24 Result(s)

Article

Functional genetic variants of GEN1 predict overall survival of Chinese epithelial ovarian cancer patients

Inherited variations in DNA double-strand break (DSB) repair pathway are known to influence ovarian cancer occurrence, progression and treatment response. Despite its significance, survival-associated genetic ...

Haoran Li, Jiao Wu, Qing Xu, Yangyang Pang, Yanzi Gu… in Journal of Translational Medicine (2024)

Article

Retraction Note: LncRNA PCAT6 regulates the progression of pituitary adenomas by regulating the miR-139-3p/BRD4 axis

Peng Zhao, Jianhua Cheng, Bin Li, Ding Nie, Hongyun Wang… in Cancer Cell International (2024)

Article

Preface for special issue on nonlinear dynamics modeling and control for brain science and brain-like intelligence

Fang Han, Qingyun Wang, Jianzhong Su in Cognitive Neurodynamics (2023)

Article

BNIP3 as a potential biomarker for the identification of prognosis and diagnosis in solid tumours

Traditional radiotherapy and chemotherapy have been intensively studied for their role in the treatment of tumours. However, these therapies often cause side effects for patients, which calls for the developme...

Qin Yu, Wenhao Fu, Yutang Fu, Wen**g Ye, Huiqiong Yan, Zecheng Yu… in Molecular Cancer (2023)

Article

Strong immune responses and protection of PcrV and OprF-I mRNA vaccine candidates against Pseudomonas aeruginosa

Pseudomonas aeruginosa (PA) is a leading cause of hospital-acquired and ventilator-associated pneumonia. The multidrug-resistance (MDR) rate of PA is increasing making the management of PA a global challenge. Mes...

**ngyun Wang, Cong Liu, Nino Rcheulishvili, Dimitri Papukashvili… in npj Vaccines (2023)

Article

Risk assessment for colorectal cancer via polygenic risk score and lifestyle exposure: a large-scale association study of East Asian and European populations

The genetic architectures of colorectal cancer are distinct across different populations. To date, the majority of polygenic risk scores (PRSs) are derived from European (EUR) populations, which limits their a...

Junyi **n, Mulong Du, Dongying Gu, Kewei Jiang, Mengyun Wang… in Genome Medicine (2023)

Article

Dimethylarginine dimethylaminohydrolase 1 protects PM_2.5 exposure-induced lung injury in mice by repressing inflammation and oxidative stress

Airborne fine particulate matter with aerodynamic diameter ≤ 2.5 μm (PM_2.5) pollution is associated with the prevalence of respiratory diseases, including asthma, bronchitis and chronic obstructive pulmonary dise...

Junling Gao, Tong Lei, Hongyun Wang, Kai Luo, Yuanli Wang… in Particle and Fibre Toxicology (2022)

Article

Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells

Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of pancreas (UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had poorly described histopathological and clinical f...

**nbo Wang, Jiaying Miao, Sizhen Wang, Rongxi Shen, Shuo Zhang… in Molecular Cancer (2022)

Article

MiR-106b-5p regulates esophageal squamous cell carcinoma progression by binding to HPGD

Several studies have documented the key role of microRNAs (miRNAs) in esophageal squamous cell carcinoma (ESCC). Although the expression of the 15-hydroxyprostaglandin dehydrogenase (HPGD) gene and miR-106b-5p ar...

Fan Yang, Zhanwen Sun, Dengyun Wang, Tian Du in BMC Cancer (2022)

Article

Targets identified from exercised heart: killing multiple birds with one stone

Cardiovascular diseases (CVDs) are a major cause of mortality worldwide, which are mainly driven by factors such as aging, sedentary lifestyle, and excess alcohol use. Exercise targets several molecules and pr...

Hongyun Wang, Yuling **e, Longfei Guan, Kenneth Elkin… in npj Regenerative Medicine (2021)

Article

RETRACTED ARTICLE: LncRNA PCAT6 regulates the progression of pituitary adenomas by regulating the miR-139-3p/BRD4 axis

Dysregulated lncRNA PCAT6 was discovered in many cancers excluding pituitary adenomas (PA). Therefore, we explored the role of PCAT6 in PA in this research.

