8 Result(s)
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Article
Genetic polymorphism and high detrimental load in natural populations of Drosophila melanogaster from cellar and vineyard
Two Spanish natural populations of Drosophila melanogaster have been analysed with respect to genetic variability in third chromosome viability. The two populations, although from the same locality, belong to rel...
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Article
Chromosomal polymorphism and patterns of viability in natural populations of Drosophila melanogaster from cellar and vineyard
Two neighbouring natural populations of Drosophila melanogaster have been analysed, one from a cellar habitat and the other from a vineyard outside. An extensive study of inversion polymorphism in the two populat...
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Article
Laboratory approach to mitochondrial diseases
Dysfunction in mitochondrial processes has been related to several pathologies. In these disorders, the cell suffers oxidative imbalance that is mostly due to defects in pyruvate metabolism, mitochondrial fatt...
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Article
Participation of mitochondria in calcium signalling in the exocrine pancreas
This minireview is an attempt to put together some of the recent advances regarding the implications of mitochondria in Ca2+ homeostasis. Although the main role of this cytoplasmic organelle is ATP supply to the ...
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Article
Does nitric oxide play a role in maternal tolerance towards the foetus?
In pregnancy there occurs maternal tolerance to the foetus. Several mechanisms have been proposed to explain this phenomenon. The main immune population in the decidua are macrophages and natural killer cells,...
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Article
Production of nitric oxide and self-nitration of proteins during monocyte differentiation to dendritic cells
Nitric oxide (NO) can stimulate dendritic cells to a more activated state. However, nitric oxide and peroxynitrites production by dendritic cells has been usually associated with pathological situations such a...
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Article
Open AccessInhibitory effects of pharmacological doses of melatonin on aromatase activity and expression in rat glioma cells
Melatonin exerts oncostatic effects on different kinds of neoplasias, especially on oestrogen-dependent tumours. Recently, it has been described that melatonin, on the basis of its antioxidant properties, inhi...
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Article
Open AccessMelatonin inhibits aromatase promoter expression by regulating cyclooxygenases expression and activity in breast cancer cells
Melatonin reduces the development of breast cancer interfering with oestrogen-signalling pathways, and also inhibits aromatase activity and expression. Our objective was to study the promoters through which me...
