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  1. No Access

    Article

    ASIP genetic variants and the number of non-melanoma skin cancers

    Patients with primary non-melanoma skin cancers (NMSCs) tend to develop these cancers at multiple independent sites. We examined the genetic factors in the development of multiple NMSCs among Caucasian women w...

    Wen Lin, Abrar A. Qureshi, Peter Kraft, Hongmei Nan, Qun Guo in Cancer Causes & Control (2011)

  2. No Access

    Article

    Genetic variants in telomere-maintaining genes and skin cancer risk

    Telomere-related genes play an important role in maintaining the integrity of the telomeric structure that protects chromosome ends, and telomere dysfunction may lead to tumorigenesis. We evaluated the associa...

    Hongmei Nan, Abrar A. Qureshi, Jennifer Prescott, Immaculata De Vivo in Human Genetics (2011)

  3. No Access

    Article

    Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk

    Mistakes in DNA repair can result in sustained damage and genetic instability. We comprehensively evaluated common variants in DNA repair pathway genes for their association with postmenopausal breast cancer r...

    Genevieve M. Monsees, Peter Kraft in Breast Cancer Research and Treatment (2011)

  4. Article

    Open Access

    Genetic variants in FGFR2 and FGFR4 genes and skin cancer risk in the Nurses' Health Study

    The human fibroblast growth factor (FGF) and its receptor (FGFR) play an important role in tumorigenesis. Deregulation of the FGFR2 gene has been identified in a number of cancer sites. Overexpression of the FGFR...

    Hongmei Nan, Abrar A Qureshi, David J Hunter, Jiali Han in BMC Cancer (2009)

  5. No Access

    Article

    Genetic variation in DNA repair pathway genes and premenopausal breast cancer risk

    Purpose We comprehensively evaluated genetic variants in DNA repair genes with premenopausal breast cancer risk. Methods In this nested case–control study of 239 prospectively ascertained premenopausal breast can...

    Jiali Han, Christopher Haiman, Tianhua Niu, Qun Guo in Breast Cancer Research and Treatment (2009)

  6. No Access

    Article

    A functional SNP in the MDM2 promoter, pigmentary phenotypes, and risk of skin cancer

    The MDM2 oncoprotein is a key negative regulator of the tumor suppressor p53. A functional MDM2 single nucleotide polymorphism (SNP309) in the promoter region increases the affinity of transcription activator ...

    Hongmei Nan, Abrar A. Qureshi, David J. Hunter, Jiali Han in Cancer Causes & Control (2009)

  7. No Access

    Article

    A prospective study of genetic polymorphism in MPO, antioxidant status, and breast cancer risk

    Oxidative stress may be involved in breast carcinogenesis. Myeloperoxidase (MPO) is an endogenous oxidant enzyme that generates reactive oxygen species (ROS). A single nucleotide polymorphism (SNP) G-463A in t...

    Chunyan He, Rulla M. Tamimi, Susan E. Hankinson in Breast Cancer Research and Treatment (2009)

  8. No Access

    Article

    Manganese superoxide dismutase polymorphism and risk of skin cancer (United States)

    We assessed whether the functional V16A polymorphism in the MnSOD gene is associated with skin cancer risk.

    Jiali Han, Graham A. Colditz, David J. Hunter in Cancer Causes & Control (2007)

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