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  1. No Access

    Article

    Exploration into the Mechanism of Yiyi Baijiang Decoction Attenuating Chronic Pelvic Inflammation Based on Network Pharmacology and Experimental Verification

    Patients with chronic pelvic inflammation (CPI) experience irregular menstrual, ectopic pregnancy, and infertility. Yiyi Baijiang Decoction attenuates CPI in patients with uncovered mechanisms. CPI therapeutic...

    Yanting Wei, Hongning Su, Jiajia Li, Wenli Zheng, Lili Li… in Biochemical Genetics (2024)

  2. No Access

    Article

    Bioinformatic Analysis of the Significance of the KIR2DL4 Gene in Recurrent Implantation Failure

    Related studies have pointed out that Killer immunoglobulin-like receptor 2DL4 (KIR2DL4) was associated with vascular remodeling in early pregnancy, and it might play an important role in immunity. In this stu...

    **n-**an Zhang, Zhi-Chao Zhang, Yu-Shan Liu, Li Zhou, Yu-Qin Hu… in Biochemical Genetics (2024)

  3. No Access

    Article

    Identification and Characterization of LBD Gene Family in Pseudoroegneria libanotica Reveals Functions of PseLBD1 and PseLBD12 in Response to Abiotic Stress

    The lateral organ boundaries domain (LBD) plays a vital role as a transcriptional coactivator within plants, serving as an indispensable function in growth, development, and stress response. In a previous study, ...

    Xunzhe Yang, **ang Li, **a Wang, Chen Chen, Dandan Wu, Yiran Cheng… in Biochemical Genetics (2024)

  4. No Access

    Article

    Genetic Variability of CYP4F2, CYP2D6, CYP2E1, and ACE in the Chinese Yi Population

    Genetic polymorphisms of very important pharmacogenes (VIP) are a significant factor contributing to inter-individual variability in drug therapy. The purpose of this study was to identify significantly differ...

    **** Guo, Wenqian Zhou, **aoya Ma, Yujie Li, Huan Zhang, Jie Wei… in Biochemical Genetics (2024)

  5. No Access

    Article

    Exosome-Mediated Communication in Thyroid Cancer: Implications for Prognosis and Therapeutic Targets

    Thyroid cancer (THCA) is one of the most common malignancies of the endocrine system. Exosomes have significant value in performing molecular treatments, evaluating the diagnosis and determining tumor prognosi...

    Yiwei Wang, Qiang Li, **nrui Yang, Hanyu Guo, Tian Ren… in Biochemical Genetics (2024)

  6. No Access

    Article

    Transcriptomic Analysis Under Drought and Salt Stress Provides Insight into Genes Putatively Involved in Ginsenoside Biosynthesis in Panax japonicus Meyer

    Panax japonicus Meyer, a perennial herb of the dicotyledonaceae family Araliaceae, is a rare folk traditional Chinese medicine, known as “the king of herbal medicine” in China. To understand the genes involved in...

    Jiangbo Zhou, **g Li, E. Liang, Minjie Qi, Yuanshe Huang… in Biochemical Genetics (2024)

  7. No Access

    Article

    Ginsenoside Rb2 Inhibits the Pyroptosis in Myocardial Ischemia Progression Through Regulating the SIRT1 Mediated Deacetylation of ASC

    Myocardial ischemic (MI) injury is a common cardiovascular disease, and the potential therapeutic effects of ginsenoside Rb2 (Rb2) have been lately the focus of interest. Therefore, this study aimed to investi...

    Yuning Li, Wenhua Zhang, Yamin Cai, Dong Yang in Biochemical Genetics (2024)

  8. No Access

    Article

    Sulfur Dioxide Alleviates Organ Damage and Inflammatory Response in Cecal Ligation and Puncture-Induced Sepsis Rat

    The study aimed to elucidate the mechanisms by which sulfur dioxide (SO2) alleviates organ damage during sepsis using RNA-Seq technology. A cecal ligation and puncture (CLP) sepsis model was established in rats, ...

    Bin Li, Ke** Jiao, Binsheng Wang, Hongzhong Gou, Chen Chai… in Molecular Biotechnology (2024)

  9. No Access

    Article

    Construction of a Membrane Yeast Two-Hybrid Library and Screening of MsPYR1-Like Interacting Proteins in Malus sieversii

    To investigate the biological effects of the ABA receptor pyrabactin resistance 1-like (PYR1-like) in Malus sieversii seeds, the proteins interacting with MsPYR1-like were screened by the membrane yeast two-hybri...

    Zhen Fang, Kai Zhang, **g Li, Juan Ma, Chunxiu Ye in Molecular Biotechnology (2024)

  10. Article

    Correction to: Construction of a New Immune-Related Competing Endogenous RNA Network with Prognostic Value in Lung Adenocarcinoma

    Li Liu, **g Li, Chunhui Fan, Mingyi Wen, Cunqi Li, Wen Sun… in Molecular Biotechnology (2024)

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  11. No Access

    Article

    Circular RNA circ_0101675 Promotes NSCLC Cell Proliferation, Migration, Invasion, Angiogenesis and Immune Evasion by Sponging miR-607/PDL1 Axis

    Non-small cell lung cancer (NSCLC) is one of the most common and fatal cancers in the world. Circular RNA (circRNA) can broadly participate in the initiation and progression of the NSCLC. However, the regulato...

