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    Article

    Population pharmacokinetics and pharmacodynamics of efmarodocokin alfa (IL-22Fc)

    Efmarodocokin alfa (IL-22Fc) is a fusion protein of human IL-22 linked to the crystallizable fragment (Fc) of human IgG4. It has been tested in multiple indications including inflammatory bowel disease (IBD). ...

    Yanke Yu, Michael E. Rothenberg in Journal of Pharmacokinetics and Pharmacody… (2024)

  2. Article

    Open Access

    B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin

    B-lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL) are members of the tumor necrosis factor (TNF) family that regulate B-cell maturation, survival, and function. They are overexpressed ...

    Stacey R Dillon, Brandon Harder, Kenneth B Lewis in Arthritis Research & Therapy (2010)

  3. Article

    Erratum: Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice

    Nature Immunology 5, 752–760 (2004). The published version of this article failed to include the microarray accession numbers. They are listed here: Geo microarray accession numbers. GSE1304, Control and Il31 ...

    Stacey R Dillon, Cindy Sprecher, Angela Hammond, Janine Bilsborough in Nature Immunology (2005)

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    Article

    Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice

    T cell–derived cytokines are important in the development of an effective immune response, but when dysregulated they can promote disease. Here we identify a four-helix bundle cytokine we have called interleuk...

    Stacey R Dillon, Cindy Sprecher, Angela Hammond, Janine Bilsborough in Nature Immunology (2004)