52 Result(s)
within
English
Biomedicine
**ao-xiang **e
Article
-
Article
Protective effects of bendazac lysine on early experimental diabetic nephropathy in rats
To investigate the preventive and protective effects of bendazac lysine (BDL) on experimental early diabetic nephropathy (DN) rats.
-
Article
Effects of astragaloside IV on pathogenesis of metabolic syndrome in vitro
To investigate the diverse pharmacological actions of astragaloside IV from the perspective of metabolic syndrome, and to investigate the effect of the drug on the pathogenesis of metabolic syndrome.
-
Article
Anti-inflammatory effects of a novel peptide designed to bind with NF-κB p50 subunit
To explore the anti-inflammatory effects of a novel peptide designed to bind with the NF-κB p50 subunit.
-
Article
Open AccessDetection of lymphangiogenesis in non-small cell lung cancer and its prognostic value
Our aim was to detect lymphatic endothelial marker podoplanin, lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) and vascular endothelial growth factor receptor-3 (VEGFR)-3 and study the prognostic r...
-
Article
Point-of-care test of heart-type fatty acid-binding protein for the diagnosis of early acute myocardial infarction
To investigate the efficacies of point-of-care test of heart-type fatty-acid binding protein (H-FABP) and its combinations with the conventional biomarkers in the diagnosis of early acute myocardial infarction...
-
Article
Open AccessHeterologous SH3-p85β inhibits influenza A virus replication
Phosphatidylinositol 3-kinase (PI3K)/Akt signalling pathway can support the replication of influenza A virus through binding of viral NS1 protein to the Src homology 3 (SH3) domain of p85β regulatory subunit o...
-
Article
Open AccessRadiosensitization and growth inhibition of cancer cells mediated by an scFv antibody gene against DNA-PKcs in vitro and in vivo
Overexpression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is commonly occurred in cancers and causes radioresistance and poor prognosis. In present study, the single-chain variable antibody f...
-
Article
Open AccessMicroarray-based analysis of microRNA expression in breast cancer stem cells
This study aimed to determine the miRNA profile in breast cancer stem cells (BCSCs) and to explore the functions of characteristic BCSC miRNAs.
-
Article
N-benzyl-5-phenyl-1H-pyrazole-3-carboxamide promotes vascular endothelial cell angiogenesis and migration in the absence of serum and FGF-2
To investigate the effect of N-benzyl-5-phenyl-1H-pyrazole-3-carboxamide (BPC) on angiogenesis in human umbilical vein endothelial cells (HUVECs).
-
Article
Open AccessArtesunate potentiates antibiotics by inactivating heme-harbouring bacterial nitric oxide synthase and catalase
A current challenge of co** with bacterial infection is that bacterial pathogens are becoming less susceptible to or more tolerant of commonly used antibiotics. It is urgent to work out a practical solution ...
-
Article
Open AccessMicroRNA-196a promotes non-small cell lung cancer cell proliferation and invasion through targeting HOXA5
MicroRNAs (miRNAs) are short, non-coding RNAs (~22 nt) that play important roles in the pathogenesis of human diseases by negatively regulating gene expression. Although miR-196a has been implicated in several...
-
Article
Effects of nicotine stimulation on spikes, theta frequency oscillations, and spike-theta oscillation relationship in rat medial septum diagonal band Broca slices
Spiking activities and neuronal network oscillations in the theta frequency range have been found in many cortical areas during information processing. The aim of this study is to determine whether nicotinic a...
-
Article
Novel ferrocenyl derivatives exert anti-cancer effect in human lung cancer cells in vitro via inducing G1-phase arrest and senescence
To investigate the effects of 7 novel 1-ferrocenyl-2-(5-phenyl-1H-1,2,4-triazol-3-ylthio) ethanone derivatives on human lung cancer cells in vitro and to determine the mechanisms of action.
-
Article
Open AccessThe long non-coding RNA HOTAIR indicates a poor prognosis and promotes metastasis in non-small cell lung cancer
The identification of cancer-associated long non-coding RNAs and the investigation of their molecular and biological functions are important for understanding the molecular biology and progression of cancer. H...
-
Article
Open AccessAntitumor efficacy of a recombinant adenovirus encoding endostatin combined with an E1B55KD-deficient adenovirus in gastric cancer cells
Gene therapy using a recombinant adenovirus (Ad) encoding secretory human endostatin (Ad-Endo) has been demonstrated to be a promising antiangiogenesis and antitumor strategy of in animal models and clinical t...
-
Article
Co-activation of nAChR and mGluR induces γ oscillation in rat medial septum diagonal band of Broca slices
To examine whether co-activation of nAChR and mGluR1 induced γ oscillation (20–60 Hz) in rat medial septum diagonal band of Broca (MSDB) slices.
-
Article
Open AccessDownregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition
Recent evidence indicates that long noncoding RNAs (lncRNAs) play a critical role in the regulation of cellular processes, such as differentiation, proliferation and metastasis. These lncRNAs are found to be d...
-
Article
Open AccessLnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer
Accumulating evidence indicates that the long non-coding RNA HOTAIR plays a critical role in cancer progression and metastasis. However, the overall biological role and clinical significance of HOTAIR in gastr...
-
Article
Association between serum vitamin D and severity of liver fibrosis in chronic hepatitis C patients: a systematic meta-analysis
To conduct a systematic review of group studies assessing the association of serum vitamin D status with the severity of liver fibrosis in chronic hepatitis C patients using meta-analysis. The relevant researc...
-
Article
Open AccessToxic epidermal necrolysis related to AP (pemetrexed plus cisplatin) and gefitinib combination therapy in a patient with metastatic non-small cell lung cancer
Toxic epidermal necrolysis (TEN) is a rare acute life-threatening mucocutaneous disorder that is mostly drug-related (80%–95%). It is clinically characterized as a widespread sloughing of the skin and mucosa. ...
