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Article
Strain difference in pulmonary vascular responsiveness to hypoxia in rats
The difference in pulmonary vascular response to hypoxia between Hilltop Sprague-Dawley (HT) rats and Wistar (W) rats was studied. Effects of inhibitor of leukotriene (LT) synthesis or prostaglandin (PG) synth...
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Article
Effects of cigarette smoking on hemodynamics and hypoxic pulmonary vasoconstriction: Role of prostaglandins and leukotrienes
This study investigated the role of prostaglandins (PGs) and leukotrieres (LTs) in hypoxic pulmonary vasoconstriction (HPV) and in cigarette smoking-induced changes in hemodynamics and HPV in Wistar rats. Sele...
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Article
Wirkung der Lipoxygenase- und Cyclooxygenase-Metaboliten auf die akute hypoxische pulmonale Vasokonstriktion beim Schweinchen
Durch am Schweinchen durchgeführte Versuche wurde nachgewiesen, daß die akute alveoläre Hypox ie starke pulmonale Vasokonstriktion mit Erhöhung des Herzzeitvolumens hervorrufen kann. Die pulmonale vasokonstrik...
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Article
Sympathetic innervation of pulmonary circulation and its role in hypoxic pulmonary vasoconstriction
The purposes of this study were to localize the position of spinal center of sympathetic nerve which controls the pulmonary circulation, and to evaluate the role of pulmonary sympathetic nerve in hypoxic pulmo...
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Article
The role of leukotrienes in acute hypoxic pulmonary vasoconstriction in rats
In this study, we investigated the possible role of leukotrienes in the mediation of hypoxic pulmonary vasoconstriction (HPV) in rats. Diethylcarbamazine citrate (DEC), an inhibitor of leukotriene synthesis, c...
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Article
Effect of tetramethylpyrazine on acute and chronic hypoxic pulmonary hypertension of the rat
The effect of tetramethylpyrazine (TMPZ) on acute as well as chronic hypoxic pulmonary hypertension has been studied in rats. TMPZ inhibited acute hypoxic pulmonary vasoconstriction and prevented chronic hypox...
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Article
Die Anwendung der Impedanz-Pulmonal-Rheographie zur Abschätzung des Pulmonalarteriendruckes — eine unblutige Methode
Bei 105 Patienten wurde während der Rechtsherzkatheteruntersuchung gleichzeitig das Impedanz-Pulmonal-Rheogramm (IPR) registriert. Die Korrelation zwischen dem Mitteldruck der Arteria pulmonalis {fx193-01} und...
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Article
The role of histamine in acute hypoxic pulmonary hypertension in dogs
The role of histamine in acute hypoxic pulmonary hypertension was studied in dogs, and the correlation between the effect of histamine and the characteristics of hypoxic pulmonary response was examined. Acute ...