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  1. Article

    Open Access

    Myelodysplasia is in the niche: novel concepts and emerging therapies

    Myelodysplastic syndromes (MDSs) represent clonal disorders mainly of the elderly that are characterized by ineffective hematopoiesis and an increased risk of transformation into acute myeloid leukemia. The pa...

    E Bulycheva, M Rauner, H Medyouf, I Theurl, M Bornhäuser, L C Hofbauer in Leukemia (2015)

  2. Article

    Open Access

    Relationship of different platelet response criteria and patient outcomes in a romiplostim myelodysplastic syndromes trial

    U Platzbecker, M A Sekeres, H Kantarjian, A Giagounidis, G J Mufti, C Jia in Leukemia (2014)

  3. No Access

    Article

    Low frequency of calreticulin mutations in MDS patients

    M Heuser, V Panagiota, C Koenecke, B Fehse, H Alchalby, A Badbaran, R Shahswar in Leukemia (2014)

  4. No Access

    Article

    Prognostic effect of calreticulin mutations in patients with myelofibrosis after allogeneic hematopoietic stem cell transplantation

    V Panagiota, F Thol, B Markus, B Fehse, H Alchalby, A Badbaran, U Lehmann in Leukemia (2014)

  5. No Access

    Article

    Impact of the revised International Prognostic Scoring System on the outcome of patients with acute myeloid leukemia with or without antecedent myelodysplastic syndrome

    F Stölzel, M Kramer, B Mohr, M Wermke, M Bornhäuser, G Ehninger, M Schaich in Leukemia (2014)

  6. No Access

    Article

    Phase 2 study of oral panobinostat (LBH589) with or without erythropoietin in heavily transfusion-dependent IPSS low or int-1 MDS patients

    U Platzbecker, H K Al-Ali, N Gattermann, D Haase, V Janzen, J Krauter, K Götze in Leukemia (2014)

  7. No Access

    Article

    SETBP1 mutation analysis in 944 patients with MDS and AML

    F Thol, K J Suchanek, C Koenecke, M Stadler, U Platzbecker, C Thiede in Leukemia (2013)

  8. No Access

    Article

    Early intervention with allogeneic hematopoietic cell transplantation during chemotherapy-induced aplasia in patients with high-risk acute myeloid leukemia

    F Stölzel, U Platzbecker, B Mohr, C Röllig, J M Middeke, C Thiede, M Füssel in Leukemia (2013)

  9. No Access

    Article

    Salvage therapy with azacitidine increases regulatory T cells in peripheral blood of patients with AML or MDS and early relapse after allogeneic blood stem cell transplantation

    T Schroeder, J Fröbel, R-P Cadeddu, A Czibere, A Dienst, U Platzbecker, G Bug in Leukemia (2013)

  10. No Access

    Article

    Combination of Azacitidine and Lenalidomide in Myelodysplastic Syndromes or acute Myeloid Leukemia—a wise Liaison?

    Treatment options for older patients with advanced myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) are limited and the prognosis remains poor, thereby warranting development of novel therapies....

    U Platzbecker, U Germing in Leukemia (2013)

  11. Article

    Open Access

    Azacytidine impairs NK cell activity in AML and MDS patients undergoing MRD-based pre-emptive treatment after allogeneic stem cell transplantation

    C Schönefeldt, K Sockel, R Wehner, S Sopper, D Wolf, M Wermke in Blood Cancer Journal (2013)

  12. Article

    Open Access

    Sequential combination of azacitidine and lenalidomide in del(5q) higher-risk myelodysplastic syndromes or acute myeloid leukemia: a phase I study

    U Platzbecker, F Braulke, A Kündgen, K Götze, G Bug, C Schönefeldt in Leukemia (2013)

  13. No Access

    Article

    Azacitidine and donor lymphocyte infusions as first salvage therapy for relapse of AML or MDS after allogeneic stem cell transplantation

    The combination of azacitidine and donor lymphocyte infusions (DLI) as first salvage therapy for relapse after allogeneic transplantation (allo-HSCT) was studied in 30 patients with acute myeloid leukemia (AML; n

    T Schroeder, A Czibere, U Platzbecker, G Bug, L Uharek, T Luft, A Giagounidis in Leukemia (2013)

  14. No Access

    Article

    Survival, prognostic factors and rates of leukemic transformation in 381 untreated patients with MDS and del(5q): A multicenter study

    Myelodysplastic syndromes (MDS) with del(5q) are considered to have a benign course of the disease. In order to address the issue of the propensity of those patients to progress to acute myeloid leukemia (AML)...

    U Germing, M Lauseker, B Hildebrandt, A Symeonidis, J Cermak, P Fenaux in Leukemia (2012)

  15. No Access

    Article

    Long-term transfusion independence in del(5q) MDS patients who discontinue lenalidomide

    A A N Giagounidis, A Kulasekararaj, U Germing, R Radkowski, S Haase, P Petersen in Leukemia (2012)

  16. Article

    Open Access

    Azacitidine for treatment of imminent relapse in MDS or AML patients after allogeneic HSCT: results of the RELAZA trial

    This study evaluated azacitidine as treatment of minimal residual disease (MRD) determined by a sensitive donor chimerism analysis of CD34+ blood cells to pre-empt relapse in patients with CD34+ myelodysplastic s...

    U Platzbecker, M Wermke, J Radke, U Oelschlaegel, F Seltmann, A Kiani, I-M Klut in Leukemia (2012)

  17. No Access

    Article

    Haploidentical bone marrow transplantation with post-grafting cyclophosphamide: multicenter experience with an alternative salvage strategy

    S Tuve, J Gayoso, C Scheid, J Radke, A Kiani, D Serrano, U Platzbecker in Leukemia (2011)

  18. No Access

    Article

    Successful treatment of molecular relapse in NPM1-positive AML using 5-azacytidine

    M Wermke, C Thiede, A Kiani, G Ehninger, M Bornhäuser, U Platzbecker in Leukemia (2010)

  19. No Access

    Article

    Induction of Toll-like receptor 2 and 4 expression on CD4+ and CD8+ T cells in G-CSF-mobilized unrelated peripheral blood stem cell grafts during leukapheresis: impact on patient outcome

    U Platzbecker, J Stoehlmacher, C Pabst, E Goekkurt, U Oelschlägel in Leukemia (2008)

  20. No Access

    Article

    Lenalidomide as induction therapy before allogeneic stem cell transplantation in a patient with proliferative CMML-2 and del(5q) not involving the EGR1 locus

    U Platzbecker, B Mohr, M von Bonin, M Binder, J Schetelig, G Ehninger in Leukemia (2007)

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