Skip to main content

19 Result(s)

within Life Sciences Remove this filter Biomedicine, general Remove this filter Cell Biology Remove this filter Microbiology Remove this filter **an Qi Remove this filter Article Remove this filter

and

  1. No Access

    Article

    Fatty acid metabolism-related molecular subtypes and a novel model for predicting prognosis in bladder cancer patients

    This study aims to develop fatty acid metabolism-related molecular subtypes and construct a fatty acid metabolism-related novel model for bladder cancer (BCa) by bioinformatic profiling. Genome RNA-seq express...

    Wen-Ting Su, Jia-Yin Chen, Jiang-Bo Sun, Qi Huang, Zhi-Bin Ke… in Journal of Biosciences (2024)

  2. No Access

    Article

    LncRNA-SNHG16 promotes proliferation and migration of acute myeloid leukemia cells via PTEN/PI3K/AKT axis through suppressing CELF2 protein

    The silence of lncRNA small nucleolar RNA host gene 16 (SNHG16) suppressed acute lymphoblastic leukemia (ALL) cell proliferation and migration, whereas its role in acute myeloid leukemia (AML) still lacks clarity...

    Min Shi, Ruili Yang, **g Lin, Qi Wei, Lei Chen, Weifeng Gong… in Journal of Biosciences (2021)

  3. No Access

    Article

    β-Actin facilitates etoposide-induced p53 nuclear import

    As a tumor suppressor, p53 preserves genomic integrity in eukaryotes. However, limited evidence is available for the p53 shuttling between the cytoplasm and nucleus. Previous studies have shown that β-actin po...

    Wen**g Qi, **jiao Li, **aohua Pei, Yueshuang Ke, Qingpan Bu… in Journal of Biosciences (2020)

  4. No Access

    Article

    Down-regulation of microRNA-216a confers protection against yttrium aluminium garnet laser-induced retinal injury via the GDNF-mediated GDNF/GFRα1/RET signalling pathway

    Retinal injury plays a leading role in the onset of visual impairment. Current forms of treatment are not able to ameliorate scarring, cell death and tissue and axon regeneration. Recently, microRNA-216a (miR-...

    **-Bin Hu, Shu-Hua Fu, Qi Luo, Jian-Zhong He, Yan-Fei Qiu… in Journal of Biosciences (2018)

  5. No Access

    Article

    miR-200a-3p promotes β-Amyloid-induced neuronal apoptosis through down-regulation of SIRT1 in Alzheimer’s disease

    The aberrantly expressed microRNAs (miRNAs) including miR-200a-3p have been reported in the brains of Alzheimer’s disease (AD) patients in recent researches. Nevertheless, the role of miR-200a-3p in AD has not...

    Qi-Shun Zhang, Wei Liu, Guang-**u Lu in Journal of Biosciences (2017)

  6. No Access

    Article

    Genetic diagnosis of a Chinese multiple endocrine neoplasia type 2A family through whole genome sequencing

    Approximately 98% of patients with multiple endocrine neoplasia type 2A (MEN 2A) have an identifiable RET mutation. Prophylactic or early total thyroidectomy or pheochromocytoma/parathyroid removal in patients ca...

    Zhen-Fang Du, Peng-Fei Li, Jian-Qiang Zhao, Zhi-Lie Cao, Feng Li… in Journal of Biosciences (2017)

  7. No Access

    Article

    Human cytomegalovirus-encoded miR-US4-1 promotes cell apoptosis and benefits discharge of infectious virus particles by targeting QARS

    Human cytomegalovirus (HCMV) can cause congenital diseases and opportunistic infections in immunocompromised individuals. Its functional proteins and microRNAs (miRNAs) facilitate efficie...

    Yaozhong Shao, Ying Qi, Yu**g Huang, Zhongyang Liu, Yan** Ma… in Journal of Biosciences (2016)

  8. No Access

    Article

    Host protein Snapin interacts with human cytomegalovirus pUL130 and affects viral DNA replication

    The interplay between the host and Human cytomegalovirus (HCMV) plays a pivotal role in the outcome of an infection. HCMV growth in endothelial and epithelial cells requires expression of viral proteins UL128, UL...

    Guili Wang, Gaowei Ren, **n Cui, Zhitao Lu, Yanpin Ma, Ying Qi… in Journal of Biosciences (2016)

  9. No Access

    Article

    The rare intracellular RET mutation p.S891A in a Chinese Han family with familial medullary thyroid carcinoma

    We report intracellular RET mutation in a Han Chinese pedigree with familial medullary thyroid carcinoma (FMTC). Direct sequencing of RET proto-oncogene identified a missense c.2671T>G (p.S891A) mutation in 6 of ...

