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Article
Open AccessEffects of resveratrol on bone health in type 2 diabetic patients. A double-blind randomized-controlled trial
Patients with type 2 diabetes (T2DM) are at increased fracture risk. Resveratrol has shown beneficial effects on bone health in few studies. The aim of this trial was to investigate the effects of resveratrol ...
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Article
Open AccessChanges in the gut microbiota composition during pregnancy in patients with gestational diabetes mellitus (GDM)
Gestational diabetes mellitus (GDM), a common pregnancy complication, is associated with an increased risk of maternal/perinatal outcomes. We performed a prospective observational explorative study in 41 GDM p...
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Article
Prevalence of obesity in Italian adolescents: does the use of different growth charts make the difference?
Since populations are becoming increasingly multi-ethnic, the use of local or international charts is a matter of debate. This study aimed to evaluate how the choice of cut-off thresholds affected prevalence o...
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Article
Open AccessImpact of sirtuin-1 expression on H3K56 acetylation and oxidative stress: a double-blind randomized controlled trial with resveratrol supplementation
Sirtuin-1 (SIRT-1) down-regulation in type 2 diabetes mellitus (T2DM) has been associated with epigenetic markers of oxidative stress. We herein aim to evaluate whether an increase in SIRT-1 expression affects...
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Article
Open AccessEffects of meal timing on changes in circulating epinephrine, norepinephrine, and acylated ghrelin concentrations: a pilot study
Timing of food intake impacts on metabolic diseases. Few data are available about post-meal changes in epinephrine (E), norepinephrine (NE), and acylated ghrelin (AG) at different times of the day.
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Article
Open AccessPredictive role of the Mediterranean diet on mortality in individuals at low cardiovascular risk: a 12-year follow-up population-based cohort study
Adherence to the Mediterranean diet reduces the risk of all-cause and cardiovascular (CV) mortality and the incidence of CV events. However, most previous studies were performed in high-risk individuals. Our o...
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Article
Open AccessDietary flavonoid intake and cardiovascular risk: a population-based cohort study
The cardio-protective effects of flavonoids are still controversial; many studies referred to the benefits of specific foods, such as soy, cocoa, tea. A population-based cohort of middle-aged adults, coming fr...
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Article
Open AccessUniversity courses, eating problems and muscle dysmorphia: are there any associations?
Orthorexia and muscle dysmorphia are disorders affecting above all young adults whose prevalence and social impact are still unclear. We aimed to evaluate the prevalence of the traits of orthorexia and muscle ...
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Article
Open AccessResveratrol: a supplementation for men or for mice?
Resveratrol is a polyphenolic compound found in several plants. In the last decades, the interest in this compound has enormously increased after benefits on metabolism and increased lifespan of various organi...
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Article
Overlap Syndromes of Autoimmune Hepatitis: An Open Question
The headword “overlap syndromes” of liver diseases includes the coexistence of autoimmune hepatitis, primary biliary cirrhosis, and primary sclerosing cholangitis. These syndromes often represent a diagnostic ...
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Article
Using Data Mining Techniques in Monitoring Diabetes Care. The Simpler the Better?
We aim at evaluating how data-mining statistical techniques can be applied on medical records and administrative data of diabetes and how they differ in terms of capabilities of predicting outcomes (e.g. death...
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Article
Type 1 autoimmune hepatitis and adipokines: new markers for activity and disease progression?
Cytokines may play an important role as inflammatory factors in liver diseases. There is some evidence suggesting a link between adiponectin–biliary function and liver disease. The aim of this study was to cla...
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Article
Open AccessImplementing hospital guidelines improves warfarin use in non-valvular atrial fibrillation: a before-after study
The use of oral anticoagulant therapy (OAT) to prevent non-valvular atrial fibrillation (NVAF) related-strokes is often sub-optimal. We aimed to evaluate whether implementing guidelines on antithrombotic thera...
