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Living Reference Work Entry In depth
Infektionen des zentralen Nervensystems
Infektionserkrankungen des zentralen Nervensystems (ZNS) werden von unterschiedlichen bakteriellen, viralen, parasitären Erregern und Pilzen hervorgerufen. Sowohl das Erregerspektrum als auch die Symptomatik i...
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Article
Open AccessGerman cohort of HCV mono-infected and HCV/HIV co-infected patients reveals relative under-treatment of co-infected patients
Current German and European HIV guidelines recommend early evaluation of HCV treatment in all HIV/HCV co-infected patients. However, there are still considerable barriers to initiate HCV therapy in everyday cl...
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Article
Open AccessSafety and efficacy of protease inhibitor based combination therapy in a single-center “real-life” cohort of 110 patients with chronic hepatitis C genotype 1 infection
The combination of boceprevir or telaprevir with peginterferon-alfa and ribavirin for the treatment of patients infected with HCV genotype 1 has led to significantly increased rates of sustained virological re...
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Article
Characterization of Enterobacter cloacae Pneumonia: A Single-Center Retrospective Analysis
Enterobacter cloacae (E. cloacae) is a Gram-negative rod commonly found on intensive care units (ICU) causing severe infections with high mortality. Specific characteristics of E. cloa...
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Article
PKCμ prevents CD95-mediated apoptosis and enhances proliferation in pancreatic tumour cells
Loss of growth control and a marked resistance to apoptosis are considered major mechanisms driving tumour progression. Protein kinases C (PKC) have been shown to be important in the regulation of proliferatio...