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Article
A novel dual-signal output strategy for POCT of CEA based on a smartphone electrochemical aptasensing platform
A smartphone-based electrochemical aptasensing platform was developed for the point-of-care testing (POCT) of carcinoembryonic antigen (CEA) based on the ferrocene (Fc) and PdPt@PCN-224 dual-signal labeled st...
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Article
Unraveling the Mechanisms of Cannabidiol’s Pharmacological Actions: A Comprehensive Research Overview
Cannabis sativa has long been used for neurological and psychological healing. Recently, cannabidiol (CBD) extracted from cannabis sativa has gained prominence in the medical field due to its non-psychotropic ...
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Article
ITGB4 Serves as an Identification and Prognosis Marker Associated with Immune Infiltration in Small Cell Lung Carcinoma
Integrin beta 4 (ITGB4) is a vital factor for numerous cancers. However, no reports regarding ITGB4 in small cell lung carcinoma (SCLC) have been found in the existing literature. This study systematically invest...
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Article
Chemical Recycling of Poly(ethylene furanoate) into Value-added Poly(ethylene-co)-isosorbide furanoate)
We present here a novel strategy for the chemical recycling of bio-based poly(ethylene furanoate)s (PEF) to value-added high-performance bio-based poly(ethylene-co-isosorbide furanoate) (PEIF) copolyesters by the...
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Article
Open AccessWhole fresh fruit intake and risk of incident diabetes in different glycemic stages: a nationwide prospective cohort investigation
Fruit intake is beneficial to several chronic diseases, but controversial in diabetes. We aimed to investigate prospectively the associations of whole fresh fruit intake with risk of incident type 2 diabetes (...
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Article
Structures of the ADGRG2–Gs complex in apo and ligand-bound forms
Adhesion G protein-coupled receptors are elusive in terms of their structural information and ligands. Here, we solved the cryogenic-electron microscopy (cryo-EM) structure of apo-ADGRG2, an essential membrane...
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Article
Open AccessBoron-lead multiple bonds in the PbB2O– and PbB3O2– clusters
Despite its electron deficiency, boron can form multiple bonds with a variety of elements. However, multiple bonds between boron and main-group metal elements are relatively rare. Here we report the observatio...
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Article
Stress-Structure Relationship of the Reversible Associating Polymer Network under Start-up Shear Flow
We adopt Langevin dynamics to explore the stress-structure relationship of telechelic reversible associating polymer gel during startup shear flow, with shear strengths varying from Wi = 12.6 to Wi = 12640. At we...
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Article
Rapid Determination of Sulfonamides in Chicken Muscle and Milk Using Efficient Graphene Oxide-Based Monolith On-Line Solid-Phase Extraction Coupled with Liquid Chromatography–Tandem Mass Spectrometry
A graphene oxide-incorporated monolithic column was fabricated and developed as an on-line solid-phase extraction sorbent coupled with LC-MS/MS for the automatic and fast determination of 16 sulfonamides in ch...
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Article
Solutions of the Klein–Gordon equation with the improved Tietz potential energy model
We present the relativistic rotation–vibrational energy equation of a diatomic molecule which moves under the improved Tietz potential energy model in higher spatial dimensions. The nonrelativistic limits of t...
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Article
A strategy of utilizing Zn(II) as metallic pivot in room temperature ionic liquid to prepare molecularly imprinted polymers for compound with intramolecular hydrogen bonds
A method of preparing molecularly imprinted polymers (MIPs) with Zn(II) as a metallic pivot was adopted to solve the problem of imprinting compound with intramolecular hydrogen bonds by forming stronger coordi...
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Article
Chemoselective synthesis of 1,2-disubstituted benzimidazoles in lactic acid without additive
Lactic acid is recognised as a biocompatible medium for the chemoselective synthesis of the 1,2-disubstituted benzimidazole scaffold via a direct one-pot cyclocondensation of o-phenylenediamine with aldehydes....
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Article
D-dimensional energies for scandium monoiodide
We solve the Schrödinger equation with the Morse potential energy model in \(D\) ...
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Article
Hydrodynamic characters of co-current operation for SO2 absorption in a laboratory packed column
A co-current operation for SO2 absorption by water was performed in a laboratory-scale packed column. The effects of L/V (liquid-gas ratio) and F (gas phase loading factor) on the SO2 absorptivity were both inves...
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Article
Chemical and structural biology of nucleic acids and protein-nucleic acid complexes for novel drug discovery
Since nucleic acids (DNA and RNA) play very important roles in cells, they are molecular targets of many clinically used drugs, such as anticancer drugs and antibiotics. Because of clinical demands for treatin...
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Article
Solvothermal Syntheses and Crystal Structures of Rare Earth Thioantimonates [Y(en)4]SbS4·0.5en and [Tm(en)4]SbS4·0.5en
Two rare earth metal thioantimonates [RE(en)4]SbS4·0.5en (RE = Y(1), Tm(2); en = ethylenediamine) were synthesized under mild solvothermal conditions. Compounds 1 and 2 are isostructural, and both crystallize in ...
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Article
Chlorofullerenes featuring triple sequentially fused pentagons
The triple sequentially fused pentagons (TSFP) motif is one of the basic subunits that could be used for constructing fullerenes, but it violates the isolated pentagon rule (IPR) and has not been found in carb...
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Article
Optimization of Effect Factors for Mycelial Growth and Exopolysaccharide Production by Schizophyllum commune
This paper is concerned with the optimization of effect factors for mycelial growth and exopolysaccharide production by Schizophyllum commune by one-factor-at-a-time and orthogonal methods. The one-factor-at-a-ti...