    **ao-** Qi, Rong-**n Zhang, **-Lin Cao, Zhen-Guang Chen… in Journal of Biosciences (2014)

  10. No Access

    Article

    Down-regulation of human cytomegalovirus UL138, a novel latency-associated determinant, by hcmv-miR-UL36

    MicroRNAs (miRNAs) are small RNAs, 19–23 nucleotides in length, which regulate a variety of cellular processes. Human cytomegalovirus (HCMV) encodes only one intronic miRNA: human cytomegalovirus microRNA UL36...

    Yu**g Huang, Ying Qi, Yan** Ma, Rong He, Yaohua Ji… in Journal of Biosciences (2013)

  11. No Access

    Article

    Fluorescent tag is not a reliable marker for small RNA transfection in the presence of serum

    Chemically synthetic siRNA and miRNA have become powerful tools to study gene function in the past decade. Fluorescent dyes covalently attached to the 5′ or 3′ ends of synthetic small RNAs are widely used for ...

    **g Han, Qi-Wei Wang, Shi-Qiang Wang in Journal of Biosciences (2013)

  12. No Access

    Article

    Functional analyses of a flavonol synthase–like gene from Camellia nitidissima reveal its roles in flavonoid metabolism during floral pigmentation

    The flavonoids metabolic pathway plays central roles in floral coloration, in which anthocyanins and flavonols are derived from common precursors, dihydroflavonols. Flavonol synthase (FLS) catalyses dihydrofla...

    **ng-Wen Zhou, Zheng-Qi Fan, Yue Chen, Yu-Lin Zhu, Ji-Yuan Li… in Journal of Biosciences (2013)

  13. No Access

    Article

    Overlap** transcription structure of human cytomegalovirus UL140 and UL141 genes

    Transcription of human cytomegalovirus UL/b′ region has been studied extensively for some genes. In this study, transcripts of the UL140 and UL141, two of the UL/b′ genes, were identified in late RNAs of three...

    Yan** Ma, Mali Li, Bo Zheng, Ning Wang, Shuang Gao, Lin Wang… in Journal of Biosciences (2013)

  14. No Access

    Article

    Molecular cytogenetic identification of a novel dwarf wheat line with introgressed Thinopyrum ponticum chromatin

    Novel dwarfing germplasms and dwarfing genes are valuable for the wheat breeding. A novel semi-dwarf line, 31505-1, with reduced height compared with its common wheat parent, was derived from a cross between c...

    Guiling Chen, Qi Zheng, Yinguang Bao, Shubing Liu, Honggang Wang… in Journal of Biosciences (2012)

  15. No Access

    Article

    Transcription pattern of UL131A-128 mRNA in clinical strains of human cytomegalovirus

    Human cytomegalovirus (HCMV) mRNA was obtained from human embryonic lung fibroblast cells infected by HCMV clinical strains from urine samples of infants at different kinetic periods. The cDNA of UL131A-128 mRNAs...

    Zhengrong Sun, Gaowei Ren, Yan** Ma, Ning Wang, Yaohua Ji… in Journal of Biosciences (2010)

  16. No Access

    Article

    Redifferentiation of human hepatoma cells (SMMC-7721) induced by two new highly oxygenated bisabolane-type sesquiterpenes

    Bisabolane-type sesquiterpenes are a class of biologically active compounds that has antitumour, antifungal, antibacterial, antioxidant and antivenom properties. We investigated the effect of two new highly ox...

    Ruidong Miao, Juan Wei, Qi Zhang, Venkateswara Sajja, **bo Yang… in Journal of Biosciences (2008)

  17. No Access

    Article

    Human cytomegalovirus UL145 gene is highly conserved among clinical strains

    Human cytomegalovirus (HCMV), a ubiquitous human pathogen, is the leading cause of birth defects in newborns. A region (referred to as UL/b′) present in the Toledo strain of HCMV and low-passage clinical isola...

    Zhengrong Sun, Ying Lu, Qiang Ruan, Yaohua Ji, Rong He, Ying Qi… in Journal of Biosciences (2007)

  18. No Access

    Article

    Modelling and simulation of signal transductions in an apoptosis pathway by using timed Petri nets

    This paper first presents basic Petri net components representing molecular interactions and mechanisms of signalling pathways, and introduces a method to construct a Petri net model of a signalling pathway wi...

    Li Chen, Ge Qi-Wei, Mitsuru Nakata, Hiroshi Matsuno… in Journal of Biosciences (2007)

  19. No Access

    Article

    Association of genetic polymorphism inGH gene with milk production traits in Bei**g Holstein cows

    Associations were analysed between polymorphisms of the growth hormone gene (GH-MspI) (localized in intron 3) and milk production traits of Bei**g Holstein cows (a total of 543 cows). Polymerase chain reaction (...

    Guo Li Zhou, Hai Guo **, Chen Liu, Shan Li Guo, Qi Zhu… in Journal of Biosciences (2005)