115 Result(s)

Article

Vaginal dose of radical radiotherapy for cervical cancer in China: a multicenter study

The posterior-inferior border of symphysis (PIBS) point system is a novel vaginal dose-reporting method and is a simple and reliable method proposed by the Medical University of Vienna proposed for both extern...

Juan Wang, Kai-shuo Zhang, Tao Wang, Zi Liu, Rui-hua Wang, Fu-quan Zhang… in BMC Cancer (2019)

Article

Optimal sequencing of chemotherapy with chemoradiotherapy based on TNM stage classification and EBV DNA in locoregionally advanced nasopharyngeal carcinoma

Li-Ting Liu, Melvin L. K. Chua, Yungan Tao, Lin-Quan Tang… in Cancer Communications (2019)

Article

Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats

Central sensitization plays a pivotal role in the maintenance of chronic pain induced by chronic pancreatitis (CP), but cortical modulation of painful CP remains elusive. This study was designed to examine the...

Yang Bai, Li-Tian Ma, Yan-Bing Chen, Dan Ren, Ying-Biao Chen, Ying-Qi Li… in Molecular Brain (2019)

Article

The effects of autophagy on the replication of Nelson Bay orthoreovirus

Nelson Bay orthoreovirus (NBV) was first isolated over 40 years ago from a fruit bat in Australia. Normally, NBV does not cause human diseases, but recently several NBV strains have been associated with human ...

**ao-Li Tao, Wei Zhao, Wei Tong, **ao-Fang Wang, Li-Li Dou… in Virology Journal (2019)

Article

Clinical features and genetic spectrum in Chinese patients with recessive hereditary spastic paraplegia

Although many causative genes of hereditary spastic paraplegia (HSP) have been uncovered in recent years, there are still approximately 50% of HSP patients without genetically diagnosis, especially in autosoma...

Qiao Wei, Hai-Lin Dong, Li-Ying Pan, Cong-**n Chen… in Translational Neurodegeneration (2019)

Article

Correlations between quantitative parameters of contrast-enhanced ultrasound and vasculogenic mimicry in murine tumor model: a novel noninvasive technique for assessment?

Vasculogenic mimicry (VM) is a novel mechanism of tumor blood supply distinct from endothelial vessel (EV). VM is associated with malignancy, invasion, metastasis, and poor prognosis. Hitherto a noninvasive me...

Yue-tao Zhou, Wei-wei Cai, Yue Li, **ao Jiang, Lei Feng… in Biological Procedures Online (2019)

Article

β-Asarone increases doxorubicin sensitivity by suppressing NF-κB signaling and abolishes doxorubicin-induced enrichment of stem-like population by destabilizing Bmi1

Lymphoma is one of the most common hematologic malignancy. Drug resistance is the main obstacle faced in lymphoma treatment. Cancer stem cells are considered as the source of tumor recurrence, metastasis and d...

Li-Na Lv, **ao-Chao Wang, Li-Ju Tao, Hong-Wen Li, Shu-You Li… in Cancer Cell International (2019)

Article

microRNA-328 in exosomes derived from M2 macrophages exerts a promotive effect on the progression of pulmonary fibrosis via FAM13A in a rat model

Currently, exosome-enclosed microRNAs (miRs) in exhaled breath have potential for biomarker discovery in patients with pulmonary diseases. This study was performed to investigate the roles of M2 macrophage-der...

Meng-Ying Yao, Wei-Hong Zhang, Wen-Tao Ma… in Experimental & Molecular Medicine (2019)

Article

Bioinformatics-based discovery of the urinary BBOX1 mRNA as a potential biomarker of diabetic kidney disease

Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease (ESKD) in the world. Emerging evidence has shown that urinary mRNAs may serve as early diagnostic and prognostic biomarkers of DKD...

Le-Ting Zhou, Lin-Li Lv, Shen Qiu, Qing Yin… in Journal of Translational Medicine (2019)

Article

Protist communities are more sensitive to nitrogen fertilization than other microorganisms in diverse agricultural soils

Agricultural food production is at the base of food and fodder, with fertilization having fundamentally and continuously increased crop yield over the last decades. The performance of crops is intimately tied ...

Zhi-Bo Zhao, Ji-Zheng He, Stefan Geisen, Li-Li Han, Jun-Tao Wang, Ju-Pei Shen… in Microbiome (2019)

Article

AMPK activation attenuates inflammatory pain through inhibiting NF-κB activation and IL-1β expression

Chronic pain is a major clinical problem with limited treatment options. Previous studies have demonstrated that activation of adenosine monophosphate-activated protein kinase (AMPK) can attenuate neuropathic ...

