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Article
Open AccessAssaying the potential autotoxins and microbial community associated with Rehmannia glutinosa replant problems based on its ‘autotoxic circle’
This study attempted to elucidate the underlying correlations among replant problems of Rehmannia glutinosa, the autotoxins and microbes within its root-zone soil.
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Article
Identification and expression analysis of Rehmannia glutinosa mediator complex genes in response to continuous crop**
The mediator complex, a conserved assembly of multi-functional proteins, is required for the transcription of almost all protein-encoding genes in eukaryotes. In this report, 36 mediator complex subunit transc...
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Article
Knockdown of NtMed8, a Med8-like gene, causes abnormal development of vegetative and floral organs in tobacco (Nicotiana tabacum L.)
Med8, a subunit of mediator complex, has proved to possess crucial functions in many organisms from yeast to human. In plant, the med8 mutant of Arabidopsis thaliana displayed delayed anthesis and increased numbe...
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Article
A New Steroid-Transforming Strain of Mycobacterium neoaurum and Cloning of 3-Ketosteroid 9α-Hydroxylase in NwIB-01
Using enrichment procedures, five strains that can utilize soybean phytosterols as the sole carbon source were isolated from steroids-contaminated soil samples. Among the isolated strains, the strain NwIB-01 w...
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Article
Open AccessSafety and pharmacokinetics of novel selective vascular endothelial growth factor receptor-2 inhibitor YN968D1 in patients with advanced malignancies
YN968D1 (Apatinib) selectively inhibits phosphorylation of VEGFR-2 and tumor angiogenesis in mice model. The study was conducted to determine the maximum tolerated dose (MTD), safety profile, pharmacokinetic v...
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Article
Impact of oxygen supply on rtPA expression in Escherichia coli BL21 (DE3): ammonia effects
In shake flasks, good oxygen supply tended to decrease rtPA expression in media containing only yeast extract and tryptone, while oxygen limitation would increase rtPA synthesis in the same medium. Our data sh...
