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Article
Open AccessAtypical anti-glomerular basement membrane disease with membranous hyperplasia: diagnostic challenges and treatment variability
This case report presents a detailed analysis of a 31-year-old male patient who presented with a complex array of clinical symptoms, including proteinuria, hematuria, edema, and kidney insufficiency. Despite u...
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Article
Open AccessThe polymorphism analysis for CD36 among platelet donors
CD36 may defect on platelets and/or monocytes in healthy individuals, which was defined as CD36 deficiency. However, we did not know the correlation between the molecular and protein levels completely. Here, w...
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Article
Cation substitution for enhanced pseudocapacitance performance of spinel bimetallic sulfides porous nanowires for increased energy storage
The utilization of cation substitution presents a prospective approach to manipulate the structural characteristics and enhance the electrochemical functionality of spinel cobaltous sulfide (Co3S4). However, the ...
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Article
Reductive lipid nanoparticles loaded with vinorelbine inhibit chemotherapy-induced invasion of cancer cells by modulating ENPP2
Cancer is a predominant culprit behind worldwide death and accounts for up to 10 million deaths every year. Chemotherapy is the primary therapeutic method employed for cancer in clinical settings and is essent...
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Article
PCSK9 regulates myocardial ischemia–reperfusion injury through parkin/pink1-mediated autophagy pathway
This study aimed at investigating the role of the proprotein convertase subtilisin/Kexin type 9 (PCSK9)-mediated autophagy on myocardial ischemia/reperfusion injury (MIRI). To determine the relationship betwee...
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Article
Ship**-related pollution decreased but mortality increased in Chinese port cities
The maritime industry boosts the prosperity of port cities but also exacerbates premature death associated with air pollution. In recent years, Chinese port cities have undergone profound multifaceted transfor...
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Article
Open AccessUnsupervised learning of optical flow in a multi-frame dynamic environment using temporal dynamic modeling
For visual estimation of optical flow, which is crucial for various vision analyses, unsupervised learning by view synthesis has emerged as a promising alternative to supervised methods because the ground-trut...
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Article
Peptide-mimicking poly(2-oxazoline)s as adjuvants to enhance activities and antibacterial spectrum of polymyxin B
Antibiotic-resistant ESKAPE bacteria have become a significant threat to human health due to the ineffectiveness of clinically used broad-spectrum antibiotics. Combination therapy of antibiotic and adjuvant ha...
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Article
Effects of Heat Treatment on Microstructure, Mechanical Properties, and Residual Stress of Oscillation Laser–Tungsten Inert Gas Hybrid Welded Joints for SA-738Gr.B Steel
This paper adopted the new process of double-sided oscillation laser autogenous backing welding and double-sided oscillation laser–TIG hybrid filling welding to achieve 80 mm thick SA-738Gr.B steel narrow gap ...
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Article
Benefit of structural access panels (SAP) for post-earthquake structural health monitoring
This paper develops a method to quantify the benefit of using structural access panels (SAPs) placed in internal partition walls (IPWs) or ceilings near the dissipative elements of structures for post-earthqua...
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Article
Factors and Their Impact on Treatment Effect of Acupuncture in Different Outcomes: A Meta-Regression of Acupuncture Randomized Controlled Trials
The effects of acupuncture have varied in different randomized controlled trials (RCTs), and there are many factors that influence treatment effect of acupuncture in different outcomes, with conflicting results.
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Article
Open AccessAssessing the effectiveness of Interleukin-2 therapy in experimental type 1 diabetes
Much focus of immunotherapy for type 1 diabetes (T1D) has been devoted on selectively boosting regulatory T (Treg) cells using low dose IL-2 due to their constitutive expression of IL-2Rα, CD25. However, sever...
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Article
Investigation of Nutrition and Printability of Orange Juice Sacs Applied to Heterogeneous 3D Printing: Influence of Pretreatment-Assisted Impregnation
The osmotically dehydrated orange juice sacs can serve as materials for heterogeneous 3D printing. Moreover, physical field-assisted such as ultrasound and vacuum, along with their combined application, were e...
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Article
Open AccessPorphyromonas gingivalis aggravates colitis via a gut microbiota-linoleic acid metabolism-Th17/Treg cell balance axis
Periodontitis is closely related to inflammatory bowel disease (IBD). An excessive and non-self-limiting immune response to the dysbiotic microbiome characterizes the two. However, the underlying mechanisms th...
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Article
Open AccessThe innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer
Lung cancer, a prevalent and aggressive disease, is characterized by recurrence and drug resistance. It is essential to comprehend the fundamental processes and discover novel therapeutic objectives for augmen...
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Article
Experimental Study on Failure Mode of Precast Assembled Segmental Beams under Impact Loading
Precast segmental girder bridges are threatened by impact loads during service, but there is currently little research on the impact behavior of such bridges. This study investigated the dynamic responses and ...
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Article
TFTSVM: near color recognition of polishing red lead via SVM based on threshold and feature transform
With the extensive application of machine vision in the manufacturing industry, target region recognition in complex industrial scenes is becoming a vital research territory. In the automatic polishing of mold...
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Article
Effect of PA6 coating on the ultrasonic welding of CF/PA66 to 6061 aluminum alloy
Carbon fiber-reinforced thermoplastic composites (CFRTPs) are widely used in industrial manufacturing due to their excellent mechanical properties, and the joining of lightweight metal/CFRTP hybrid structure h...
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Article
Nonlinear dynamic analysis of the graphene platelets reinforced porous plate with magneto-electro-elastic sheets subjected to impact load
This paper studies the nonlinear dynamic characteristics of the simply supported and clamped graphene platelets reinforced porous plates with magneto-electro-elastic (MEE) sheets (GPLRP-MEE) subjected to axial...
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Article
Effect and Mechanism of Rare Earth Hydrotalcite Inhibiting Coal Spontaneous Combustion
A hydrotalcite(layered double hydroxide, LDH) inhibitor which is suitable for the whole process of coal spontaneous combustion and a LDH inhibitor containing rare earth lanthanum elements were prepared. The in...
