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3,205 Result(s)
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Article
Large-scale whole-exome sequencing of neuropsychiatric diseases and traits in 350,770 adults
While numerous genomic loci have been identified for neuropsychiatric conditions, the contribution of protein-coding variants has yet to be determined. Here we conducted a large-scale whole-exome-sequencing st...
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Open AccessClinicopathologic Features and Cytologic Correlation of ALK-Rearranged Papillary Thyroid Carcinoma: A Series of Eight Cases
Anaplastic lymphoma kinase (ALK) gene fusions are rare in papillary thyroid carcinoma (PTC) but may serve as a therapeutic target. This study aims to evaluate the preoperative cytologic findings and clinicopathol...
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Impact of Skeletal Muscle Loss and Sarcopenia on Outcomes of Locally Advanced Esophageal Cancer during Neoadjuvant Chemoradiation
The impact of changes in skeletal muscle and sarcopenia on outcomes during neoadjuvant chemoradiotherapy (NACR) for patients with esophageal cancer remains controversial.
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Open AccessLink Brain-Wide Projectome to Neuronal Dynamics in the Mouse Brain
Knowledge about the neuronal dynamics and the projectome are both essential for understanding how the neuronal network functions in concert. However, it remains challenging to obtain the neural activity and th...
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Open AccessResource theory of imaginarity in distributed scenarios
The resource theory of imaginarity studies the operational value of imaginary parts in quantum states, operations, and measurements. Here we introduce and study the distillation and conversion of imaginarity i...
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Open AccessTwo-dimensional materials for future information technology: status and prospects
Over the past 70 years, the semiconductor industry has undergone transformative changes, largely driven by the miniaturization of devices and the integration of innovative structures and materials. Two-dimensi...
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Open AccessPolyurethane-based three-dimensional printing for biological mesh carriers
Repair and reconstruction of the myopectineal orifice area using meshes is the mainstay of surgical treatment of inguinal hernias. However, the limitations of existing meshes are becoming increasingly evident ...
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Open AccessSurvival and disease burden analyses of occupational pneumoconiosis during 1958–2021 in Huangshi city, China: a retrospective cohort study
Pneumoconiosis, a chronic disease stemming from prolonged inhalation of dust particles, stands as a significant global burden of occupational diseases. This study aims to investigate the survival outcomes of p...
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Open AccessMeasurement of t-channel production of single top quarks and antiquarks in pp collisions at 13 TeV using the full ATLAS Run 2 data sample
The production of single top quarks and top antiquarks via the t-channel exchange of a virtual W boson is measured in proton-proton collisions at a centre-of-mass energy of 13 TeV at the LHC using 140 fb−1 of ATL...
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Open AccessSearch for a third-generation leptoquark coupled to a τ lepton and a b quark through single, pair, and nonresonant production in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search is presented for a third-generation leptoquark (LQ) coupled exclusively to a τ lepton and a b quark. The search is based on proton-proton collision data at a center-of-mass energy of 13 TeV recorded w...
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Open AccessABA-mediated regulation of rice grain quality and seed dormancy via the NF-YB1-SLRL2-bHLH144 Module
Abscisic acid (ABA) plays a crucial role in promoting plant stress resistance and seed dormancy. However, how ABA regulates rice quality remains unclear. This study identifies a key transcription factor SLR1-l...
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Structural engineering of hard carbon through spark plasma sintering for enhanced sodium-ion storage
Hard carbon (HC) has emerged as one of the superior anode materials for sodium-ion batteries (SIBs), with its electrochemical performance significantly influenced by the presence of oxygen functional groups an...
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Grain boundary-induced drastic sensing performance enhancement of Fe2O3 gas sensors for acetone
Exploring the structure–activity relationship between the performance of gas sensors and the structure of semiconductor metal oxide (SMO) nanomaterials is crucial for understanding and designing gas-sensing ma...
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Autologous material-inspired drug delivery systems
Pursuing personalized medicine has spurred the development of drug delivery systems inspired by autologous materials, underscoring the transition from natural origins to medicinal applications. The allure of a...
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Open AccessFerritinophagy mediates adaptive resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer
Osimertinib (Osi) is a widely used epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). However, the emergence of resistance is inevitable, partly due to the gradual evolution of adaptive res...
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Bevacizumab induces ferroptosis and enhances CD8+ T cell immune activity in liver cancer via modulating HAT1 and increasing IL-9
Bevacizumab is a recombinant humanized monoclonal immunoglobulin (Ig) G1 antibody of VEGF, and inhibits angiogenesis and tumor growth in hepatocellular carcinoma (HCC). Ferroptosis, a new form of regulated cel...
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Open AccessSearch for electroweak production of supersymmetric particles in final states with two τ-leptons in \( \sqrt{s} \) = 13 TeV pp collisions with the ATLAS detector
Three searches for the direct production of τ-sleptons or charginos and neutralinos in final states with at least two hadronically decaying τ-leptons are presented. For chargino and neutralino production, decays ...
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Open AccessMeasurement of the total and differential cross-sections of \( t\overline{t}W \) production in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
Measurements of inclusive and differential production cross-sections of a top-quark-top-antiquark pair in association with a W boson ( ...
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Experimental quantum state compression from two identical qubits to a qutrit
In the realm of modern information technology, data compression technology occupies a pivotal position. With advancements in quantum information technology, the need to compress large-scale qubits ensembles ha...
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Open AccessPharmaceutical treatment status of patients with COPD in the community based on medical Internet of Things: a real-world study
This study aimed to investigate the real-world standardisation and adherence of medical treatment regimens in patients with chronic obstructive pulmonary disease (COPD) in the community for making future manag...