1 Result(s)

Article

GNE-493 inhibits prostate cancer cell growth via Akt-mTOR-dependent and -independent mechanisms

GNE-493 is a novel PI3K/mTOR dual inhibitor with improved metabolic stability, oral bioavailability, and excellent pharmacokinetic parameters. Here GNE-493 potently inhibited viability, proliferation, and migr...

Lu **, Wei Zhang, Ming-Yu Yao, Ye Tian, Bo-xin Xue, Wei Tao in Cell Death Discovery (2022)