47 Result(s)
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**anghua Huang
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Open AccessRelationships between nine neuropsychiatric disorders and cervical cancer: insights from genetics, causality and shared gene expression patterns
Neuropsychiatric disorders and cervical cancer exert substantial influences on women’s health. Furthermore, neuropsychiatric disorders frequently manifest as common symptoms in cancer patients, potentially inc...
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Desktop-Stereolithography 3D Printing of a Decellularized Extracellular Matrix/Mesenchymal Stem Cell Exosome Bioink for Vaginal Reconstruction
3D-printing is widely used in regenerative medicine and is expected to achieve vaginal morphological restoration and true functional reconstruction. Mesenchymal stem cells-derived exosomes (MSCs-Exos) were app...
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Open AccessChromosomal-level genome assembly and annotation of the tropical sea cucumber Holothuria scabra
Holothuria scabra, a commercially valuable yet ecologically vulnerable tropical holothuroid, has experienced a severe decline in its wild populations, especially in China. Genomic resources are crucial for the de...
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Open AccessClonal expansion of shared T cell receptors reveals the existence of immune commonality among different lesions of synchronous multiple primary lung cancer
The increase in the detection rate of synchronous multiple primary lung cancer (MPLC) has posed remarkable clinical challenges due to the limited understanding of its pathogenesis and molecular features. Here,...
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Acute kidney injury during autologous stem cell transplantation in light chain amyloidosis with kidney involvement and their impact on prognosis
Acute kidney injury (AKI) is a complication related to important organ dysfunction during autologous stem cell transplantation (ASCT) in light chain (AL) amyloidosis. This study aims to validate the risk facto...
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Open AccessRapid evolution of an adaptive multicellular morphology of Candida auris during systemic infection
Candida auris has become a serious threat to public health. The mechanisms of how this fungal pathogen adapts to the mammalian host are poorly understood. Here we report the rapid evolution of an adaptive C. auri...
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Risk factors, treatments and outcomes of patients with light chain amyloidosis who relapse after autologous stem cell transplantation
Relapse after ASCT is an important factor affecting the long-term prognosis of patients with AL amyloidosis. However, the risk factors of relapse are unknown and there are limited studies on treatment outcomes...
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Open AccessMicroglia regulate sleep through calcium-dependent modulation of norepinephrine transmission
Sleep interacts reciprocally with immune system activity, but its specific relationship with microglia—the resident immune cells in the brain—remains poorly understood. Here, we show in mice that microglia can...
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Alternative Biological Material for Tissue Engineering of the Vagina: Porcine-Derived Acellular Vaginal Matrix
Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a severe congenital disorder characterized by vaginal hypoplasia caused by dysplasia of the Müllerian duct. Patients with MRKH syndrome often require nonsurgic...
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Open AccessObstetric blood transfusion in placenta previa patients with prenatal anemia: a retrospective study
The appropriate use of obstetric blood transfusion is crucial for patients with placenta previa and prenatal anemia. This retrospective study aims to explore the correlation between prenatal anemia and blood t...
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Open AccessExpression profile analysis of LncRNAs and mRNAs in pre-receptive endometrium of women with polycystic ovary syndrome undergoing in vitro fertilization-embryo transfer
To compare the expression levels of long non-coding RNA (lncRNA) and messenger RNA (mRNA) in pre-receptive endometrium between patients with Polycystic Ovary Syndrome (PCOS)and normal ovulation undergoing in v...
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Settlement Analysis of Mud-Water Shield Passing Full-Face Water-Rich Sand and Cobble Stratum Under Luo River
The shield construction of Line 2 of Luoyang Metro is designed to under-cross Luo River, the soils around the shield tunnels are composed of cobble, the permeability coefficient is about 140.0 m/d, the grain s...
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Atmospheric humidity regulates same-sex mating in Candida albicans through the trehalose and osmotic signaling pathways
Sexual reproduction is prevalent in eukaryotic organisms and plays a critical role in the evolution of new traits and in the generation of genetic diversity. Environmental factors often have a direct impact on...
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Open AccessEffect of placenta location detected by ultrasound on the severity of placenta accreta spectrum in patients with placenta previa and placenta accreta spectrum
To evaluate the effect of placental location on the severity of placenta accreta spectrum (PAS).
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Fixed-time distributed robust optimization for economic dispatch with event-triggered intermittent control
This paper proposes a fixed-time distributed robust optimization approach for solving economic dispatch problems. Based on an integral sliding mode control scheme, the proposed multi-agent system converges to ...
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Open AccessGlucose depletion enables Candida albicans mating independently of the epigenetic white-opaque switch
The human fungal pathogen Candida albicans can switch stochastically and heritably between a “white” phase and an “opaque” phase. Opaque cells are the mating-competent form of the species, whereas white cells are...
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De novo genome assembly and annotation of Holothuria scabra (Jaeger, 1833) from nanopore sequencing reads
Holothuria scabra is a costly gourmet and traditional Chinese tonic medicine. However, the lack of high-quality genome information hinders the genetic, phylogenetic, and bioactivator researches.
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Open AccessClinicopathologic characteristics and prognostic analysis of monoclonal gammopathy of renal significance (MGRS) in patients with IgM monoclonal gammopathy: a case series
Monoclonal gammopathy has emerged as an important cause of renal injury. Since the clinicopathologic features related to monotypic monoclonal gammopathy of renal significance with IgM monoclonal gammopathy (Ig...
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Examining the Association between Family Environment and Adolescent Delinquent Behaviours in China
We examined the association between perceived family environment and delinquent behaviours among Chinese adolescents. A sample of 176 middle school students (M = 13.7, SD = 0.86) completed the Chinese version of ...
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Open AccessDrug-free in vitro activation combined with 3D-bioprinted adipose-derived stem cells restores ovarian function of rats with premature ovarian insufficiency
Emerging drug-free in vitro activation (IVA) technique enables patients with premature ovarian insufficiency (POI) to restore ovarian function and conceive their own genetic offspring. However, various issues ...
