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  1. Article

    Open Access

    An effective and chemotherapy-free strategy of all-trans retinoic acid and arsenic trioxide for acute promyelocytic leukemia in all risk groups (APL15 trial)

    The combination of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) has been demonstrated to have comparable effectiveness or better to ATRA and chemotherapy (CHT) in non-high-risk acute promyelocytic...

    Huai-Yu Wang, Sha Gong, Guo-Hui Li, Ya-Zhou Yao, Yin-Suo Zheng in Blood Cancer Journal (2022)

  2. Article

    Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections

    The clinical features and immune responses of asymptomatic individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been well described. We studied 37 asymptomatic indivi...

    Quan-**n Long, **ao-Jun Tang, Qiu-Lin Shi, Qin Li, Hai-Jun Deng in Nature Medicine (2020)

  3. Article

    Antibody responses to SARS-CoV-2 in patients with COVID-19

    We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG...

    Quan-**n Long, Bai-Zhong Liu, Hai-Jun Deng, Gui-Cheng Wu, Kun Deng in Nature Medicine (2020)

  4. Article

    Open Access

    RIPK4 promotes bladder urothelial carcinoma cell aggressiveness by upregulating VEGF-A through the NF-κB pathway

    Constitutively activated nuclear factor kappa B (NF-κB) signalling plays vital roles in bladder urothelial carcinoma (BC) progression. We investigate the effect of receptor-interacting protein kinase 4 (RIPK4)...

    Jian-Ye Liu, Qing-Hai Zeng, Pei-Guo Cao, Dan **e, **n Chen in British Journal of Cancer (2018)

  5. Article

    Open Access

    Medical expenses of urban Chinese patients with stomach cancer during 2002–2011: a hospital-based multicenter retrospective study

    In China, stomach cancer is the third most common cancer and the third leading cause of cancer death. Few studies have examined Chinese stomach cancer patients’ medical expenses and their associated trends. Th...

    **ao-Jie Sun, Ju-Fang Shi, Lan-Wei Guo, Hui-Yao Huang, Neng-Liang Yao in BMC Cancer (2018)

  6. Article

    Correction: Corrigendum: Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates

    Nat. Med. 23, 439–449 (2017); published online 20 February 2017; corrected after print 26 July 2017 In the version of this article initially published, the authors inadvertently left out information in the Onl...

    Pi-**ao Wang, Yan-**ao Ji, **ao-**g Zhang, Ling-** Zhao in Nature Medicine (2017)

  7. Article

    Open Access

    PKC α regulates netrin-1/UNC5B-mediated survival pathway in bladder cancer

    Netrin-1 and its receptor UNC5B play important roles in angiogenesis, embryonic development, cancer and inflammation. However, their expression patttern and biological roles in bladder cancer have not been wel...

    Jiao Liu, Chui-ze Kong, Da-xin Gong, Zhe Zhang, Yu-yan Zhu in BMC Cancer (2014)

  8. Article

    Open Access

    Characterization of genetic rearrangements in esophageal squamous carcinoma cell lines by a combination of M-FISH and array-CGH: further confirmation of some split genomic regions in primary tumors

    Chromosomal and genomic aberrations are common features of human cancers. However, chromosomal numerical and structural aberrations, breakpoints and disrupted genes have yet to be identified in esophageal squa...

    Jia-Jie Hao, Zhi-Zhou Shi, Zhi-**n Zhao, Yu Zhang, Ting Gong, Chun-**ang Li in BMC Cancer (2012)

  9. Article

    Open Access

    The efficacy of TACE combined sorafenib in advanced stages hepatocellullar carcinoma

    The long-term survival in hepatocellullar carcinoma (HCC) patients after transarterial chemoembolization (TACE) remains dismal due to local and/or regional recurrence as well as distant metastasis. The efficac...

    Xu-Dong Qu, Cheng-Shi Chen, Jian-Hua Wang, Zhi-** Yan, Jie-min Chen in BMC Cancer (2012)