    Wei Lu, Liang Li, Li Li, Nanbian Guo, **miao Ma in Biochemical Genetics (2024)

  12. No Access

    Article

    Multi-dimensional Insight into the Coexistence of Pathogenic Genes for ADAR1 and TSC2: Careful Consideration is Essential for Interpretation of ADAR1 Variants

    Aicardi–Goutières syndrome 6 (AGS6) is a serious auto-immunization-associated acute neurologic decompensation. AGS6 manifests as acute onset of severe generalized dystonia of limbs and developmental regression...

    **angyu Liu, Meifang Lei, Yan Xue, Hong Li, **g Yin, Dong Li… in Biochemical Genetics (2024)

  13. No Access

    Article

    Promoter Mutation of the bZIP Transcription Factor BdABF Accelerates Flowering in Brachypodium distachyon

    Flowering time plays an important role in crop regional adaptation, yield and reproductive success. ABRE BINDING FACTORs (ABFs) are bZIP transcription factors that participate in various plant biological proce...

    B. J. Han, Z. J. Liu, W. M. Bai, F. T. Sun, Y. F. Niu, T. Y. Song… in Molecular Biology (2024)

  14. No Access

    Article

    Cancer-Associated Fibroblasts Boost Tumorigenesis of Clear Cell Renal Cell Carcinoma via Exosome-Mediated Paracrine SNHG1

    Despite the dominant roles of cancer-associated fibroblasts (CAFs) have attached much attention in tumorigenesis, the CAFs-derived molecular determinants that regulate renal cell carcinoma (RCC) development re...

    Pei Tian, **xing Wei, **g Li, Junkai Ren, Chaohong He in Biochemical Genetics (2024)

  15. No Access

    Article

    circ_0000337 Promotes the Progression of Cervical Cancer by miR-155-5p/RAB3B Axis

    Current study aims to investigate the biological function of circular RNA (circRNA, circ_0000337) in cervical cancer (CC). Bioinformatic analyses were used to predict targets for circ_0000337 and miR-155-5p, a...

    Jiqin Xu, Bai Xue, Min Gong, Ling Ling, Sipei Nie, Fujun Li… in Biochemical Genetics (2024)

  16. No Access

    Article

    Circ_0005785 Silencing Constrains the Functional Properties of Colorectal Cancer Cells Depending on miR-7-5p/DNMT3A Axis

    Circular RNAs (circRNAs) closely related to the progression of colorectal cancer (CRC). Nevertheless, the study of circ_0005785 in CRC has not been reported. In this test, we aimed to investigate the mechanisms o...

    Zhu Li, Gangling Tong, **aodan Peng, Shubin Wang in Biochemical Genetics (2024)

  17. No Access

    Article

    Pathogenicity of Congenital Adrenal Hyperplasia Induced by the p.P377L Mutation of CYP11B1

    CYP11B1 encodes an 11β-hydroxylase that is involved in the catalysis of adrenal glucocorticoids and the production of cortisol. Mutations in CYP11B1 can result in congenital adrenal hyperplasia. We discovered a p...

    Guoying Ma, Reziwanguli Wusiman, Suli Li, Fuhui Ma, Yanying Guo in Biochemical Genetics (2024)

  18. No Access

    Article

    miR-29a-SIRT1-Wnt/β-Catenin Axis Regulates Tumor Progression and Survival in Hepatocellular Carcinoma

    Sirtuin 1 (SIRT1) participates in the initiation and evolution of hepatocellular carcinoma (HCC). However, the specific mechanism of SIRT1 in HCC remains unclear. The mRNA expression of miR-29a in HCC were ide...

    Liqiang Qian, Yanjun Zhang, Gang Wang, Bin Li, Hemei Zhou, Jie Qiu… in Biochemical Genetics (2024)

  19. No Access

    Article

    Exploring the Targets and Molecular Mechanisms of Curcumin for the Treatment of Bladder Cancer Based on Network Pharmacology, Molecular Docking and Molecular Dynamics

    Curcumin, a phenolic compound derived from turmeric, has demonstrated anti-tumor properties in preclinical models of various cancers. However, the exact mechanism of curcumin in treating bladder cancer remains...

    Jun Li, Shujie Feng, **ong Wang, Bingmei Zhang, Qingmin He in Molecular Biotechnology (2024)

  20. No Access

    Article

    Application of Cadherin cRNA Probes in Brains of Alzheimer’s Disease Mouse Model

    The cadherin superfamily molecules, functioning as cell adhesion molecules, are recognized to play roles in both physiological and pathological processes. The cadherin-based adherent junction (CAJ) is believed...

    H. Zhou, S. J. Du, F. Gendi, H. Y. Li, J. Fu, C. Chang in Molecular Biology (2024)

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