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Human Infant Fecal Microbiota Differentially Influences the Mucosal Immune Pathways Upon Influenza Infection in a Humanized Gnotobiotic Pig Model
In this study, we evaluated the impact of human gut microbiota on the immune pathways in the respiratory tract using a gnotobiotic (Gn) piglet model....
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Establishing Host–Virus Link Through Host Metabolism: Viral DNA SIP Validation Using T4 Bacteriophage and E. coli
DNA Stable Isotope Probing is emerging as a potent methodology for investigating host–virus interactions, based on the essential reliance of viruses...
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Phase Equilibria of Binary Mixtures of 3-Chloro-2-Hydroxypropyl Methacrylate and 2-N-Morpholinoethyl Methacrylate in Supercritical Carbon Dioxide
This study presents exceptional perception into the phase transition behavior of binary mixtures containing 3-chloro-2-hydroxypropyl methacrylate...
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Effect of foliar application of plant growth regulators on expression of flowering genes in cucumber (Cucumis sativus L.)
Cucumber is an important horticultural crop grown globally and is cultivated under protected conditions. The formation of male and female flowers is...
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PIM1/NF-κB/CCL2 blockade enhances anti-PD-1 therapy response by modulating macrophage infiltration and polarization in tumor microenvironment of NSCLC
Elevated infiltration of tumor-associated macrophages (TAMs) drives tumor progression and correlates with poor prognosis for various tumor types. Our...
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Mechanistic Investigation on the Antibacterial Activity of Biogenic Silver Nanoparticles Prepared Using Root Extract of Sarsaparilla and Demonstrated their In Vivo Efficacy in Zebrafish Model
Antibiotic success rates are decreasing as drug-resistant bacteria become more prevalent, prompting the development of new therapeutic drugs. Herein,...
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An ensemble deep learning models approach using image analysis for cotton crop classification in AI-enabled smart agriculture
BackgroundAgriculture is one of the most crucial assets of any country, as it brings prosperity by alleviating poverty, food shortages, unemployment,...
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Development of Rapid Disk Diffusion Device Using Laser Speckle Formation Technology for Rapid Antimicrobial Susceptibility Testing
The escalation of antimicrobial resistance (AMR) due to the excessive and inappropriate use of antimicrobials has prompted the urgent need for more...
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Hemostasis and complement in allogeneic hematopoietic stem cell transplantation: clinical significance of two interactive systems
Hematopoietic stem cell transplantation (HCT) represents a curative treatment option for certain malignant and nonmalignant hematological diseases....
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Characterization of 13 Novel Genetic Variants in Genes Associated with Epilepsy: Implications for Targeted Therapeutic Strategies
BackgroundChildhood epilepsies are caused by heterogeneous underlying disorders where approximately 40% of the origins of epilepsy can be attributed...
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m1A demethylase Alkbh3 regulates neurogenesis through m1A demethylation of Mmp15 mRNA
BackgroundN 1 -Methyladenosine (m 1 A) is an abundant modification of transcripts regulating mRNA structure and translation efficiency. However, the...
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A versatile functional interaction between electrically silent KV subunits and KV7 potassium channels
Voltage-gated K + (K V ) channels govern K + ion flux across cell membranes in response to changes in membrane potential. They are formed by the assembly...
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Heterotopic ovarian transplantation instead hormonal replacement therapy after radical hysterectomy for cervical cancer: case report and review of literature
PurposeOnly a few case reports have described heterotopic ovarian tissue transplantation (OTT) with the only objective of restoring ovarian function.
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Light-mediated biosynthesis of size-tuned silver nanoparticles using Saccharomyces cerevisiae extract
Bio-based production of silver nanoparticles represents a sustainable alternative to commercially applied physicochemical manufacturing approaches...
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Computational Insights into Papaveroline as an In Silico Drug Candidate for Alzheimer’s Disease via Fyn Tyrosine Kinase Inhibition
Alzheimer’s disease (AD) poses a significant global health challenge, necessitating the exploration of novel therapeutic strategies. Fyn Tyrosine...
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The function of long non-coding RNA IFNG-AS1 in autoimmune diseases
The prevalence of autoimmune diseases ranks as the third most common disease category globally, following cancer and heart disease. Numerous studies...
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Prediction and map** the productivity of eucalyptus clones with environmental covariates
The quantitative nature of wood production poses a challenge for breeders. The complex interaction of genotypes with environments (G×E) makes...
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Effects of Commonly used Surfactants, Poloxamer 188 and Tween 80, on the Drug Transport Capacity of Intestinal Glucose Transporters
Some glycoside drugs can be transported through intestinal glucose transporters (IGTs). The surfactants used in oral drug preparations can affect the...
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The resistance switching performance of the memristor improved effectively by inserting carbon quantum dots (CQDs) for digital information processing
As an emerging information device that adapts to development of the big data era, memristor has attracted much attention due to its advantage in...
