15 Result(s)
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Article
Andrew Thamboo
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Article
Effect of Body Weight on Response to Nasal Glucocorticoid Treatment in Allergic Rhinitis
Allergic rhinitis is among the most common chronic diseases in the world. Obesity can lead to a chronic systemic inflammatory process. In this study, we evaluated the effects of body weight on the response to ...
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Open AccessQuantifying surgical completeness in patients with aspirin exacerbated respiratory disease
Aspirin exacerbated respiratory disease (AERD) in patients who have had sinus surgery remains a management challenge. Aspirin desensitization and biologics are additional treatment options. It remains unclear ...
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Open AccessCost-effectiveness analysis of biologics for the treatment of chronic rhinosinusitis with nasal polyps in Canada
Dupilumab, omalizumab, and mepolizumab are the three biologics currently approved for use in CRSwNP in Canada. Despite evidence of efficacy, their cost-effectiveness, which is a key factor influencing prescrib...
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Upper Airway Mucociliary Clearance is Impaired in Dyspneic COVID-19 Patients
Covid-19 is transmitted mainly by respiratory droplets and as the upper airway mucosa is the first innate immune barrier, it is crucial to understand the effects of SARS-CoV-2 on this system. In the current st...
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Differential Angiogenic Induction Impacts Nasal Polyp Tissue Growth
In chronic rhinosinusitis with nasal polyps, inflammatory edema drives tissue remodeling favoring anomalous growth of the nasal mucosa, but a proangiogenic contribution of nasal polyp in support of tissue gro...
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Open AccessImproving predictability of IgE-high type 2 chronic sinusitis with nasal polyps in the biologic era
Chronic rhinosinusitis (CRS) is an inflammatory disease that may require biological therapy. Omalizumab is an anti-IgE biologic that was recently approved by the FDA and Health Canada for use in severe CRS wit...
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The Inferior Turbinate: Role in Normal Respiration and Airway Obstruction
The understanding of the inferior turbinate (IT) function, role in nasal obstruction, and its management for symptomatic relief has evolved. We aim to provide a comprehensive review of the anatomy, contributio...
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Open AccessVirtual Care in Rhinology
The SARS-CoV-2 (COVID) pandemic has resulted in an increase in virtual care. While some specialties are well suited to virtual care, Otolaryngology – Head and Neck Surgery could be limited due to reliance on p...
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Open AccessCanadian Rhinology Working Group consensus statement: biologic therapies for chronic rhinosinusitis
Recent evidence suggests that biologic therapy with targeted activity within the Type 2 inflammatory pathway can improve the clinical signs and symptoms of chronic rhinosinusitis with nasal polyposis (CRSwNP)....
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Open Access5-year outcomes of salvage endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma
Recurrent nasopharyngeal carcinoma (rNPC) can be salvaged with re-irradiation, open nasopharyngectomy, and more recently endoscopic nasopharyngectomy. However, long-term outcomes of endoscopic approaches are l...
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Open AccessCSO (Canadian Society of Otolaryngology - Head & Neck Surgery) position paper on rhinologic and skull base surgery during the COVID-19 pandemic
Healthcare services in many countries have been partially or completely disrupted by the Coronavirus (COVID-19) pandemic since its onset in the end of 2019. Amongst the most impacted are the elective medical a...
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Open AccessClinical evidence based review and recommendations of aerosol generating medical procedures in otolaryngology – head and neck surgery during the COVID-19 pandemic
Aerosol generating medical procedures (AGMPs) present risks to health care workers (HCW) due to airborne transmission of pathogens. During the COVID-19 pandemic, it is essential for HCWs to recognize which pro...
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Open AccessClinical evidence based review and systematic scientific review in the identification of malignant transformation of inverted papilloma
Inverted papilloma (IP) is an unusual type of benign tumor that has high recurrence rates and the potential to transform into squamous cell carcinomas (SCC). The mechanism of the transformation process from IP...
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Advances in Surgery for Chronic Rhinosinusitis
Our understanding of chronic rhinosinusitis (CRS) is always evolving with new concepts and technological advancements in order to achieve the best surgical outcomes.
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Potential risk factors associated with the development of synechiae following functional endoscopic sinus surgery
Synechiae formation in the middle meatus is the most common complication of functional endoscopic sinus surgery (FESS). Our objectives were to determine the incidence of synechiae occurring in a cohort of pati...
