53 Result(s)

Article

Fate of Homologous Adult Spleen Cells injected into New-born Mice

DURING a series of experiments involving radiation chimæras, it became increasingly evident that it would be necessary to consider the results in terms of immunological tolerance of the actively acquired type....

A. J. S. DAVIES, SHEILA M. A. DOAK in Nature (1960)

Article

Anaemia Associated with the NK/Lymphoma in Mice

A J S Davies, A M Cross, K Lapis in British Journal of Cancer (1962)

Article

Attempted Tumour Therapy Complicated by a Viroid Associate of the Tumour

K Lapis, A J S Davies in British Journal of Cancer (1962)

Article

Establishment and Stability of Chimerism between Two Closely Related Lines of Mice

THE Medical Research Council Radiobiology Unit at Harwell recently developed a strain of CBA mice containing the T6 marker chromosomes^3,4. They kindly sent a breeding unit to the Chester Beatty Research Institute...

A. J. S. DAVIES, SHEILA M. A. DOAK, ELIZABETH LEUCHARS in Nature (1963)

Article

Time of Action of the Thymus in the Irradiated Adult Mouse

RECENT interest in the thymus has derived largely from the discovery that in both neonatally thymectomized and thymoctomized irradiated adult mice the development of the ability to respond to primary antigenic...

A. MARJORIE CROSS, A. J. S. DAVIES, BARBARA DOE, ELIZABETH LEUCHARS in Nature (1964)

Article

Thymus Grafts in Thymectomized and Normal Mice

EXPERIMENTS carried out on cytologically marked normal F₁ recipients implanted with a thymus from a newborn donor of the parental type have shown that cellular traffic from the host to the thymus graft can take p...

E. LEUCHARS, A. MORGAN, A. J. S. DAVIES, V. J. WALLIS in Nature (1967)

Article

Inactivation of Thymus Cells after Multiple Injections of Antigen

CELLS from a thymus graft are capable of proliferating in response to certain antigenic stimuli but are apparently incapable of producing antibody¹, and it has been suggested that these cells, here referred to as...

R. K. GERSHON, V. WALLIS, A. J. S. DAVIES, E. LEUCHARS in Nature (1968)

Article

Mode of Action for Anti-lymphocyte Serum

Recovery of the immune response both to sheep red blood cells and to skin homografts in mice treated with anti-lymphocyte serum is thymus-dependent. One result of this treatment is that thymus-derived cells ar...

E. LEUCHARS, V. J. WALLIS, A. J. S. DAVIES in Nature (1968)

Article

The thymus humoral factor under scrutiny

A. J. S. Davies in Agents and Actions (1969)

Article

Cellular Deficit in Thymectomized Mice

FOR the immune response to take place different types of cell must interact^1–3. Two populations of mouse spleen cells, both of which are required for the in vitro response to sheep erythrocytes, can be separated ...

D. E. MOSIER, F. W. FITCH, D. A. ROWLEY, A. J. S. DAVIES in Nature (1970)

Article

Chimaerism after Introduction of Lymphocytes into Normal Mice

THE lymphocyte population of mice can be thought to consist of at least two cell types¹, of which one, the T cell², derives from the thymus and which seems to be the only type of cell which can divide in response...

M. J. DOENHOFF, A. J. S. DAVIES, E. LEUCHARS, V. WALLIS in Nature (1970)

Article

Immune Responses

Cellular Immunology

A. J. S. DAVIES in Nature (1971)

Article

Pre-emption in Immunity

IN a series of experiments designed to explore the cellular basis of immunological tolerance¹, it was discovered that the response of the draining lymph nodes of mice to a subcutaneous injection of sheep red bloo...

C. M. O'TOOLE, A. J. S. DAVIES in Nature (1971)

Article

Immune Machinery

Immune Surveillance: Perspectives in Immunology

A. J. S. DAVIES in Nature (1971)

Article

Requirement of Thymus-dependent Lymphocytes for Potentiation by Adjuvants of Antibody Formation

THE mode of action of immunological adjuvants is of theoretical as well as practical importance. Adjuvants can not only increase immune responses; they can also bring about change from one type of immune respo...

A. C. ALLISON, A. J. S. DAVIES in Nature (1971)