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Chapter and Conference Paper
Research and Application of Key Technologies of Nuclear Power Civil Engineering Design Platform
The civil engineering design of nuclear power plants has a long cycle, involves many disciplines, and the design process is complex. The traditional design methods and technical means are backward, mainly two-...
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Article
Loss of bisecting GlcNAcylation on MCAM of bone marrow stoma determined pro-tumoral niche in MDS/AML
Bone marrow (BM) stroma plays key roles in supporting hematopoietic stem cell (HSC) growth. Glycosylation contributes to the interactions between HSC and surrounding microenvironment. We observed that bisectin...
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Article
Open AccessTumour stroma ratio is a potential predictor for 5-year disease-free survival in breast cancer
The tumour–stroma ratio (TSR) is identified as a promising prognostic parameter for breast cancer, but the cutoff TSR value is mostly assessed by visual assessment, which lacks objective measurement. The aims ...
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Article
Design and Achievement of Metallurgical Bonding of Mg/Al Interface Prepared by Liquid–Liquid Compound Casting via a Co-deposited Cu–Ni Alloy Coating
The metallurgical bonding of Mg/Al bimetal by liquid–liquid compound casting was realized via co-deposition Cu–Ni alloy coating. The metallurgical layer of the Mg/Al bimetal consisted of Cu solid solution, Cu2Mg ...
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Article
Open AccessDysregulation and prometastatic function of glycosyltransferase C1GALT1 modulated by cHP1BP3/ miR-1-3p axis in bladder cancer
Abnormal glycosylation in a variety of cancer types is involved in tumor progression and chemoresistance. Glycosyltransferase C1GALT1, the key enzyme in conversion of Tn antigen to T antigen, is involved in bo...
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Article
Preparation of Al2O3/AZ91D Mg Interpenetrating Composites Using Lost Foam Casting Combined with Layered Extrusion Forming
A novel method named lost foam casting (LFC) process combined with layered extrusion forming (LEF) technology was proposed to prepare the Al2O3/AZ91D Mg interpenetrating composites, and the microstructural charac...
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Article
Structure and function of glycosphingolipids on small extracellular vesicles
Extracellular vesicles (EVs) are membrane-delineated particles secreted by most types of cells under both normal and pathophysiological conditions. EVs are believed to mediate intercellular communication by se...
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Chapter and Conference Paper
Review of Transmission Line Icing and Anti-icing Technologies
Icing of transmission lines seriously affects the safety of the power system, and reliable anti-icing technologies guarantee the safe and stable operation of the power system. This paper summarizes the mechani...
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Article
Microstructure, Mechanical Properties and Fracture Behavior of Magnesium/Steel Bimetal Using Compound Casting Assisted with Hot-Dip Aluminizing
In this work, microstructure, mechanical properties and fracture behavior of the magnesium/steel bimetal using compound casting assisted with hot-dip aluminizing were investigated, and the interface bonding me...
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Article
Effects of underwater and semi-aquatic environments on gut tissue and microbiota of the mudskipper Boleophthalmus pectinirostris
In both underwater and semi-aquatic environments, the gut microbiota is of particular physiological importance for amphibious animals, given that the gut tract is among those organs in direct communication wit...
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Article
Crushing Resistance Analysis and Cross-Sectional Parameters Optimization of Flexible Pipe Carcass Layer
As the innermost structure of the flexible pipe, the carcass layer plays the role of bearing the external hydrostatic pressure. How to improve the crushing resistance of the carcass layer is the focus of the r...
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Article
Open AccessSex differences in association between cognitive impairment and clinical correlates in Chinese patients with first-episode drug-naïve schizophrenia
Schizophrenia is a complex mental illness with significant sex differences. Cognitive impairment is common in patients with schizophrenia, even in remission. This study was designed to examine the sex differen...
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Article
Effects of glass fiber size and content on microstructures and properties of KNO3-based water-soluble salt core for high pressure die casting
The water-soluble salt core with higher bending strength and toughness is necessary to withstand the high pressure needed to manufacture some complex parts by high pressure die casting (HPDC). In this paper, t...
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Chapter and Conference Paper
Simulation and Optimization of Multi-UAV Route Planning Based on Hybrid Particle Swarm Optimization
problem (mTSP) is an obviously NP-Hard problems in the optimization of complex planning. By adding much more conditions and meanings to the objective function of the mTSP, the vehicle routing problem ...
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Chapter and Conference Paper
Simulation Research of Arctic Route and Traditional Route Based on the Logit Model
, climate continues to warm. The Arctic ship** routes have become a reality. The opening of the Arctic route will greatly reduce the sea distance between Asia-Europe and Asia-America. It will effecti...
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Chapter
When Glycosylation Meets Blood Cells: A Glance of the Aberrant Glycosylation in Hematological Malignancies
Among neoplasia-associated epigenetic alterations, changes in cellular glycosylation have recently received attention as a key component of hematological malignancy progression. Alterations in glycosylation ap...
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Article
Open AccessCryo-EM structures of human calcium homeostasis modulator 5
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Article
Open AccessSialidase NEU1 suppresses progression of human bladder cancer cells by inhibiting fibronectin-integrin α5β1 interaction and Akt signaling pathway
Sialic acids are widely distributed in animal tissues, and aberrantly expressed in a variety of cancer types. High expression of sialic acid contributes to tumor aggressiveness by promoting cell proliferation,...
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Article
Evaluation and prediction of diffuse axonal injury based on optimization strategy in vehicle collision accidents
The brain is one of the most critical parts of the human body, and it is vulnerable in vehicle collision accidents. Statistically, traumatic brain injuries (TBIs) account for about half of the 1.3 million deat...
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Article
An inverse reconstruction approach considering uncertainty and correlation for vehicle-vehicle collision accidents
Due to the limitation of measurements and the complexity of vehicle collision, uncertain factors inevitably exist in traffic accidents, and they usually are not independent. This makes traffic accident reconst...