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Metabolic Diseases
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Outpatient reception via collaboration between nurses and a large language model: a randomized controlled trial
Reception is an essential process for patients seeking medical care and a critical component influencing the healthcare experience. However, current communication systems rely mainly on human efforts, which ar...
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Author Correction: A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma
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Open AccessConsumer wearable devices for evaluation of heart rate control using digoxin versus beta-blockers: the RATE-AF randomized trial
Consumer-grade wearable technology has the potential to support clinical research and patient management. Here, we report results from the RATE-AF trial wearables study, which was designed to compare heart rat...
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Open AccessClinical effects of teriparatide, abaloparatide, and romosozumab in postmenopausal osteoporosis
In the management of osteoporosis, anti-resorptive agents serve as a primary therapeutic approach. However, in cases where individuals exhibit an increased susceptibility to fractures, such as those characteri...
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Inositols and female reproduction disorders: a consensus statement from the working group of the Club of the Italian Society of Endocrinology (SIE)—Women’s Endocrinology
To provide the latest scientific knowledge on the efficacy of inositols for improving reproductive disorders in women with and without polycystic ovary syndrome (PCOS) and to reach a consensus on their potenti...
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Open AccessPredictors of response to Radioactive Iodine Therapy in Intermediate and high risk patients with papillary thyroid carcinoma
Radioactive iodine (RAI) therapy is the standard treatment approach after total thyroidectomy in patients with papillary thyroid carcinoma (PTC). We aimed to identify predictive factors of response to the trea...
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Open AccessThe association between waist-to-hip ratio (WHR) with diabetes in the PERSIAN Guilan cohort study population
Waist circumference (WC), or waist-to-hip ratio (WHR), potentially offers a more accurate reflection of intra-abdominal fat accumulation and could serve as a superior predictor of type 2 diabetes mellitus (T2D...
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Open AccessEffect of recurrent severe insulin-induced hypoglycemia on the cognitive function and brain oxidative status in the rats
Episodes of recurrent or severe hypoglycemia can occur in patients with diabetes mellitus, insulinoma, neonatal hypoglycemia, and medication errors. However, little is known about the short-term and long-term ...
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Acute effects of dynamic stretching exercises on vertical jump performance and flexibility
This study was conducted to examine the acute effects of dynamic stretching exercises (DSE) on vertical jump height (VJH), muscle strength (MS), and flexibility in athletes and sedentary individuals.
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A comprehensive cancer center in the cloud powered by AI can reduce health disparities
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Precision health could mitigate clinical biases that impact care
Shivani Misra describes how meeting a misdiagnosed patient early in her career led her to study precision diabetes in underrepresented groups.
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Predictors of parent self-monitoring patterns in a family-based behavioral weight loss treatment program
Self-monitoring dietary intake is a critical component of family-based intensive health behavior and lifestyle treatment for pediatric obesity, but adherence rates are often low. This study identifies predicto...
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Open AccessComparison of clinical characteristics and treatment outcomes between initially diagnosed type 1 and type 2 diabetes mellitus patients presenting with diabetic ketoacidosis
Patients with type 1 diabetes (T1DM) and type 2 diabetes (T2DM) can present with diabetic ketoacidosis (DKA) as the first manifestation. Differentiating types of newly diagnosed diabetes could provide appropri...
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Open AccessEarly changes of microRNAs in blood one month after bariatric surgery
Changes in microRNAs (miRNAs) are relevant to bariatric surgery and its comorbidities. The characteristics of changes in miRNAs of the early postoperative period following both bariatric procedures, sleeve gas...
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Open AccessAssessment of glycemic susceptibility across multiple urological and reproductive disorders
To test the glycemic susceptibility in three urological cancers and eight urological/reproductive diseases using the Mendelian randomization (MR) method.
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A life-course multisectoral approach to precision health in LMICs
Precision health in low- and middle-income countries should focus on disease prevention and implementation in order to be cost-effective and impactful.
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Thyroid complications after hemopoietic stem cell transplantation in children and adolescents
To evaluate the prevalence of thyroid dysfunction and its association with possible contributing factors related to diagnosis and treatment in children who received hematopoietic stem cell transplantation (HSC...
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Open AccessImaging-based body fat distribution and diabetic retinopathy in general US population with diabetes: an NHANES analysis (2003–2006 and 2011–2018)
Limited studies have investigated the correlation between fat distribution and the risk of diabetic retinopathy (DR) in the general population with diabetes. The relationship between obesity and DR remains inc...
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Effects of exercise mimetics as putative therapeutics on brain health, aging, and neurodegenerative diseases
There is growing evidence that an active lifestyle can benefit brain health, delay the onset of neurodegenerative diseases and aging, and improve mood and cognitive function. Results seem to show that exercise...
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Open AccessCharacterization of obesity-related diseases and inflammation using single cell immunophenoty** in two different diet-induced obesity models
Obesity is a growing problem worldwide and a major risk factor for many chronic diseases. The accumulation of adipose tissue leads to the release of significant amounts of pro-inflammatory cytokines and adipok...
