article

    Graft-versus-host disease following second syngeneic stem cell transplantation for relapsed chronic myeloid leukemia

     Allogeneic bone marrow transplantation is the only curative treatment for patients with Philadelphia chromosome-positive chronic myeloid leukemia (CML); however, recurrence of disease remains a major cause of...

    E. Reiter, H. T. Greinix, G. Mitterbauer, G. Fischer, F. Keil… in Annals of Hematology (1998)

  10. No Access

    Article

    Detection of the WT1 transcript by RT-PCR in complete remission has no prognostic relevance in de novo acute myeloid leukemia

    The WT1 gene is expressed in 73–100% of patients with acute myelogenous leukemia (AML) and is thought to play a role in maintaining the viability of leukemic cells. WT1 has been proposed as a marker for minima...

    A Gaiger, D Schmid, G Heinze, B Linnerth, H Greinix, P Kalhs, K Tisljar… in Leukemia (1998)

  11. No Access

    Article

    Low transplant-related mortality in patients receiving unrelated donor marrow grafts for leukemia

    Transplantation with unrelated donor (UD) marrow has been shown to potentially cure patients with leukemia. Between January 1991 and April 1998, 54 patients with leukemia have received an UD BMT at our institu...

    P Kalhs, S Brugger, E Reiter, F Keil, G Fischer… in Bone Marrow Transplantation (1999)

  12. No Access

    Article

    Genetic fingerprinting in mouthwashes of patients after allogeneic bone marrow transplantation

    Detection of chimerism by PCR analysis of short tandem repeats (STR) in blood samples of patients who received allogeneic bone marrow transplantation (BMT) has proved to be an important method for early detect...

    G Endler, H Greinix, K Winkler, G Mitterbauer, C Mannhalter in Bone Marrow Transplantation (1999)

  13. No Access

    Article

    Hematopoietic donor chimerism and graft-versus-myeloma effect in relapse of multiple myeloma after allogeneic bone marrow transplantation

     A large group of patients relapsing after allogeneic bone marrow transplantation (BMT) have obtained remission after infusion of leukocytes from their original donor, suggesting a graft-versus-myeloma effect....

    F. Keil, P. Kalhs, X. Chen, O. A. Haas, G. Fritsch, A. Chott… in Annals of Hematology (1999)

  14. No Access

    Article

    Monitoring of minimal residual leukemia in patients with MLL-AF9 positive acute myeloid leukemia by RT-PCR

    Twenty-seven patients with AML and MLL gene rearrangement were analyzed by a reverse transcriptase polymerase chain reaction (RT-PCR) for the MLL-AF9 translocation. The MLL-AF9 fusion transcript was detected in s...

    G Mitterbauer, C Zimmer, C Fonatsch, OA Haas, R Thalhammer-Scherrer… in Leukemia (1999)

  15. No Access

    Article

    Long-term follow-up of patients after related- and unrelated-donor bone marrow transplantation for chronic myelogenous leukemia

     Between January 1983 and December 1997, 88 patients (36 female, 52 male, median age 37 years, range 19–57) with chronic myelogenous leukemia (CML) underwent allogeneic bone marrow transplantation (BMT) at the...

    E. Reiter, H. T. Greinix, F. Keil, S. Brugger, W. Rabitsch… in Annals of Hematology (1999)

  16. No Access

    Article

    Excellent disease eradication by myeloablative therapy and stem-cell transplantation in patients with acute myelogenous leukemia

     Between February 1982 and 1999, 118 consecutive patients (65 male, 53 female) with acute myelogenous leukemia (AML), with a median age of 35 years (range 17–56 years), received stem-cell grafts from a human l...

    H. T. Greinix, H. Loidolt, W. Rabitsch, A. Schulenburg, F. Keil… in Annals of Hematology (2000)

  17. No Access

    Article

    Evaluation of a highly specific functional test for the detection of factor V Leiden

    In the present study, a new functional test for the detection of increased resistance of coagulation factor V to degradation by activated protein C (factor V Leiden mutation) was evaluated. The STA-STACLOT APC...

    P. Quehenberger, S. Handler, C. Mannhalter… in International Journal of Clinical and Labo… (2000)

  18. No Access

    Article

    Treatment of leukemic relapse after allogeneic stem cell transplantation with cytotoreductive chemotherapy and/or immunotherapy or second transplants

    We analyzed toxicity and efficacy of chemotherapy (CT) or second stem cell transplantation (SCT) and/or immunotherapy defined as stop of immunosuppression (IS) or donor leukocyte infusion (DLI) in 47 patients ...

    F Keil, E Prinz, P Kalhs, K Lechner, K Moser, I Schwarzinger, U Jäger… in Leukemia (2001)

  19. No Access

    Article

    Long-term clinical and molecular remission after allogeneic stem cell transplantation (SCT) in patients with poor prognosis non-Hodgkin's lymphoma

    From 1987 to 1999 35 patients with poor prognosis non-Hodgkin's lymphoma (NHL) underwent allogeneic stem cell transplantation (SCT) at the University Hospitals of Vienna and Graz. Initial biopsy specimens were...

    M Mitterbauer, P Neumeister, P Kalhs, S Brugger, G Fischer, K Dieckmann… in Leukemia (2001)

  20. No Access

    Article

    Alternative end-joining in follicular lymphomas’ t(14;18) translocation

    T(14;18) chromosomal translocation is assumed to result from illegitimate rearrangement between the BCL2 proto-oncogene and the IGH locus during the DH to JH joining phase of V(D)J recombination in early B cells....

    R Marculescu, T Le, S Böcskör, G Mitterbauer, A Chott, C Mannhalter, U Jaeger… in Leukemia (2002)

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