2,316 Result(s)
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Article
**fa Guan
Life Sciences
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Article
Isolation, identification and transcriptome analysis of triadimefon-degrading strain Enterobacter hormaechei TY18
Triadimefon, a type of triazole systemic fungicide, has been extensively used to control various fungal diseases. However, triadimefon could lead to severe environmental pollution, and even threatens human hea...
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The effect of bioC gene on ultraviolet radiation and oxidative resistance of Bacillus thuringiensis (Bacillales: Bacillaceae)
Bacillus thuringiensis (Bacillales: Bacillaceae) (Bt) has played a significant role in pest control, which is the most intensively studied, rapidly developed, and widely used insecticidal microorganism in recent ...
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Rutin Ameliorates Toxoplasma gondii-Induced Brain Tissue Damage via Inhibiting P2X7R/NLRP3 Pro-Inflammatory and Enhancing PI3K/AKT/Nrf2/HO-1 Antioxidant Signaling Pathway
Bain damage caused by Toxoplasma gondii (T. gondii) is associated with increased inflammatory response and oxidative stress. Rutin, a natural product extracted from tobacco leaves and tomatoes, has excellent anti...
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Comprehensive genome-wide identification of Snf2 gene family and their expression profile under salt stress in six Brassica species of U’s triangle model
We comprehensively identified and analyzed the Snf2 gene family. Some Snf2 genes were involved in responding to salt stress based on the RNA-seq and qRT-PCR analysis.
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Niclosamide modulates phenotypic switch and inflammatory responses in human pulmonary arterial smooth muscle cells
Excessive proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) represent key steps of pulmonary vascular remodeling, leading to the development of pulmonary arterial hypertension (PAH...
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Open AccessTracking the hologenome dynamics in aquatic invertebrates by the holo-2bRAD approach
The “hologenome” concept is an increasingly popular way of thinking about microbiome-host for marine organisms. However, it is challenging to track hologenome dynamics because of the large amount of material, ...
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Sod Culture Treatments Positively Affect Soil Fungal Diversity, Soil Enzyme Activities, and Nutrient Uptake in Navel Orange Orchards
Gannan navel oranges (Citrus sinensis Osb. var. brasliliensis Tanaka) are mainly cultivated in mountain orchards. However, inappropriate long-term management practices such as clean cultivation and excessive use ...
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Open AccessDelivery of miR-15b-5p via magnetic nanoparticle-enhanced bone marrow mesenchymal stem cell-derived extracellular vesicles mitigates diabetic osteoporosis by targeting GFAP
Diabetic osteoporosis (DO) presents significant clinical challenges. This study aimed to investigate the potential of magnetic nanoparticle-enhanced extracellular vesicles (GMNPE-EVs) derived from bone marrow mes...
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Biocontrol potential of plant growth-promoting rhizobacteria against plant disease and insect pest
Biological control is a promising approach to enhance pathogen and pest control to ensure high productivity in cash crop production. Therefore, PGPR biofertilizers are very suitable for application in the cult...
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Genome editing of RICE FLOWERING LOCUS T 1 promoter delayed flowering in rice
The heading date of rice is a crucial agronomic traits affecting regional adaptation and grain productivity. Manipulating the vegetative growth period or delaying flowering can increase the yield and quality. ...
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Screening of Strain from Reconstituted Sheet Tobacco Making High-Yield Enzyme and Aroma
Reconstituted sheet tobacco (RST) is critical to the quality of cigarette. The purpose of this study was to extract and cultivate bacteria from tobacco leaf stalks, scraps, and concentrate from RST production ...
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Open AccessA broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug
SARS-CoV-2 infection is initiated by Spike glycoprotein binding to the human angiotensin-converting enzyme 2 (ACE2) receptor via its receptor binding domain. Blocking this interaction has been proven to be an ...
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Root Disturbance Effects of Four Halophytes on Soil Physiochemical Charismatics in Intertidal Ecotone of the Yellow River Estuary
Four representative halophytes, Tamarix chinensis (Tc), Phragmites australis (Pa), Suaeda salsa (Ss), and Spartina alterniflora (Sa), in the Yellow River Estuary wetland were selected to clarify the root disturba...
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Open AccessMetataxonomic and metabolomic profiling revealed Pinus koraiensis cone essential oil reduced methane emission through affecting ruminal microbial interactions and host-microbial metabolism
Pinus koraiensis cone essential oil (PEO) contains functional compounds such as monoterpene hydrocarbons, and the administration of PEO reduced methane (CH4) emissions during growing phase of goats. However, the ...
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Open AccessTesting the amount of nicotinamide mononucleotide and urolithin A as compared to the label claim
Healthy Longevity Medicine aims to optimize health by targeting aging processes across the lifespan. Addressing accelerated aging involves adaptation of lifestyle and the use of geroprotective drugs and supple...
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Open AccessLIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism
LIMA1 is a LIM domain and Actin binding 1 protein that acts as a skeleton protein to promote cholesterol absorption, which makes it an ideal target for interfering with lipid metabolism. However, the detailed ...
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Open AccessDietary Supplementation of Compound Probiotics Improves Intestinal Health by Modulated Microbiota and Its SCFA Products as Alternatives to In-Feed Antibiotics
Enterococcus faecium, Bifidobacterium, and Pediococcus acidilactici, as intestinal probiotics, have been proved to play a positive role in treating intestinal diseases, promoting growth and immune regulation in p...
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Open AccessDeciphering spatial domains from spatial multi-omics with SpatialGlue
Advances in spatial omics technologies now allow multiple types of data to be acquired from the same tissue slice. To realize the full potential of such data, we need spatially informed methods for data integr...
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Open AccessGenome-wide identification of ATG genes and their expression profiles under biotic and abiotic stresses in Fenneropenaeus chinensis
Autophagy is a conserved catabolic process in eukaryotes that contributes to cell survival in response to multiple stresses and is important for organism fitness. Extensive research has shown that autophagy pl...
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Coordinated action of a gut–liver pathway drives alcohol detoxification and consumption
Alcohol use disorder (AUD) affects millions of people worldwide, causing extensive morbidity and mortality with limited pharmacological treatments. The liver is considered as the principal site for the detoxif...
