![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
The Abiotic Formation of Hydrocarbons from Dissolved CO2 Under Hydrothermal Conditions with Cobalt-Bearing Magnetite
Conversion of CO2 to organic compounds in hydrothermal systems is important in understanding prebiotic chemical evolution leading to the origin of life. However, organic compounds with carbon number of more than ...
-
Article
Ultrastructural evidence for iron accumulation within the tube of Vestimentiferan Ridgeia piscesae
This study reports on the accumulation of iron within the tube wall of the deep sea vent macro invertebrate Vestimentiferan Ridgeia piscesae collected from Juan de Fuca ridge. Combining an array of approaches inc...
-
Article
Salt-induced expression of genes related to Na+/K+ and ROS homeostasis in leaves of salt-resistant and salt-sensitive poplar species
Using the Affymetrix poplar genome array, we explored the leaf transcriptome of salt-tolerant Populus euphratica Oliv. and salt-sensitive P. popularis 35-44 (P. popularis) under control and saline conditions. Our...
-
Article
Construction of a recombinant human FGF1 expression vector for mammary gland-specific expression in human breast cancer cells
Human Fibroblast growth factor 1 (FGF1) has been recognized as a valuable protein drug for the treatment of many diseases because of its multiple functions in regulating a variety of biological processes invol...
-
Article
Neuroprotection against cobalt chloride-induced cell apoptosis of primary cultured cortical neurons by salidroside
Salidroside, a phenol glycoside of plant origin, has been documented to possess a broad spectrum of pharmacological properties, including protective effects against neuronal death induced by different insults....
-
Article
Identification of Differentially Expressed Genes in Lung Tissues of Nickel-Exposed Rats Using Suppression Subtractive Hybridization
Occupational exposure to nickel compound, such as nickel refining, electroplating, and in conjunction with other metals, is harmful to the health, causing respiratory distress, and lung and nasal cancer. In th...
-
Article
Impact of bifunctional chelators on biological properties of 111In-labeled cyclic peptide RGD dimers
The present study describes the synthesis and biological evaluation of 111In(DOTA-3P-RGD2) (DOTA = 1,4,7,10-tetraazacyclo-dodecane-1,4,7,10-tetraacetic acid; 3P-RGD2 = PEG4-E[PEG4-c(RGDfK)]2; PEG4 = 15-amino-4,7,...
-
Article
Molecular characterization of β-lactam-resistant Escherichia coli isolated from Fu River, China
The present study aims to demonstrate the β-lactam resistance phenotypes and genotypes of Escherichia coli isolates from the Fu River in Chengdu, southwestern China. We obtained 108 E. coli isolates from nine sam...
-
Article
A single nucleotide polymorphism at the Vrn-D1 promoter region in common wheat is associated with vernalization response
Facultative wheat varieties adapt to a particular environment. But the molecular basis for the facultative growth habit is not clear relative to winter and spring growth habit. Two sets of wheat varieties were...
-
Article
Isolation and Characterization of a Novel Noncoding RNA from Nickel-Induced Lung Cancer
Noncoding RNAs have drawn significant attention in carcinogenesis. In this study, we identified a novel gene named nickel-related gene1 (NRG1) associated with nickel-induced cancer. By using rapid amplificatio...
-
Article
The Alteration of MiR-222 and Its Target Genes in Nickel-Induced Tumor
Nickel is an important kind of metal and a necessary trace element in people’s production and livelihood; it is also a well-confirmed human carcinogen. In the past few years, researchers did a large number of ...
-
Article
Effects of wet and dry seasons on the aquatic bacterial community structure of the Three Gorges Reservoir
This study investigated effects of wet and dry seasons on the bacterial community structure of the Three Gorges Reservoir by using denaturing gradient gel electrophoresis analysis of the PCR-amplified bacteria...
-
Article
Prokaryotic expression and functional analysis of the Mb1514 gene in Mycobacterium bovis
The ability of mycobacteria to grow and invade target tissues is the key component in the process of Mycobacterium bovis infection. Therefore, analysis of the proteins responsible for cell invasion will assist cl...
-
Article
Pluripotent-related gene expression analyses in single porcine recloned embryo
The developmental ability among embryos produced by three different techniques were examined: there were no significant differences in the developmental rate in porcine embryos produced by in vitro fertilizati...
-
Article
Genome-wide identification and analysis of basic helix-loop-helix domains in dog, Canis lupus familiaris
The basic helix-loop-helix (bHLH) domain is a highly conserved amino acid motif that defines a group of DNA-binding transcription factors. bHLH proteins play essential regulatory roles in a variety of biologic...
-
Article
Extending the linker region increases the activity of the Bacillus subtilis cellulase CelI15
To investigate the effect of the linker region (LR) on the enzymatic activity, stability, and flexibility of Bacillus subtilis cellulase CelI15, six mutants were constructed that contained increasing numbers of t...
-
Article
Artificial induction of genetic competence in Bacillus amyloliquefaciens isolates
To induce natural genetic competence in Bacillus amyloliquefaciens isolates through overexpression of the master regulator, ComK, from B. subtilis (ComK Bsu ).
-
Article
Cell-penetrating peptides induce apoptosis and necrosis through specific mechanism and cause impairment of Na+–K+-ATPase and mitochondria
Cell-penetrating peptides (CPPs) are widely used in the development of various drug delivery systems because of their ability of penetrating plasma membrane. However, the safety of their application remains la...
-
Article
Development and application of a T7 RNA polymerase-dependent expression system for antibiotic production improvement in Streptomyces
To develop a reliable and easy to use expression system for antibiotic production improvement of Streptomyces.
-
Article
Open AccessHighly efficient base editing in human tripronuclear zygotes