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Article
Heavy alcohol consumption in children and adolescents: characteristics and gender differences
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Article
The role of milrinone in children with cardiovascular compromise: review of the literature
GRUNDLAGEN: Kardiovaskuläre Funktionsstörungen treten bei Kindern gehäuft nach herzchirurgischen Operationen unter Verwendung der Herz-Lungen-Maschine und im Rahmen eines Schockgeschehens auf. METHODIK: System...
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Article
The role of vasopressin and terlipressin in catecholamine-resistant shock and cardio-circulatory arrest in children: Review of the literature
GRUNDLAGEN: Der katecholamin-refraktäre Schock und das Herz-Kreislaufversagen im Kindesalter sind mit einer hohen Morbidität und Mortalität assoziiert. In den letzten Jahren wird zunehmend Vasopressin und Terl...
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Article
Open AccessDifferential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages
Investigations on pulmonary macrophages (MΦ) mostly focus on alveolar MΦ (AM) as a well-defined cell population. Characteristics of MΦ in the interstitium, referred to as lung interstitial MΦ (IM), are rather ...
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Article
Smoking and smoking cessation during pregnancy
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Article
Mechanisms of disease/hypothesis: Neurogenic left ventricular dysfunction and neurogenic pulmonary oedema
GRUNDLAGEN: Das Auftreten kardiovaskulärer Funktionsstörungen kann durch eine akute Störung des zentralen autonomen Nervensystems verursacht werden. Die Inselregion, der laterale Hypothalamus sowie der Hirnsta...
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Article
Iatrogenic ventricular tachycardia
Cardiac arrhythmias may complicate the clinical course in infants and children following cardiac surgery. Here, we report on a 6-week-old neonate who developed life-threatening ventricular tachycardia with car...
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Article
Comment on “Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with haematological malignancies” by Vandijck et al.
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Article
Evidence-based medicine in neonatology: time to re-think
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Article
Open AccessSurfactant replacement and open lung concept – Comparison of two treatment strategies in an experimental model of neonatal ARDS
Several concepts of treatment in neonatal ARDS have been proposed in the last years. The present study compared the effects of open lung concept positive pressure ventilation (PPVOLC) with a conventional ventilat...
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Article
Pain management in neonates for painful procedures
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Article
Arginine-vasopressin as a rescue therapy in children and neonates for catecholamine-resistant shock
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Article
Early fatal course in siblings with CDG-Ia (caused by two novel mutations in the PMM2 gene): clinical, molecular and autopsy findings
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Article
Sedation and analgesia for brief diagnostic and therapeutic procedures in children
The number of diagnostic and therapeutic procedures done outside of the operating room and the intensive care unit has increased substantially in recent years. In parallel, the management of acute pain and anx...
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Article
Simultaneous tuberculous meningoencephalitis in two siblings
Aufgrund der hohen Morbidität und Mortalität erfordert die tuberkulöse Meningoencephalitis (TBM) eine rasche Diagnose und einen sofortigen Beginn einer tuberkulostatischen Therapie. Durch die BCG-Impfung konnt...
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Article
Open AccessArginine-vasopressin in catecholamine-refractory septic versus non-septic shock in extremely low birth weight infants with acute renal injury
The aim of this study was to assess the efficacy of arginine-vasopressin (AVP) as a rescue therapy in catecholamine-refractory septic and non-septic shock in extremely low birth weight (ELBW) infants with acut...
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Article
Fulminant hepatic failure in a newborn with herpes simplex virus 2 infection
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Article
Assessing the risk of mortality in paediatric cancer patients admitted to the paediatric intensive care unit: a novel risk score?
Intensive front-line protocols have improved survival in children with malignancies; however, intensive multimodal therapy of paediatric malignancies can be associated with a significant risk of serious advers...
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Article
Synthetic and natural surfactant differentially modulate inflammation after meconium aspiration
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Article
Gamma-hydroxy butyric acid: Neurotransmitter, sedative and party drug
Gamma-hydroxybutyric acid (GHB) as a natural component of the mammalian brain was first introduced in clinical anaesthesic practice more than 40 years ago. The drug was nearly forced from clinical practice bec...
