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Publisher Correction: A naturally occurring antiviral ribonucleotide encoded by the human genome
Change history: In the HTML version of this Letter, Extended Data Fig. 4 incorrectly corresponded to Fig. 4 (the PDF version of the figure was correct). This has been corrected online.
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The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses
Here we describe the complete genome of a new ebolavirus, Bombali virus (BOMV) detected in free-tailed bats in Sierra Leone (little free-tailed (Chaerephon pumilus) and Angolan free-tailed (Mops condylurus)). The...
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Taxonomy of the order Mononegavirales: update 2018
In 2018, the order Mononegavirales was expanded by inclusion of 1 new genus and 12 novel species. This article presents the updated taxonomy of the order Mononegavirales as now accepted by the International Commi...
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A naturally occurring antiviral ribonucleotide encoded by the human genome
Viral infections continue to represent major challenges to public health, and an enhanced mechanistic understanding of the processes that contribute to viral life cycles is necessary for the development of new...
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Article
Taxonomy of the order Mononegavirales: update 2017
In 2017, the order Mononegavirales was expanded by the inclusion of a total of 69 novel species. Five new rhabdovirus genera and one new nyamivirus genus were established to harbor 41 of these species, whereas th...
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How to turn competitors into collaborators
Erica Ollmann Saphire and colleagues share lessons in finding treatments fast from the work on Ebola by the Viral Hemorrhagic Fever Immunotherapeutic Consortium.
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Taxonomy of the order Mononegavirales: update 2016
In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae and Sunviridae), the elevation of the paramyxoviral subfamily Pneumovirinae to family status (Pneumoviridae),...
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Use of functional gene expression and respirometry to study wastewater nitrification activity after exposure to low doses of copper
Autotrophic nitrification in biological nitrogen removal systems has been shown to be sensitive to the presence of heavy metals in wastewater treatment plants. Using transcriptase-quantitative polymerase chain...
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Open AccessBispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses
Filoviruses (Ebola and Marburg) cause severe hemorrhagic fever. There are five species of ebolavirus; among these, the Ebola (Zaire) and Sudan viruses (EBOV and SUDV, respectively) are highly pathogenic and ha...
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Factors controlling nitrous oxide emissions from a full-scale activated sludge system in the tropics
Despite interest in characterizing nitrous oxide (N2O) emissions from wastewater treatment plants (WWTPs) in several parts of the globe, there are few studies in tropical zones. This study focus on the contributi...
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Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA
Specific alterations (mutations, deletions, insertions) of virus genomes are crucial for the functional characterization of their regulatory elements and their expression products, as well as a prerequisite fo...
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Discussions and decisions of the 2012–2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012–June 2013
The International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group prepares proposals on the classification and nomenclature of filoviruses to reflect current knowledge or to correct disagreements...
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Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae
The International Committee on Taxonomy of Viruses (ICTV) organizes the classification of viruses into taxa, but is not responsible for the nomenclature for taxa members. International experts groups, such as ...
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Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae
The task of international expert groups is to recommend the classification and naming of viruses. The International Committee on Taxonomy of Viruses Filoviridae Study Group and other experts have recently establi...
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A shared structural solution for neutralizing ebolaviruses
The surface glycoprotein of the distinct ebolavirus responsible for the largest outbreak yet described (Sudan Gulu) has been crystallized in complex with a novel, neutralizing antibody. The crystal structure a...
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Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
The extraordinary virulence of the Ebola and Marburg filoviruses has spurred intensive research into the molecular mechanisms by which they multiply and cause disease. Carette et al. use a genome-wide genetic scr...
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Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection
The extraordinary virulence of the Ebola and Marburg filoviruses has spurred intensive research into the molecular mechanisms by which they multiply and cause disease. Carette et al. use a genome-wide genetic scr...
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Open AccessStrategies of Nitrosomonas europaea 19718 to counter low dissolved oxygen and high nitrite concentrations
Nitrosomonas europaea is a widely studied chemolithoautotrophic ammonia oxidizing bacterium. While significant work exists on the ammonia oxidation pathway of N. europaea, its responses to factors such as dissolv...
