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  1. Article

    Open Access

    Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24

    Thousands of human small and alternative open reading frames (smORFs and alt-ORFs, respectively) have recently been annotated. Many alt-ORFs are co-encoded with canonical proteins in multicistronic configurati...

    **ongwen Cao, Alexandra Khitun, Yang Luo, Zhenkun Na in Nature Communications (2021)

  2. No Access

    Article

    The translation of non-canonical open reading frames controls mucosal immunity

    The annotation of the mammalian protein-coding genome is incomplete. Arbitrary size restriction of open reading frames (ORFs) and the absolute requirement for a methionine codon as the sole initiator of transl...

    Ruaidhrí Jackson, Lina Kroehling, Alexandra Khitun, Will Bailis, Abigail Jarret in Nature (2018)