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13-Oxyingenol dodecanoate, a cytotoxic ingenol derivative, induces mitochondrial apoptosis and caspase-dependent Akt decrease in K562 cells

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  1. Article

    Open Access

    Retraction Note: LncRNA PCAT6 regulates the progression of pituitary adenomas by regulating the miR-139-3p/BRD4 axis

    Peng Zhao, Jianhua Cheng, Bin Li, Ding Nie, Hongyun Wang in Cancer Cell International (2024)

  2. Article

    Open Access

    BNIP3 as a potential biomarker for the identification of prognosis and diagnosis in solid tumours

    Traditional radiotherapy and chemotherapy have been intensively studied for their role in the treatment of tumours. However, these therapies often cause side effects for patients, which calls for the developme...

    Qin Yu, Wenhao Fu, Yutang Fu, Wen**g Ye, Huiqiong Yan, Zecheng Yu in Molecular Cancer (2023)

  3. Article

    Open Access

    Risk assessment for colorectal cancer via polygenic risk score and lifestyle exposure: a large-scale association study of East Asian and European populations

    The genetic architectures of colorectal cancer are distinct across different populations. To date, the majority of polygenic risk scores (PRSs) are derived from European (EUR) populations, which limits their a...

    Junyi **n, Mulong Du, Dongying Gu, Kewei Jiang, Mengyun Wang in Genome Medicine (2023)

  4. Article

    Open Access

    Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells

    Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of pancreas (UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had poorly described histopathological and clinical f...

    **nbo Wang, Jiaying Miao, Sizhen Wang, Rongxi Shen, Shuo Zhang in Molecular Cancer (2022)

  5. Article

    Open Access

    MiR-106b-5p regulates esophageal squamous cell carcinoma progression by binding to HPGD

    Several studies have documented the key role of microRNAs (miRNAs) in esophageal squamous cell carcinoma (ESCC). Although the expression of the 15-hydroxyprostaglandin dehydrogenase (HPGD) gene and miR-106b-5p ar...

    Fan Yang, Zhanwen Sun, Dengyun Wang, Tian Du in BMC Cancer (2022)

  6. Article

    Open Access

    RETRACTED ARTICLE: LncRNA PCAT6 regulates the progression of pituitary adenomas by regulating the miR-139-3p/BRD4 axis

    Dysregulated lncRNA PCAT6 was discovered in many cancers excluding pituitary adenomas (PA). Therefore, we explored the role of PCAT6 in PA in this research.

    Peng Zhao, Jianhua Cheng, Bin Li, Ding Nie, Hongyun Wang in Cancer Cell International (2021)

  7. Article

    Open Access

    Plasma expression of miRNA-21, − 214, −34a, and -200a in patients with persistent HPV infection and cervical lesions

    To examine differences in the plasma levels of miRNA-21, − 214, −34a, and -200a in patients with persistent high-risk human papillomavirus (hr-HPV) infection or with cervical lesions of different grades.

    Hongyun Wang, Dandan Zhang, Qing Chen, Ying Hong in BMC Cancer (2019)

  8. Article

    Open Access

    Distribution of human papilloma virus genotype prevalence in invasive cervical carcinomas and precancerous lesions in the Yangtze River Delta area, China

    This study aimed to provide more information for cancer prevention strategies by determining the distribution of human papilloma virus (HPV) genotype prevalence in invasive cervical carcinoma (ICC) and precanc...

    Hongyun WANG, **aodong CHENG, **g YE, **uyun XU, Ying HONG, Long SUI in BMC Cancer (2018)

  9. Article

    Open Access

    Six-helix bundle completion in the distal C-terminal heptad repeat region of gp41 is required for efficient human immunodeficiency virus type 1 infection

    The native pre-fusion structure of gp120/gp41 complex of human immunodeficiency virus type 1 was recently revealed. In the model, the helices of gp41 (α6, α7, α8, and α9) form a four-helix collar underneath trime...

    Dehua Liu, Hongyun Wang, Mizuki Yamamoto, Ji** Song, Rui Zhang in Retrovirology (2018)

  10. Article

    Open Access

    Suppression of the epithelial-mesenchymal transition by SHARP1 is linked to the NOTCH1 signaling pathway in metastasis of endometrial cancer

    Mechanisms governing the metastasis of endometrial cancer (EC) are poorly defined. Recent data support a role for Enhancer-of-split and hairy-related protein 1 (SHARP1), a basic helix-loop-helix transcription ...

    Yun Liao, **aoying He, Haifeng Qiu, Qi Che, Fangyuan Wang, Wen Lu, Zheng Chen in BMC Cancer (2014)

  11. Article

    Open Access

    FOXA1 promotes tumor cell proliferation through AR involving the Notch pathway in endometrial cancer

    Increasing evidence suggests that forkhead box A1 (FOXA1) is frequently dysregulated in many types of human cancers. However, the exact function and mechanism of FOXA1 in human endometrial cancer (EC) remains ...

    Meiting Qiu, Wei Bao, **gyun Wang, Tingting Yang, **aoying He, Yun Liao in BMC Cancer (2014)