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Article
Open AccessInsufflation pressure above 25 mm Hg confers no additional benefit over lower pressure insufflation during posterior retroperitoneoscopic adrenalectomy: a retrospective multi-centre propensity score-matched analysis
Insufflation pressures of or in excess of 25 mm Hg CO2 are routinely used during posterior retroperitoneoscopic adrenalectomy (PRA) in most centres. A critical analysis of the surgical literature provides limited...
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Chapter
Gastrointestinale Stromatumoren und Sarkome
Sarkome sind seltene Tumoren, die weniger als 1 % der neudiagnostizierten Malignome des Erwachsenen jährlich ausmachen. Weichteilsarkome können in jedem Teil des Körpers vorkommen; in abnehmender Inz...
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Chapter
Pankreas
Das Pankreas wurde erstmals in Schriften von Eristratos (304–250 v. Chr.) erwähnt; erst im 18. Jahrhundert wurde das Organ anatomisch genau beschrieben. Obwohl die Chirurgie des Pankreas sich in der ...
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Chapter
Individualisierte Pankreaschirurgie
Dieses Kapitel enthält eine Beschreibung der technischen Schritte von duodenumerhaltender Pankreaskopfresektion, Papillenresektion, Operation nach Whipple sowie zentraler und distaler Pankreasresektion, die in...
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Article
The Relative Role of Bile Bacterial Isolation on Outcome in Stent-Bearing Patients Undergoing Pancreatoduodenectomy
Biliary stenting leads to antimicrobial-resistant (AMR) microorganism retrievement in bile cultures. However, the impact of intraoperative bile colonizations on post-pancreaticoduodenectomy complications remai...
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Article
Tumor budding as a prognostic factor in pancreatic ductal adenocarcinoma
In this retrospective study, we analyzed the association between tumor budding and perineural invasion as well as their prognostic role in pancreatic ductal adenocarcinoma. A total of N = 119 patients resected fo...
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Article
Long-term outcome of surgical resection in patients with gastroenteropancreatic neuroendocrine neoplasia: results from a German nation-wide multi-centric registry
Neuroendocrine neoplasia (NEN) are rare and heterogenous tumours. Few data exist on the impact of surgical therapy.
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Article
Open AccessNeoadjuvant chemotherapy with gemcitabine plus cisplatin followed by radical liver resection versus immediate radical liver resection alone with or without adjuvant chemotherapy in incidentally detected gallbladder carcinoma after simple cholecystectomy or in front of radical resection of BTC (ICC/ECC) – a phase III study of the German registry of incidental gallbladder carcinoma platform (GR)– the AIO/ CALGP/ ACO- GAIN-trial –
Currently, complete surgical resection represents the only potentially curative treatment option for Biliary Tract Cancer (BTC) including Gallbladder Cancer (GBC). Even after curative resection, 5-year OS is o...
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Living Reference Work Entry In depth
Minimalinvasive Verfahren in der onkologischen Viszeralchirurgie: Hepatobiliär und Pankreas
Der Anteil an laparoskopischen Verfahren in der Leberchirurgie nahm in den letzten Jahren kontinuierlich zu. Für die laparoskopische Resektion eignen sich insbesondere Befunde in den Segmenten II und III sowie...
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Article
Indications for resection and perioperative outcomes of surgery for pancreatic neuroendocrine neoplasms in Germany: an analysis of the prospective DGAV StuDoQ|Pancreas registry
Pancreatic neuroendocrine neoplasms (pNENs) are rare, and their surgical management is complex. This study evaluated the current practice of pNEN surgery across Germany, including its adherence with guidelines...
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Article
Deep transfer learning methods for colon cancer classification in confocal laser microscopy images
The gold standard for colorectal cancer metastases detection in the peritoneum is histological evaluation of a removed tissue sample. For feedback during interventions, real-time in vivo imaging with confocal ...
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Article
Laparoscopic surgery for rectal cancer reveals comparable oncological outcome even in context of worse short-term results—long-term analysis of nearly 500 patients from two high-volume centers
Large randomized controlled trials have investigated the oncological value of the laparoscopic approach to colorectal cancer. Mainly, non-inferiority for the laparoscopic approach regarding long-term survival ...
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Article
Application-based management of perioperative anticoagulant therapy: description of POPACTApp
Perioperative management of oral anticoagulation (OAC) is a constant challenge in interventional and surgical procedures. When deciding to discontinue OAC, the risk of thromboembolic events must be balanced ag...
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Article
Confocal laser microscopy as novel approach for real-time and in-vivo tissue examination during minimal-invasive surgery in colon cancer
Histological analysis of surgical specimen is the gold standard for cancer classification. In particular, frozen histological diagnosis of vague peritoneal spots or uncertain excision of tumors plays a crucial...
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Chapter
Palliative Chirurgie des Pankreaskarzinoms
Das Pankreaskarzinom ist durch seine hohe Aggressivität und schlechte Prognose gekennzeichnet. Trotz kurativer Intention bleiben die meisten Resektionen palliativer Natur. Auf der Grundlage der präoperativen B...
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Chapter and Conference Paper
Feasibility of Colon Cancer Detection in Confocal Laser Microscopy Images Using Convolution Neural Networks
Histological evaluation of tissue samples is a typical approach to identify colorectal cancer metastases in the peritoneum. For immediate assessment, reliable and real-time in-vivo imaging would be required. F...
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Article
Implementation of Current ENETS Guidelines for Surgery of Small (≤2 cm) Pancreatic Neuroendocrine Neoplasms in the German Surgical Community: An Analysis of the Prospective DGAV StuDoQ|Pancreas Registry
ENETS guidelines recommend parenchyma-sparing procedures without formal lymphadenectomy, ideally with a minimally invasive laparoscopic approach for sporadic small pNENs (≤2 cm). Non-functioning (NF) small pNE...
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Article
Analysis of laparoscopic laser liver resection in standardized porcine model
Hepatocellular carcinoma is a highly prevalent and lethal primary neoplasia of the liver and metastases of other malignancies affect most frequently the liver. Minimally invasive surgical approach for liver re...
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Article
Gender-related differences in patients with colon cancer resection
In recent years, studies have revealed gender-related differences in many fields of medicine. Data on oncologic surgical patients show different pathologic, perioperative, and long-term outcomes between men an...
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Article
Conception of the Lübeck Toolbox curriculum for basic minimally invasive surgery skills
Difficulties at the beginning of the learning curve in minimally invasive surgery (MIS) can well be overcome by simulation outside the operating room. Despite a great number of available devices, standardized,...
