115 Result(s)

Article

Population genetic analysis of the Plasmodium falciparum erythrocyte binding antigen-175 (EBA-175) gene in Equatorial Guinea

Plasmodium falciparum erythrocyte binding antigen-175 (PfEBA-175) is a candidate antigen for a blood-stage malaria vaccine, while various polymorphisms and dimorphism have prevented to development of effective va...

Pei-Kui Yang, Xue-Yan Liang, Min Lin, Jiang-Tao Chen, Hui-Ying Huang… in Malaria Journal (2021)

Article

Urinary small extracellular vesicles derived CCL21 mRNA as biomarker linked with pathogenesis for diabetic nephropathy

Diabetic nephropathy (DN) is a leading cause of renal failure, whereas the effective and early diagnostic biomarkers are still lacking.

Ye Feng, **n Zhong, Hai-Feng Ni, Cui Wang… in Journal of Translational Medicine (2021)

Article

Plant developmental stage drives the differentiation in ecological role of the maize microbiome

Plants live with diverse microbial communities which profoundly affect multiple facets of host performance, but if and how host development impacts the assembly, functions and microbial interactions of crop mi...

Chao **ong, Brajesh K. Singh, Ji-Zheng He, Yan-Lai Han, Pei-Pei Li… in Microbiome (2021)

Article

A urine extracellular vesicle circRNA classifier for detection of high-grade prostate cancer in patients with prostate-specific antigen 2–10 ng/mL at initial biopsy

The aim of this study was to identify a urine extracellular vesicle circular RNA (circRNA) classifier that could detect high-grade prostate cancer (PCa) of Grade Group (GG) 2 or greater. For this purpose, we u...

Ya-Di He, Wen Tao, Tao He, Bang-Yu Wang, **u-Mei Tang, Liang-Ming Zhang… in Molecular Cancer (2021)

Article

A positive feedback loop between Periostin and TGFβ1 induces and maintains the stemness of hepatocellular carcinoma cells via AP-2α activation

Liver cancer stem cells (LCSCs) play key roles in the metastasis, recurrence, and chemotherapeutic resistance of hepatocellular carcinoma (HCC). Our previous research showed that the POSTN gene is closely related...

Gang Chen, Yi Wang, **n Zhao, **ao-zai **e… in Journal of Experimental & Clinical Cancer … (2021)

Article

Dissecting the multi-omics atlas of the exosomes released by human lung adenocarcinoma stem-like cells

Lung adenocarcinoma is heterogeneous and hierarchically organized, with a subpopulation of stem-like cells (CSCs) that reside at the apex of the hierarchy, in which exosomes act as important mediators by trans...

Hai-Tao Luo, Yuan-Yuan Zheng, Jun Tang, Li-Juan Shao, Yi-Heng Mao… in npj Genomic Medicine (2021)

Article

Correction to: Akt/FoxM1 signaling pathway-mediated upregulation of MYBL2 promotes progression of human glioma

Xue Zhang, Qiao-Li LV, Yuan-Tao Huang… in Journal of Experimental & Clinical Cancer … (2021)

Article

Epidemiology, species distribution, and outcome of nosocomial Candida spp. bloodstream infection in Shanghai: an 11-year retrospective analysis in a tertiary care hospital

The incidence of Candida bloodstream infections (BSIs), has increased over time. In this study, we aimed to describe the current epidemiology of Candida BSI in a large tertiary care hospital in Shanghai and to de...

Yan-Jun Zheng, Ting **e, Lin Wu… in Annals of Clinical Microbiology and Antimi… (2021)

Article

MiR-27a-3p promotes the osteogenic differentiation by activating CRY2/ERK1/2 axis

Osteoporosis seriously disturbs the life of people. Meanwhile, inhibition or weakening of osteogenic differentiation is one of the important factors in the pathogenesis of osteoporosis. It was reported that mi...

Li-Rong Ren, Ru-Bin Yao, Shi-Yong Wang, **ang-Dong Gong, Ji-Tao Xu… in Molecular Medicine (2021)

Article

Genetic diversity and natural selection on the thrombospondin-related adhesive protein (TRAP) gene of Plasmodium falciparum on Bioko Island, Equatorial Guinea and global comparative analysis

Thrombospondin-related adhesive protein (TRAP) is a transmembrane protein that plays a crucial role during the invasion of Plasmodium falciparum into liver cells. As a potential malaria vaccine candidate, the gen...

