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Yu-** Hung
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Article
Open AccessA distinct dimer configuration of a diatom Get3 forming a tetrameric complex with its tail-anchored membrane cargo
Most tail-anchored (TA) membrane proteins are delivered to the endoplasmic reticulum through a conserved posttranslational pathway. Although core mechanisms underlying the targeting and insertion of TA protein...
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Open AccessIn situ HER2 RNA expression as a predictor of pathologic complete response of HER2-positive breast cancer patients receiving neoadjuvant chemotherapy and anti-HER2 targeted treatment
Immunohistochemistry (IHC) and in situ hybridization (ISH) remain standard biomarkers for therapeutic decisions in human epidermal growth factor 2 (HER2)-positive breast cancers (BCs); however, they are insuff...
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Integrating online partial pair programming and socially shared metacognitive regulation for the improvement of students’ learning
Many universities around the world were forced to lock down and students had to continue their learning in online environments in response to the COVID-19 pandemic. Teachers thus had to adopt effective and app...
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Incidence trends for common subtypes of T-cell lymphoma in Taiwan and the United States from 2008–2020
The incidence of T-cell lymphoma (TCL) has been continually increasing in Taiwan and the United States (US) in recent years. This epidemiological study using population-based registry data aimed to determine t...
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Open AccessSacubitril/valsartan improves all-cause mortality in heart failure patients with reduced ejection fraction and chronic kidney disease
Impaired renal function is frequently observed in patients with heart failure and reduced ejection fraction (HFrEF). The differential effect of sacubitril/valsartan and angiotensin-converting enzyme inhibitors...
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Open AccessGenetic mutation patterns among glioblastoma patients in the Taiwanese population – insights from a single institution retrospective study
This study utilized Next-Generation Sequencing (NGS) to explore genetic determinants of survival duration in Glioblastoma Multiforme (GBM) patients. We categorized 30 primary GBM patients into two groups based...
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Evolution of grain and ripple structures on the surface of aluminum parts fabricated by laser foil printing process at preheat temperatures
In this study, the evolution of grain and ripple structures on the surface of 6061 aluminum alloy (AA6061) parts fabricated by a laser-foil-printing (LFP) additive manufacturing process at different preheated ...
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Thromboprophylaxis for outpatients with COVID-19: a Systematic Review and Meta-analysis
Patients with COVID-19 develop an increased risk of thromboembolism. Thromboprophylaxis is recommended for hospitalized COVID-19 patients, but the role of thromboprophylaxis in outpatients with COVID-19 is les...
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Open AccessEpidemiology, Patient Characteristics, and Treatment Patterns of Myasthenia Gravis in Taiwan: A Population-Based Study
Myasthenia gravis (MG) is a chronic neuromuscular disease leading to significant disease burden. This study aimed to investigate the epidemiology of MG in Taiwan.
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Depressive status moderates the association between cognitive ability and psychological resilience in young adults
Associations among cognitive ability, depressive symptoms, and psychological resilience have been found, but the interaction among these variables remains unclear, especially for young adults. The current stud...
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Open AccessLiver Resection Criteria for Patients with Hepatocellular Carcinoma and Multiple Tumors Based on Total Tumor Volume
In many Asian hepatocellular carcinoma (HCC) guidelines, resection is an option for multiple HCCs. It is difficult to compare small but multiple tumors vs. fewer large tumors in terms of the traditional tumor ...
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Open AccessPopulation-Based Prognostic Models for Head and Neck Cancers Using National Cancer Registry Data from Taiwan
This study aims to raise awareness of the disparities in survival predictions among races in head and neck cancer (HNC) patients by develo** and validating population-based prognostic models specifically tai...
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Open AccessEfficacy and acceptability of different probiotic products plus laxatives for pediatric functional constipation: a network meta-analysis of randomized controlled trials
The prevalence of pediatric constipation ranges from 0.7 to 29.6% across different countries. Functional constipation accounts for 95% of pediatric constipation, and the efficacy of pharmacotherapy is limited,...
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Open AccessCorrelation between higher lateral tibial slope and inferior long term subjective outcomes following single bundle anterior cruciate ligament reconstruction
The impact of anatomical factors, such as the lateral tibial slope (LTS), on outcomes following anterior cruciate ligament (ACL) reconstruction is an area of growing interest. This study was led by the observa...
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Open AccessInvasive pulmonary aspergillosis among patients with severe community-acquired pneumonia and influenza in ICUs: a retrospective cohort study
The prevalence, clinical characteristics, and outcomes of invasive pulmonary aspergillosis in patients with severe community-acquired pneumonia (CAP) in intensive care units remain underestimated because of th...
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Open AccessAssociation between sodium–glucose cotransporter-2 (SGLT2) inhibitors and macular degeneration in patients with diabetes: a nationwide population-based study in Taiwan
Evidence showed that SGLT2 inhibitors have greater protective effects against retinal diseases compared to other hypoglycemic agents. Thus, we explore the association between SGLT2 inhibitor usage and macular ...
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Open AccessWhite matter alterations and their associations with biomarkers and behavior in subjective cognitive decline individuals: a fixel-based analysis
Subjective cognitive decline (SCD) is an early stage of dementia linked to Alzheimer's disease pathology. White matter changes were found in SCD using diffusion tensor imaging, but there are known limitations ...
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Open AccessAuthor Correction: Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity
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Open AccessStellae-123 gene expression signature improved risk stratification in Taiwanese acute myeloid leukemia patients
The European Leukemia Net recommendations provide valuable guidance in treatment decisions of patients with acute myeloid leukemia (AML). However, the genetic complexity and heterogeneity of AML are not fully ...
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Open AccessTwo-dimensional metal–organic framework for post-synthetic immobilization of graphene quantum dots for photoluminescent sensing
Immobilization of graphene quantum dots (GQDs) on a solid support is crucial to prevent GQDs from aggregation in the form of solid powder and facilitate the separation and recycling of GQDs after use. Herein, ...