Peng Zhao, Jianhua Cheng, Bin Li, Ding Nie, Hongyun Wang… in Cancer Cell International (2021)

Article

Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series

We aimed to describe the features of 220 nonemergency (mild or common type) COVID-19 patients from a shelter hospital, as well as evaluate the efficiency of antiviral drug, Arbidol in their disease progressions.

Wei Gao, Si Chen, Kun Wang, Rongzhang Chen, Qian Guo, **g**g Lu… in Virology Journal (2020)

Article

Plasma expression of miRNA-21, − 214, −34a, and -200a in patients with persistent HPV infection and cervical lesions

To examine differences in the plasma levels of miRNA-21, − 214, −34a, and -200a in patients with persistent high-risk human papillomavirus (hr-HPV) infection or with cervical lesions of different grades.

Hongyun Wang, Dandan Zhang, Qing Chen, Ying Hong in BMC Cancer (2019)

Article

CCNB1 affects cavernous sinus invasion in pituitary adenomas through the epithelial–mesenchymal transition

To investigate the relationship between cyclin B1 (CCNB1) gene expression and cavernous sinus invasion in pituitary adenomas.

Bin Li, Jianhua Cheng, Hongyun Wang, Sida Zhao… in Journal of Translational Medicine (2019)

Article

Light-emitting diode therapy protects against ventricular arrhythmias by neuro-immune modulation in myocardial ischemia and reperfusion rat model

Sympathetic overactivation and inflammation are two major mediators to post-myocardial ischemia-reperfusion (I/R)-induced ventricular arrhythmia (VA). The vicious cycle between microglia and sympathetic activa...

Songyun Wang, Lin Wu, Xuemeng Li, Binxun Li, Yi Zhai… in Journal of Neuroinflammation (2019)

Article

Distribution of human papilloma virus genotype prevalence in invasive cervical carcinomas and precancerous lesions in the Yangtze River Delta area, China

This study aimed to provide more information for cancer prevention strategies by determining the distribution of human papilloma virus (HPV) genotype prevalence in invasive cervical carcinoma (ICC) and precanc...

Hongyun WANG, **aodong CHENG, **g YE, **uyun XU, Ying HONG, Long SUI… in BMC Cancer (2018)

Article

Six-helix bundle completion in the distal C-terminal heptad repeat region of gp41 is required for efficient human immunodeficiency virus type 1 infection

The native pre-fusion structure of gp120/gp41 complex of human immunodeficiency virus type 1 was recently revealed. In the model, the helices of gp41 (α6, α7, α8, and α9) form a four-helix collar underneath trime...

Dehua Liu, Hongyun Wang, Mizuki Yamamoto, Ji** Song, Rui Zhang… in Retrovirology (2018)

Article

UCP2 and UCP3 variants and gene-environment interaction associated with prediabetes and T2DM in a rural population: a case control study in China

There are disparities for the association between uncoupling proteins (UCP) and type 2 diabetes (T2DM). The study was to examine the associations of genetic variants of UCP2 and UCP3 with prediabetes and T2DM ...

Meifang Su, **aoying Chen, Yue Chen, Congyun Wang, Songtao Li… in BMC Medical Genetics (2018)

Article

Erratum to: A Colorimetric and Fluorescent Probe Based on Michael Acceptor Type Diketopyrrolopyrrole for Cyanide Detection

Lingyun Wang, Shaochun Zhuo, Derong Cao in Journal of Fluorescence (2017)

Article

Genetic variants of DNA repair genes predict the survival of patients with esophageal squamous cell cancer receiving platinum-based adjuvant chemotherapy

Adjuvant chemotherapy in patients with resected esophageal squamous cell cancer (ESCC) remains controversial for its uncertain role in improving overall survival (OS). Nucleotide excision repair (NER) removes ...

Fei Zhou, Meiling Zhu, Mengyun Wang, Lixin Qiu… in Journal of Translational Medicine (2016)