Li-Yun Lin, Hui-Ying Huang, Xue-Yan Liang, Dong-De **e, Jiang-Tao Chen… in Malaria Journal (2021)

Article

Systematic identification of key functional modules and genes in esophageal cancer

Esophageal cancer is associated with high incidence and mortality worldwide. Differential expression genes (DEGs) and weighted gene co-expression network analysis (WGCNA) are important methods to screen the co...

Rui Wu, Hao Zhuang, Yu-Kun Mei, **-Yu Sun, Tao Dong… in Cancer Cell International (2021)

Article

Gut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disorder with no absolute cure. The evidence of the involvement of gut microbiota in PD pathogenesis suggests the need to identify certain molecule(s) derived fr...

Yan-fang Hou, Chang Shan, Si-yue Zhuang, Qian-qian Zhuang, Arijit Ghosh… in Microbiome (2021)

Article

Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells

Anterior gradient-2 (AGR2) is a proto-oncogene involved in tumorigenesis and cancer progression. AGR2, predominantly localized in the endoplasmic reticulum (ER), is also a secreted protein detected in the extr...

**an Hong, Zhi-Xuan Li, Jie Hou, Hui-Yu Zhang, Chun-Yan Zhang, Jian Zhang… in BMC Cancer (2021)

Article

Correction to: The chemodiversity of paddy soil dissolved organic matter correlates with microbial community at continental scales

An amendment to this paper has been published and can be accessed via the original article.

Hong-Yi Li, Hang Wang, Hai-Tao Wang, Pei-Yong **n, **n-Hua Xu, Yun Ma… in Microbiome (2020)

Article

Characterization of Neoschoengastia gallinarum from subtropical China by rDNA and identification of two genotypes based on mitochondrial cox1

Genetic variations in the 18S ribosomal DNA (18S), 28S ribosomal DNA (28S), second internal transcribed spacer of ribosomal DNA (ITS2), and mitochondrial cytochrome c oxidase subunit 1 (cox1) of Neoschoengastia g...

Qiang Zhou, Zhan-**n Wang, Jia-Meng Tao, Jian-** Qin… in Parasitology Research (2020)

Article

Brief report of the first cured 2019-nCoV pneumonia patient in West China Hospital

En-Qiang Chen, Li-Chun Wang, Guang-Min Tang… in European Journal of Clinical Microbiology … (2020)

Article

Genetic polymorphism of Plasmodium falciparum circumsporozoite protein on Bioko Island, Equatorial Guinea and global comparative analysis

Plasmodium falciparum circumsporozoite protein (PfCSP) is a potential malaria vaccine candidate, but various polymorphisms of the pfcsp gene among global P. falciparum population become the major barrier to the e...

Hui-Ying Huang, Xue-Yan Liang, Li-Yun Lin, Jiang-Tao Chen… in Malaria Journal (2020)

Article

Clinical characteristics of 34 COVID-19 patients admitted to intensive care unit in Hangzhou, China

This study summarizes and compares clinical and laboratory characteristics of 34 patients admitted to the intensive care unit (ICU) for complications from coronavirus disease 2019 (COVID-19) at the First Affil...

Yi Zheng, Li-jun Sun, Mi Xu, Jian Pan… in Journal of Zhejiang University-SCIENCE B (2020)

Article

Dissection of the cecal microbial community in chickens after Eimeria tenella infection

Eimeria spp. are responsible for chicken coccidiosis which is the most important enteric protozoan disease resulting in tremendous economic losses in the poultry industry. Understanding the interaction between th...

Hong-Liang Chen, **n-Yu Zhao, Guang-Xun Zhao, Hai-Bin Huang… in Parasites & Vectors (2020)

Article

The Evi5 oncogene promotes laryngeal cancer cells proliferation by stabilizing c-Myc protein

The Ecotropic viral integration site 5 (Evi5) is recognized as a potential oncogene and a cell cycle regulator. Evi5 regulates the abundance of Emi1, an inhibitor of the anaphase-promoting complex/cyclosome, t...

Cheng-Gang Mao, **ao-Chun Zhou, Yi-Dao Jiang, Li-Jia Wan… in Cancer Cell International (2020)