Hong-Chun **ang, Li-Xue Lin, Xue-Fei Hu, He Zhu… in Journal of Neuroinflammation (2019)

Article

Germline TP53 and MSH6 mutations implicated in sporadic triple-negative breast cancer (TNBC): a preliminary study

Germline BRCA1/2 prevalence is relatively low in sporadic triple-negative breast cancer (TNBC). We hypothesized that non-BRCA genes may also have significant germline contribution to Chinese sporadic TNBC, and...

Dandan Yi, Lei Xu, Jiaqi Luo, **aobin You, Tao Huang, Yi Zi, **aoting Li… in Human Genomics (2019)

Article

Overexpression of chloride channel-3 (ClC-3) is associated with human cervical carcinoma development and prognosis

Cervical carcinoma is a major gynecological cancer and causes cancer-related deaths in worldwide, the latent pathogenesis and progress of cervical cancer is still under research. ClC-3 may be an important prom...

Yu-tao Guan, Yong **e, Hui Zhou, Hai-yan Shi, Yu-yuan Zhu… in Cancer Cell International (2019)

Article

Early goal-directed and lactate-guided therapy in adult patients with severe sepsis and septic shock: a meta-analysis of randomized controlled trials

The ProCESS, ARISE, and ProMISe trials have failed to show that early goal-directed therapy (EGDT) reduces mortality in patients with severe sepsis and septic shock. Although lactate-guided therapy (LGT) has b...

**an-Fei Ding, Zi-Yue Yang, Zhen-Tao Xu, Li-Feng Li… in Journal of Translational Medicine (2018)

Article

The chemodiversity of paddy soil dissolved organic matter correlates with microbial community at continental scales

Paddy soil dissolved organic matter (DOM) represents a major hotspot for soil biogeochemistry, yet we know little about its chemodiversity let alone the microbial community that shapes it. Here, we leveraged u...

Hong-Yi Li, Hang Wang, Hai-Tao Wang, Pei-Yong **n, **n-Hua Xu, Yun Ma… in Microbiome (2018)

Article

Retraction Note: Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis

The authors are retracting this article [1] after an investigation by the Ethics Committee of the Fourth Military Medical University (**’an, Shaanxi, China) of the following concerns that had been raised with ...

Jun-Tang Li, Li-Feng Wang, Ya-Li Zhao, Tao Yang, Wei Li… in Breast Cancer Research (2018)

Article

Adefovir dipivoxil induced hypophosphatemic osteomalacia in chronic hepatitis B: a comparative study of Chinese and foreign case series

Adefovir dipivoxil (ADV)-induced renal tubular dysfunction and hypophosphatemic osteomalacia (HO) have been given great consideration in the past few years. However, no standard guidance is available due to a ...

Nan Chen, Jian-bo Zhang, Qiujie Zhang, Yun-peng Zhao… in BMC Pharmacology and Toxicology (2018)

Article

Long-term outcomes of endoscopic submucosal dissection for high-grade dysplasia and early-stage carcinoma in the colorectum

Colorectal carcinomas (CRCs) arise from premalignant precursors in an adenoma-carcinoma sequence, in which adenoma with high-grade dysplasia (HGD) and early-stage carcinoma are defined as advanced neoplasia. A...

Tao Chen, Wen-Zheng Qin, Li-Qing Yao, Yun-Shi Zhong, Yi-Qun Zhang… in Cancer Communications (2018)

Article

Akt/FoxM1 signaling pathway-mediated upregulation of MYBL2 promotes progression of human glioma

MYB-related protein B (B-MYB/MYBL2), a member of the myeloblastosis family of transcription factors, has been reported for its role in the genesis and progression of tumors. Forkhead box M1 (FoxM1), another tr...

Xue Zhang, Qiao-Li LV, Yuan-Tao Huang… in Journal of Experimental & Clinical Cancer … (2017)

Article

Molecular mechanism of G₁ arrest and cellular senescence induced by LEE011, a novel CDK4/CDK6 inhibitor, in leukemia cells

Overexpression of cyclin D1 dependent kinases 4 and 6 (CDK4/6) is a common feature of many human cancers including leukemia. LEE011 is a novel inhibitor of both CDK4 and 6. To date, the molecular function of L...

Yan-Fang Tao, Na-Na Wang, Li-**ao Xu, Zhi-Heng Li, **ao-Lu Li… in Cancer Cell International (2017)