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Birth weight and birth length affect future fracture risk differently in men and women
SummaryWe wanted to determine if there are any associations between birth factors and adult fracture risk. For women only, shorter birth length was...
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Clinical study on freehand of bicortical sacral screw fixation with the assistance of torque measurement device
BackgroundSacral screw loosening is a typical complication after internal fixation surgery through the vertebral arch system. Bicortical fixation can...
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Associations between new obesity indices and abnormal bone density in type 2 diabetes mellitus patients
SummaryThe clinical data analysis found that, compared with the traditional obesity index, the waist-weight ratio (WWR) has more advantages in...
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Spinal fusion surgery use among adults with low back pain enrolled in a digital musculoskeletal program: an observational study
ObjectivesTo compare 12-month spinal fusion surgery rates in the setting of low back pain among digital musculoskeletal (MSK) program participants...
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Potential association of rheumatic diseases with bone mineral density and fractures: a bi-directional mendelian randomization study
BackgroundPrevious studies have implicated rheumatoid arthritis as an independent risk factor for bone density loss. However, whether there is a...
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Differential Adherence to Free and Single-Pill Combination of Rosuvastatin/Ezetimibe: Findings from a Real-World Analysis in Italy
IntroductionAdherence to cardiovascular drug treatment can significantly benefit from a reduced pill burden, but data on this matter derived from...
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A quantitative comparison between the essential medicines for rheumatic diseases in children and young people in Africa and the WHO model list
BackgroundThe World Health Organisation Essential Medicines List (WHO EML) guides National Essential Medicines Lists and Standard Treatment...
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Comparing autologous blood, corticosteroid, and a combined injection of both for treating lateral epicondylitis: a randomized clinical trial
BackgroundBecause lateral epicondylitis is a common musculoskeletal disorder that affects the forearm's extensor tendons, an effective therapeutic...
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Effect of Hepatic Impairment on Trofinetide Exposures Using an In Silico Physiologically Based Pharmacokinetic Model
IntroductionTrofinetide is the first drug to be approved for the treatment of Rett syndrome. Hepatic impairment is not expected to affect the...
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Relationship between nailfold capillaroscopy findings and the etiology and prognosis of interstitial lung disease
ObjectivesConnective tissue-associated interstitial lung diseases (CTD-ILD) are believed to be caused by microvascular damage. The objective of this...
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Validation of the Geriatrics at Risk Score (GeRi-Score) on 120-day follow-up, the influence of preoperative geriatric visits, and the time to surgery on the outcome of hip fracture patients: an analysis from the Registry for Geriatric Trauma (ATR-DGU)
SummaryA validation of the GeRi-Score on 120-day mortality, the impact of a pre-operative visit by a geriatrician, and timing of surgery on the...
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Genetic polymorphisms in genes involved in the type I interferon system (STAT4 and IRF5): association with Asian SLE patients
Systemic lupus erythematosus (SLE) is a common autoimmune disease with a polymorphic clinical presentation involving multisystem damages with...
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Chemokine CXCL9, a marker of inflammaging, is associated with changes of muscle strength and mortality in older men
SummaryOur study examined associations of the CXC motif chemokine ligand 9 (CXCL9), a pro-inflammatory protein implicated in age-related...
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Treatment Strategies for Filamentous Fungi Keratitis
IntroductionThis research aims to describe clinical findings, epidemiology and treatment outcomes in patients with filamentous fungi keratitis of a...
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Race-specific FRAX models are evidence-based and support equitable care: a response to the ASBMR Task Force report on Clinical Algorithms for Fracture Risk
Task Force on ‘Clinical Algorithms for Fracture Risk’ commissioned by the American Society for Bone and Mineral Research (ASBMR) Professional...
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Alternate levels versus all levels mini-plate fixation in C3-6 cervical laminoplasty: a retrospective comparative study
ObjectiveThe purpose of this study is to compare radiological and clinical outcomes between alternate levels (C4 and C6) and all levels mini-plate...
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Gender Differences in Perceptions of Psoriatic Arthritis Disease Impact, Management, and Physician Interactions: Results from a Global Patient Survey
IntroductionWe evaluated the impact of gender on disease severity, health-related quality of life (HRQoL), treatment management, and...
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Feasibility of Indirect Treatment Comparisons Between Niraparib Plus Abiraterone Acetate and Other First-Line Poly ADP-Ribose Polymerase Inhibitor Treatment Regimens for Patients with BRCA1/2 Mutation-Positive Metastatic Castration-Resistant Prostate Cancer
IntroductionPoly(ADP-ribose) polymerase inhibitors (PARPi) are a novel option to treat patients with metastatic castration-resistant prostate cancer...
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Development of a brief core set for knee dysfunction based on the International Classification of Functioning, Disability and Health: assessing construct validity and measurement potential
BackgroundThe comprehensive core set for knee dysfunction was developed to classify the functioning of people with any knee dysfunction. To be used...